KEGG   Ursus arctos horribilis (North American brown bear): 113270586
Entry
113270586         CDS       T05909                                 
Symbol
ADCY3
Name
(RefSeq) adenylate cyclase type 3
  KO
K08043  adenylate cyclase 3 [EC:4.6.1.1]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah00230  Purine metabolism
uah01100  Metabolic pathways
uah01522  Endocrine resistance
uah04015  Rap1 signaling pathway
uah04020  Calcium signaling pathway
uah04022  cGMP-PKG signaling pathway
uah04024  cAMP signaling pathway
uah04062  Chemokine signaling pathway
uah04072  Phospholipase D signaling pathway
uah04114  Oocyte meiosis
uah04211  Longevity regulating pathway
uah04213  Longevity regulating pathway - multiple species
uah04261  Adrenergic signaling in cardiomyocytes
uah04270  Vascular smooth muscle contraction
uah04371  Apelin signaling pathway
uah04540  Gap junction
uah04611  Platelet activation
uah04713  Circadian entrainment
uah04714  Thermogenesis
uah04723  Retrograde endocannabinoid signaling
uah04724  Glutamatergic synapse
uah04725  Cholinergic synapse
uah04727  GABAergic synapse
uah04740  Olfactory transduction
uah04750  Inflammatory mediator regulation of TRP channels
uah04911  Insulin secretion
uah04912  GnRH signaling pathway
uah04913  Ovarian steroidogenesis
uah04914  Progesterone-mediated oocyte maturation
uah04915  Estrogen signaling pathway
uah04916  Melanogenesis
uah04918  Thyroid hormone synthesis
uah04921  Oxytocin signaling pathway
uah04923  Regulation of lipolysis in adipocytes
uah04925  Aldosterone synthesis and secretion
uah04926  Relaxin signaling pathway
uah04927  Cortisol synthesis and secretion
uah04928  Parathyroid hormone synthesis, secretion and action
uah04934  Cushing syndrome
uah04935  Growth hormone synthesis, secretion and action
uah04962  Vasopressin-regulated water reabsorption
uah04970  Salivary secretion
uah04971  Gastric acid secretion
uah04972  Pancreatic secretion
uah04976  Bile secretion
uah05032  Morphine addiction
uah05163  Human cytomegalovirus infection
uah05166  Human T-cell leukemia virus 1 infection
uah05200  Pathways in cancer
uah05207  Chemical carcinogenesis - receptor activation
uah05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    113270586 (ADCY3)
 09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    113270586 (ADCY3)
   04371 Apelin signaling pathway
    113270586 (ADCY3)
   04020 Calcium signaling pathway
    113270586 (ADCY3)
   04072 Phospholipase D signaling pathway
    113270586 (ADCY3)
   04024 cAMP signaling pathway
    113270586 (ADCY3)
   04022 cGMP-PKG signaling pathway
    113270586 (ADCY3)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    113270586 (ADCY3)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    113270586 (ADCY3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    113270586 (ADCY3)
   04062 Chemokine signaling pathway
    113270586 (ADCY3)
  09152 Endocrine system
   04911 Insulin secretion
    113270586 (ADCY3)
   04923 Regulation of lipolysis in adipocytes
    113270586 (ADCY3)
   04912 GnRH signaling pathway
    113270586 (ADCY3)
   04913 Ovarian steroidogenesis
    113270586 (ADCY3)
   04915 Estrogen signaling pathway
    113270586 (ADCY3)
   04914 Progesterone-mediated oocyte maturation
    113270586 (ADCY3)
   04921 Oxytocin signaling pathway
    113270586 (ADCY3)
   04926 Relaxin signaling pathway
    113270586 (ADCY3)
   04935 Growth hormone synthesis, secretion and action
    113270586 (ADCY3)
   04918 Thyroid hormone synthesis
    113270586 (ADCY3)
   04928 Parathyroid hormone synthesis, secretion and action
    113270586 (ADCY3)
   04916 Melanogenesis
    113270586 (ADCY3)
   04925 Aldosterone synthesis and secretion
    113270586 (ADCY3)
   04927 Cortisol synthesis and secretion
    113270586 (ADCY3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    113270586 (ADCY3)
   04270 Vascular smooth muscle contraction
    113270586 (ADCY3)
  09154 Digestive system
   04970 Salivary secretion
    113270586 (ADCY3)
   04971 Gastric acid secretion
    113270586 (ADCY3)
   04972 Pancreatic secretion
    113270586 (ADCY3)
   04976 Bile secretion
    113270586 (ADCY3)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    113270586 (ADCY3)
  09156 Nervous system
   04724 Glutamatergic synapse
    113270586 (ADCY3)
   04727 GABAergic synapse
    113270586 (ADCY3)
   04725 Cholinergic synapse
    113270586 (ADCY3)
   04723 Retrograde endocannabinoid signaling
    113270586 (ADCY3)
  09157 Sensory system
   04740 Olfactory transduction
    113270586 (ADCY3)
   04750 Inflammatory mediator regulation of TRP channels
    113270586 (ADCY3)
  09149 Aging
   04211 Longevity regulating pathway
    113270586 (ADCY3)
   04213 Longevity regulating pathway - multiple species
    113270586 (ADCY3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    113270586 (ADCY3)
   04714 Thermogenesis
    113270586 (ADCY3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    113270586 (ADCY3)
   05207 Chemical carcinogenesis - receptor activation
    113270586 (ADCY3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    113270586 (ADCY3)
   05163 Human cytomegalovirus infection
    113270586 (ADCY3)
  09165 Substance dependence
   05032 Morphine addiction
    113270586 (ADCY3)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    113270586 (ADCY3)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    113270586 (ADCY3)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    113270586 (ADCY3)
Enzymes [BR:uah01000]
 4. Lyases
  4.6  Phosphorus-oxygen lyases
   4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)
    4.6.1.1  adenylate cyclase
     113270586 (ADCY3)
SSDB
Motif
Pfam: Guanylate_cyc AC_N HNOBA NCE101 Peptidase_S49_N
Other DBs
NCBI-GeneID: 113270586
NCBI-ProteinID: XP_026375784
Position
Unknown
AA seq 1145 aa
MPRNQGFSEPEYSAEYSAEYSVSLPSDPDRGVGRTHEISVRNSGSCLCLPRFMRLTFVPE
SLENLYQTYFKRQRHETLLVLVVFAALFDCYVVVMCTVVFSSDKLAPLLVAGMGLLLDIL
LFVLCKKGLLPDRVTRKVVPYLLWLLITAQIFSYLGLNFARAHSASDTVGWQAFFVFSFF
ITLPLSLSPIVIISVVSCVVHTLVLGVTVAQQQQDGLKGMHLLREILANVSLYLCAVAVG
VMSYYMADRKHRKAFLEARQSLEVKMNLEEQSQQQENLMLSILPKHVADEMLKDMKKDES
QKDQQQFNTMYMYRHENVSILFADIVGFTQLSSACSAQELVKLLNELFARFDKLAAKYHQ
LRIKILGDCYYCICGLPDYREDHAVCSILMGLAMVEAISYVREKTKTGVDMRVGVHTGTV
LGGVLGQKRWQYDVWSTDVTVANKMEAGGIPGRVHISQSTLDCLKGEFDVEPGDGGSRCE
YLDEKGIETYLIIASKPEVKKTAAQHGLGGPALLNGAPASSKPSSPALIETKEPNGSIHT
GGSTSEEPEEQETQADNPSFPNPRRRLRLQDLADRVVDASEDEHELNQLLNEALLERESA
QVVKKRNTFLLSMRFMDPDMETRYSVEKEKQSGAAFSCSCVVLLCTALVEILIDPWLMTN
YMTFVVGEVLLLILTICSLAAIFPRAFPKKLVAFSTWIDRTRWARNTWAMLAIFILVMAN
VVDMLSCLQYYTGPTNSTAGLEVEDGCVENPKYYNYVAVLSLIATIMLVQVSHMVKLTLM
LLVTGAVAVINIYAWRPIFDEYDRKRFQEHDFPAVALEKMQGFSTPGLNGTGRLPLVPSK
YSMTAMILVMMLSFYYFSRHVEKLARTLFLWKIEVHDQKERVYEMRRWNEALVTNMLPEH
VARHFLGSKKRDEELYSQSYDEIGVMFASLPNFADFYTEESINNGGIECLRFLNEIISDF
DSLLDNPKFRVITKIKTIGSTYMAASGVTPDVNTNGFASSNKEEKSDKERWQHLADLADF
ALAMKDTLTNINNQSFNNFMLRIGMNKGGVLAGVIGARKPHYDIWGNTVNVASRMESTGV
MGNIQVVEETQAILREYGFRFVRRGTIFVKGKGELLTFFLKGRDKPAAFPNGSSVTLPHQ
VVDNS
NT seq 3438 nt   +upstreamnt  +downstreamnt
atgccgaggaaccagggcttctccgagcctgagtactcggccgagtactccgccgagtac
tcggtcagcctgccctctgaccctgaccgcggggtgggccggacccatgaaatctcggtc
cggaactcgggatcctgcctctgcctgcctcggttcatgcggctgaccttcgtgcccgag
tccttggagaacctgtaccagacctacttcaaacggcagcgccatgagaccctgctggtg
ctggtggtgttcgctgcgctcttcgactgctatgtggtggtcatgtgcacggtggtcttc
tccagcgacaagctggctcccctcctcgtagctgggatgggactgctgttggacatcctc
ctcttcgtactctgcaaaaaggggctgctcccggaccgggtcacccggaaagtggtgccc
tacctgctgtggctactgataactgcccagattttctcttacctgggcctgaactttgcc
cgagcccactcggccagtgacacggtgggctggcaggccttctttgtcttctccttcttc
atcacgctgccgctcagcctcagccccatcgtcatcatctctgtggtctcctgcgttgtg
cacacactcgtcttgggggtcaccgtggcccagcagcagcaggacgggctgaagggcatg
cacttgctgagggagatcctggcgaacgtctccctctacctgtgcgccgtcgccgtgggc
gtcatgtcctactacatggcggaccgcaagcaccgcaaggccttcctggaggcccgccag
tcgctggaggtgaagatgaacctggaggagcagagccagcagcaggagaaccttatgctc
tccatcctgcccaagcacgtggctgacgagatgctgaaggacatgaagaaggacgagagc
cagaaggaccagcagcagttcaacaccatgtacatgtaccggcatgagaacgtcagcatc
ctctttgcggacatcgtgggcttcacccagctgtcttctgcctgcagtgcccaggagctc
gtgaagctgctcaacgagctctttgcccgcttcgacaagctggcagccaaataccaccag
ctgcggattaagatcctaggcgactgttactactgcatctgcggcctgcccgactaccgg
gaggaccacgccgtctgctccatcctcatggggctcgccatggtggaggccatctcgtac
gtgcgggagaagacgaagactggggtggacatgcgcgtgggggtgcacacgggcaccgtg
ctggggggcgtcctgggccagaaacgctggcagtacgacgtgtggtctaccgacgtcact
gtggccaacaagatggaggccggaggcatccccgggcgtgtgcacatctcccagagcacc
ctggactgcctgaagggcgagttcgatgtggagccgggcgacgggggcagccgctgtgag
tacctggacgagaagggcatcgagacctacctcatcatcgcgtccaagccagaggtgaag
aagacagccgcccagcacggcctcggtggcccggccctgctgaacggagccccggcttcc
tccaagcccagctcgcccgccctcatcgagaccaaggagcccaacgggagcatccacacc
ggcggctccacgtcggaggagcccgaggagcaggagacccaggccgacaacccctcgttc
cccaacccacgccggaggctgcgccttcaggacctggctgaccgagtggtggacgcctcc
gaggatgagcacgagctcaaccagctactcaacgaggccctgctggagcgagagtccgcc
caggtggtgaagaagagaaacaccttcctcctttccatgcggttcatggaccccgacatg
gaaacccgctactcagtggagaaggaaaagcagagcggggctgccttcagctgctcctgc
gtcgtcctgctctgtacggccctggtcgagatactcatcgacccctggctaatgacaaac
tacatgacctttgtggttggggaggttctgcttctgatcctgacaatctgctcgctggcc
gccatctttccccgggcctttcctaagaagctcgtggccttctccacttggatcgaccgg
acccgctgggccaggaacacctgggccatgttagccatcttcattctggttatggcaaat
gtcgtggacatgctcagctgtctccagtactacacaggcccaaccaacagcactgcaggg
ctggaggtggaagacggctgcgtcgagaaccccaagtattacaactatgtcgccgtgctg
tccctcatcgccaccatcatgctggtgcaggtcagccacatggtgaagctcacactcatg
ctgctcgtcaccggggctgtggccgtcatcaacatctatgcctggcgccccatctttgat
gaatacgaccgcaaacgttttcaggaacatgacttccctgcagtcgccttagagaagatg
cagggattttccacccctgggctcaatggcaccggcaggctgcccctggtaccttctaag
tactccatgaccgcgatgatcctcgtcatgatgctgagcttctactacttctcacgccac
gtggaaaaattggcaaggacactgttcttgtggaagattgaggtccatgaccagaaggaa
cgggtctacgagatgcggcgctggaacgaggccttggtcaccaacatgttgcctgagcac
gtggcacgccatttcctggggtccaagaagagagatgaggagctgtacagccagtcttac
gatgagatcggagtcatgtttgcctccctgcccaacttcgccgacttctacacggaggag
agcatcaacaacggcggcattgagtgtctgcgcttcctcaacgagatcatctccgacttt
gattctctcctggacaatcccaagttccgggtcatcaccaagatcaaaaccattggcagc
acctacatggccgcttccggagtcaccccggatgtcaacaccaacggctttgccagctcc
aacaaggaggagaagtcagacaaggagcgctggcagcacctggctgatctggccgacttc
gctctggccatgaaggatacgctcacaaacatcaacaaccagtccttcaacaacttcatg
ctgcgcatcggcatgaacaaaggaggggtcctggctggggtcattggagcccggaaacca
cactatgacatctggggcaacacagtcaatgtggccagcaggatggagtccacaggggtc
atgggcaacattcaggtggtggaagaaacacaagccatccttcgagagtacggcttccgc
tttgtgaggcgagggacaatctttgtgaaagggaaaggggagctgctaacctttttcttg
aaggggcgtgataagccagctgccttcccaaatggctcctcggtcaccctgccccaccag
gtggtggacaactcctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (51)   
   KEGG PATHWAY (51)   
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (3)   
   KEGG ENZYME (1)   
   KEGG REACTION (2)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (5)   
   Pfam (5)   
All databases (72)   

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