KEGG   Ursus arctos horribilis (North American brown bear): 113271099
Entry
113271099         CDS       T05909                                 
Symbol
ALOX12
Name
(RefSeq) arachidonate 12-lipoxygenase, 12S-type
  KO
K00458  arachidonate 12-lipoxygenase [EC:1.13.11.31]
Organism
uah  Ursus arctos horribilis (North American brown bear)
Pathway
uah00590  Arachidonic acid metabolism
uah01100  Metabolic pathways
uah01523  Antifolate resistance
uah04726  Serotonergic synapse
uah04750  Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:uah00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    113271099 (ALOX12)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    113271099 (ALOX12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    113271099 (ALOX12)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    113271099 (ALOX12)
Enzymes [BR:uah01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.31  arachidonate 12-lipoxygenase
     113271099 (ALOX12)
SSDB
Motif
Pfam: Lipoxygenase PLAT
Other DBs
NCBI-GeneID: 113271099
NCBI-ProteinID: XP_026376582
Position
Unknown
AA seq 663 aa
MGRYRIRVATGAWLFSGSHNRVQLWLVGARGEAELQLHLRPARGQEEEFERDVPKDLGPL
QFVKLRKHHSLVDDAWFCDLITVRGPGACEEAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQKLYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRVYTLLSSWNRLEDFDQIFWGQKSALAEKVHQCWQDDELFGYQFLNGANPML
LRRSTSLPSRLALPPGMEALGAQLERELQNHSLFEADFILLDGIPANVIRGEKQYLAAPL
VLLKMTPNGKLLPLVIQIQPPSPSSPTPPLFLPSDPPLAWLLAKVWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRRLPGLHPVFKLLIPHIRYTMEINTRARSQLISEGGIFDKAVST
GGGGHVQLLRRAVAQLTYCSLCPPDDLADRGLLGIPGALYAHDALRLWGIIARYVEGIVH
LFYHRDDVVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSQKQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAALNQFQTDLENLEREITARNEQLDLPYDYLKPSRIENS
VTI
NT seq 1992 nt   +upstreamnt  +downstreamnt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcggagctgcagctgcacctgcgg
ccggcgcggggccaggaggaggagtttgagcgcgacgtccccaaggacttggggcccctg
cagttcgtgaagttgcgcaaacaccactccctggtggacgacgcatggttctgcgacctc
atcaccgtgcgcggcccaggagcctgcgaggaggccgccttcccctgctaccgctgggtg
cagggccagggcgtgctgagcctgcccgagggcaccgcacgcctggcaggagacaatgcc
ctggacgtgttccagaagcatcgagagaaagaactgaaagaaagacaaaagctgtactgc
tgggacacctggaaggaggggttacccctgaccatagctgccgggtgtcaggacgatcta
cctccaaacatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggggcactggagatggtcctcaaacgtgtctacaccctcctgagctcctggaaccgcctg
gaggattttgatcagatcttctggggccagaagagtgccctggctgagaaggtccaccag
tgctggcaggacgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctcaacctccctgccctcccggcttgcgctgcccccggggatggaggcactg
ggggcccagctggagagagagctccagaaccattccctgtttgaggctgacttcatcctg
ctggatggaattcccgccaacgtgatccggggcgagaagcagtacctggccgcccccctc
gtcctgctgaagatgacacccaatgggaagctgctgcccctggtcatccagatccagcct
cccagccccagctcccccaccccgccgctgttcctgccctcagatcccccactcgcctgg
ctcctggcaaaggtctgggtccgaaattccgatttccagctgcaccagctccagtatcac
ctgctgaacactcacctggtggccgaggtcatcgctgtggccaccatgaggcgcctcccg
gggctgcaccctgtcttcaagctcctgatcccacacatccgctacaccatggagatcaac
acccgggccagatcccagctcatctcagaaggaggaatatttgacaaggcggtgagcaca
ggaggagggggccatgtacagttgctgcgtcgggccgtggctcagctgacctactgctcc
ctctgtcctcctgacgacctggctgaccggggcctgctgggaatcccaggagccctctat
gcccacgacgctttacggctctgggggatcatcgcccggtacgtggagggcatcgtccac
ctcttctaccacagggatgacgtcgtgagaggggacccggagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccctgtatccttccag
tcccagaagcagctctgccatttccttaccatgtgtgtcttcacatgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggttcctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtaacaatggccacagtgatgggctca
ctacctgatgtccgtcaggcctgtcttcaaatgaccatcacgtggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtacttctcaagccccaaggcc
aaggctgcattaaaccaattccaaacggatttggaaaacctagaaagagagattacagcc
cggaatgagcaactcgacctgccctatgactacctgaagcccagccgcatagagaacagc
gtcactatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (2)   
   Pfam (2)   
All databases (20)   

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