KEGG   Ursus maritimus (polar bear): 103660455
Entry
103660455         CDS       T03271                                 
Symbol
ALOX12
Name
(RefSeq) polyunsaturated fatty acid lipoxygenase ALOX12 isoform X1
  KO
K00458  arachidonate 12-lipoxygenase [EC:1.13.11.31]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00590  Arachidonic acid metabolism
umr01100  Metabolic pathways
umr01523  Antifolate resistance
umr04726  Serotonergic synapse
umr04750  Inflammatory mediator regulation of TRP channels
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09103 Lipid metabolism
   00590 Arachidonic acid metabolism
    103660455 (ALOX12)
 09150 Organismal Systems
  09156 Nervous system
   04726 Serotonergic synapse
    103660455 (ALOX12)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    103660455 (ALOX12)
 09160 Human Diseases
  09176 Drug resistance: antineoplastic
   01523 Antifolate resistance
    103660455 (ALOX12)
Enzymes [BR:umr01000]
 1. Oxidoreductases
  1.13  Acting on single donors with incorporation of molecular oxygen (oxygenases)
   1.13.11  With incorporation of two atoms of oxygen
    1.13.11.31  arachidonate 12-lipoxygenase
     103660455 (ALOX12)
SSDB
Motif
Pfam: Lipoxygenase PLAT
Other DBs
NCBI-GeneID: 103660455
NCBI-ProteinID: XP_040485834
UniProt: A0A8M1G0A6
Position
Unknown
AA seq 663 aa
MGRYRIRVATGAWLFSGSHNRVQLWLVGARGEAELQLHLRPARGQEEEFERDVPKDLGPL
QFVKLRKHHSLVDDAWFCDLITVRGPGACEEAAFPCYRWVQGQGVLSLPEGTARLAGDNA
LDVFQKHREKELKERQKLYCWDTWKEGLPLTIAAGCQDDLPPNMRFHEDKRLDFEWALKA
GALEMVLKRVYTLLSSWNRLEDFDQIFWGQKSALAEKVHQCWQDDELFGYQFLNGANPML
LRRSTSLPSRLALPPGMEALGAQLERELQNHSLFEADFILLDGIPANVIRGEKQYLAAPL
VLLKMTPNGKLLPLVIQIQPPSPSSPTPPLFLPSDPPLAWLLAKVWVRNSDFQLHQLQYH
LLNTHLVAEVIAVATMRRLPGLHPVFKLLIPHIRYTMEINTRARSQLISEGGIFDKAVST
GGGGHVQLLRRAVAQLTYCSLCPPDDLADRGLLGIPGALYAHDALRLWGIIARYVEGIVH
LFYHRDDVVRGDPELQAWCREITEVGLCQAQDRGFPVSFQSQKQLCHFLTMCVFTCTAQH
GAINQGQLDWYAWVPNAPCTMRMPPPTTKEDVTMATVMGSLPDVRQACLQMTITWHLGRR
QPDMVPLGHHKEKYFSSPKAKAALNQFQTDLENLEREITARNEQLDLPYDYLKPSRIENS
VTI
NT seq 1992 nt   +upstreamnt  +downstreamnt
atgggccgctaccgcatccgcgtggccaccggggcctggctcttctccgggtcgcacaac
cgcgtgcagctgtggctggtcggggcgcgcggggaggcggagctgcagctgcacctgcgg
ccggcgcggggccaggaggaggagtttgagcgcgacgtccccaaggacttggggcccctg
cagttcgtgaagttgcgcaaacaccactccctggtggacgacgcatggttctgcgacctc
atcaccgtgcgcggcccaggagcctgcgaggaggccgccttcccctgctaccgctgggtg
cagggccagggcgtgctgagcctgcccgagggcaccgcacgcctggcaggagacaatgcc
ctggacgtgttccagaagcatcgagagaaagaactgaaggaaagacaaaagctgtactgc
tgggacacctggaaggaggggttacccctgaccatagctgccgggtgtcaggacgatcta
cctccaaacatgagattccatgaggacaagaggctggacttcgagtgggcactgaaggcg
ggggcactggagatggtcctcaaacgtgtctacaccctcctgagctcctggaaccgcctg
gaggattttgatcagatcttctggggccagaagagtgccctggctgagaaggtccaccag
tgctggcaggacgatgagctttttggctaccagttcctcaatggcgccaaccccatgctg
ttgagacgctcaacctccctgccctcccggcttgcgctgcccccggggatggaggcactg
ggggcccagctggagagagagctccagaaccattccctgtttgaggctgacttcatcctg
ctggatggaattcccgccaacgtgatccggggcgagaagcagtacctggccgcccccctc
gtcctgctgaagatgacacccaatgggaagctgctgcccctggtcatccagatccagcct
cccagccccagctcccccaccccgccgctgttcctgccctcagatcccccactcgcctgg
ctcctggcaaaggtctgggtccgaaattccgatttccagctgcaccagctccagtatcac
ctgctgaacactcacctggtggccgaggtcatcgctgtggccaccatgaggcgcctcccg
gggctgcaccctgtcttcaagctcctgatcccacacatccgctacaccatggagatcaac
acccgggccagatcccagctcatctcagaaggaggaatatttgacaaggcggtgagcaca
ggaggagggggccatgtacagttgctgcgtcgggccgtggctcagctgacctactgctcc
ctctgtcctcctgacgacctggctgaccggggcctgctgggaatcccaggagccctctat
gcccacgacgctttacggctctgggggatcatcgcccggtacgtggagggcatcgtccac
ctcttctaccacagggatgacgtcgtgagaggggacccggagctgcaggcctggtgtcgg
gagatcactgaggtggggctgtgccaggcccaggaccgaggtttccctgtatccttccag
tcccagaagcagctctgccatttccttaccatgtgtgtcttcacatgcactgctcagcat
ggggccatcaaccagggccagctggactggtatgcctgggttcctaatgccccatgcaca
atgcggatgcccccacccaccaccaaggaagatgtaacaatggccacagtgatgggctca
ctacctgatgtccgtcaggcctgtcttcaaatgaccatcacgtggcatctgggtcgccgc
cagccagacatggtgcctctggggcatcacaaagaaaagtacttctcaagccccaaggcc
aaggctgcattaaaccaattccaaacggatttggaaaacctagaaagagagattacagcc
cggaatgaacaactcgacctgccctatgactacctgaagcccagccgcatagagaacagc
gtcactatctga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (5)   
   KEGG PATHWAY (5)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
Protein domain (2)   
   Pfam (2)   
All databases (26)   

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