KEGG   Ursus maritimus (polar bear): 103659965
Entry
103659965         CDS       T03271                                 
Symbol
ERBB4
Name
(RefSeq) receptor tyrosine-protein kinase erbB-4
  KO
K05085  receptor tyrosine-protein kinase erbB-4 [EC:2.7.10.1]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04010  MAPK signaling pathway
umr04012  ErbB signaling pathway
umr04020  Calcium signaling pathway
umr04151  PI3K-Akt signaling pathway
umr05014  Amyotrophic lateral sclerosis
umr05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103659965 (ERBB4)
   04012 ErbB signaling pathway
    103659965 (ERBB4)
   04020 Calcium signaling pathway
    103659965 (ERBB4)
   04151 PI3K-Akt signaling pathway
    103659965 (ERBB4)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    103659965 (ERBB4)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    103659965 (ERBB4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103659965 (ERBB4)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     103659965 (ERBB4)
Protein kinases [BR:umr01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   103659965 (ERBB4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Kinase-like Haspin_kinase DUF3951 ABC1
Other DBs
NCBI-GeneID: 103659965
NCBI-ProteinID: XP_008685784
UniProt: A0A384BU71
Position
Unknown
AA seq 1286 aa
MGRYRSRVQTSSCKMMCAGTENKLSSLSDLEQQYRALRKYYENCEVVMGNLEITSIEHNR
DLSFLRSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVFLNYRKDGNFGLQ
ELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVSTNGSSGCGRCHKS
CTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCFACMNF
NDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRACPSSK
MEVEENGIKMCKPCTDICPKACDGIGTGSLMAAQTVDSSNIDKFINCTKINGNLIFLVTG
IHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRVLYSGL
SLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVIRDNRK
AENCTAEGMVCNHLCSNDGCWGPGPDQCLSCRRFSRGRSCIESCNLYDGEFREFENGSIC
VECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKYADQDR
ECHPCHPNCTQGCIGSSIEDCIGLMDRTPLIAAGVIGGLFILVIVGLTFAVYVRRKSIKK
KRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIWVPEGE
TVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQLMPHG
CLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHVKITDF
GLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFGGKPYD
GIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRMARDPQ
RYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTSRARID
SNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVPYRATTSTIPEAPVAQGATAEMF
DDSCCNGTLRKPVAPHVQEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDKPKQEY
LNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANALGNAEYL
KNHVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTNYFYKQNGRIRPIVAENP
EYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq 3861 nt   +upstreamnt  +downstreamnt
atggggagataccgatcaagggtacagacttccagctgtaagatgatgtgtgcaggaaca
gaaaacaagctgagctctctctctgacctggagcagcagtaccgagccttgcgcaaatac
tatgagaactgtgaggtcgtcatgggcaacttggagataaccagcatcgagcacaaccgg
gacctctcctttctgcggtctattcgagaagtcacaggctacgtgttagtggctcttaac
cagtttcgttacctgcctctggagaatttacgcattatccgtgggacaaaactctatgag
gatcgatatgccttggcagtatttctaaactacagaaaagatgggaactttggacttcaa
gaacttgggctgaagaacttgacagaaatccttaatggtggagtgtacgtagaccagaac
aaatttctttgttacacagacacaattcattggcaagatattgttcggaatccatggcct
tccaacttgactctggtgtcaacaaatggtagctcaggatgtggacgttgtcataagtcc
tgtactggccgatgctggggacccacagaaaatcattgccagaccttgacaaggacggtg
tgtgcagagcagtgtgatggcaggtgctatgggccctatgtcagtgactgctgtcataga
gaatgtgctgggggctgctcgggaccgaaggacacagactgctttgcctgcatgaatttc
aatgacagtggagcatgtgttactcagtgtccccaaacttttgtctacaatccaaccacc
tttcaactggagcataacttcaatgcgaagtatacatatggagcattttgtgtcaagaaa
tgcccacataactttgtggtggattccagttcttgtgtgcgtgcctgccctagttccaag
atggaagtagaagaaaatgggattaaaatgtgtaaaccttgcacggatatttgcccaaaa
gcttgtgatggtattggcacaggatcactgatggcagctcagaccgtggattccagtaac
attgacaaattcataaactgcacgaaaatcaatgggaatttgatcttccttgtcactggt
attcatggggacccttacaatgcaattgaagccatagacccagagaaactgaatgttttc
cggacagttcgagagataacaggtttcttgaacatacagtcatggcccccaaacatgact
gacttcagtgttttctctaacctagtgaccatcggtggaagagtcctctatagtggcctc
tccttgcttatccttaagcaacagggcatcacttctctacaattccagtctctgaaggaa
atcagtgcaggaaacatctatattactgacaacagcaacctatgttattatcataccatt
aattggacaacactcttcagcactatcaaccaaagaatagtgatccgggacaataggaaa
gctgaaaactgtactgctgaaggaatggtgtgcaaccatctgtgttcaaacgatggctgt
tggggacctggccccgaccagtgcctgtcctgccgtcgtttcagcagaggaaggagctgc
atcgagtcttgtaacctctatgatggtgaatttcgagagtttgagaatggctccatctgt
gtggagtgtgacccccagtgtgagaagatggaagatggcatcctcacctgccatggaccg
ggacctgacaactgcacaaagtgctcccattttaaagatggtccgaactgtgtggaaaaa
tgtccagatggcctacagggggcaaacagtttcattttcaagtatgctgatcaggatcgg
gagtgccacccatgccatccaaactgcacccaagggtgcataggctcaagtattgaagac
tgcatcggcctgatggatagaactccgctaattgcagcgggagttattggcgggctcttc
atcctggtcatcgtgggtctaacatttgcagtttatgttagaaggaagagcatcaaaaag
aaaagagccttaagaagatttctggaaacagagttagtagaacccttaactcccagtggt
acggcacccaatcaagctcaacttcgtattttaaaagaaacggagctcaaaagagtgaaa
gtactcggctcaggtgcttttggaacagtttataagggtatttgggtacctgaaggagaa
acagtaaagattcctgtggctattaagattcttaatgaaacaactggtcccaaagccaat
gtagagttcatggatgaagctttgatcatggcaagtatggatcatccacacttagtccgg
ttattgggtgtgtgtctgagcccaaccattcagctggttacacagcttatgccccatggc
tgcctgttggattatgtccacgaacacaaggacaacattggatcccagctgctgcttaac
tggtgtgtccagatagctaagggaatgatgtacttggaagaaagacggcttgttcatcgg
gatttggcagcccgaaatgtcttagtgaaatctccaaaccatgtgaaaatcacagatttt
ggactagccagactcttagaaggagatgaaaaagagtataatgctgatggaggaaagatg
ccaattaaatggatggctctggagtgtatacactacaggaaattcacccatcagagtgat
gtttggagctatggagtcactatatgggaactgatgacctttggaggaaaaccctacgat
ggaattccaacccgagaaatcccggatttattagagaaaggcgaacgtttgccccagcct
ccaatctgcactattgacgtttacatggtcatggtcaaatgttggatgattgatgctgac
agtaggcctaaatttaaggaactggctgctgaattttcgaggatggcacgagaccctcaa
agatatctcgttattcagggtgatgatcgcatgaagcttcccagtccaaacgacagcaag
ttctttcagaatctcttggatgaagaggatttggaagacatgatggatgctgaggaatac
ctcgtccctcaggctttcaacatcccacctcccatctatacttccagagcgagaattgac
tcaaataggagtgaaattggacacagccctcctcctgcctacacccccatgtcaggaaac
cagtttgtataccgagatggaggttttgctgcagagcaaggagtacctgtgccctacaga
gccacgaccagcacgatcccagaagctccagttgctcagggggctacagccgagatgttt
gatgactcctgttgtaacggcaccctacgcaagccagtggcaccccacgtgcaggaggac
agcagcacccagaggtacagcgcggaccccaccgtctttgcgccggaacggagcccacga
ggagagctggatgaagaaggttacatgacccctatgcgagataaacctaaacaagaatac
ctgaaccctgtggaggagaacccttttgtttctcggagaaaaaacggagaccttcaagct
ttggataatcccgaatatcacaatgcttccaatggtccacccaaggcagaggatgagtac
gtgaacgagccactgtacctcaacacctttgccaacgcgttggggaatgccgagtacctg
aagaaccatgtactgtctgtgccagagaaggccaagaaagcatttgacaaccctgactac
tggaaccacagcctgccacctcggagcacccttcagcacccagactacctgcaggagtac
agcacaaactatttttataaacaaaatggacggatccggcctattgtggcagagaatcct
gaatacctctctgagttctcgctgaagccaggcacggtgctgcctcctccaccctacaga
caccgaaatactgtggtgtaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (6)   
   KEGG PATHWAY (6)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (28)   

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