KEGG   Ursus maritimus (polar bear): 103661071
Entry
103661071         CDS       T03271                                 
Symbol
ACTN4
Name
(RefSeq) alpha-actinin-4
  KO
K05699  actinin alpha 1/4
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04510  Focal adhesion
umr04520  Adherens junction
umr04530  Tight junction
umr04670  Leukocyte transendothelial migration
umr04810  Regulation of actin cytoskeleton
umr05146  Amoebiasis
umr05203  Viral carcinogenesis
umr05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:umr00001]
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    103661071 (ACTN4)
   04520 Adherens junction
    103661071 (ACTN4)
   04530 Tight junction
    103661071 (ACTN4)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103661071 (ACTN4)
 09150 Organismal Systems
  09151 Immune system
   04670 Leukocyte transendothelial migration
    103661071 (ACTN4)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    103661071 (ACTN4)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    103661071 (ACTN4)
  09163 Immune disease
   05322 Systemic lupus erythematosus
    103661071 (ACTN4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103661071 (ACTN4)
  09183 Protein families: signaling and cellular processes
   04812 Cytoskeleton proteins [BR:umr04812]
    103661071 (ACTN4)
   04147 Exosome [BR:umr04147]
    103661071 (ACTN4)
Membrane trafficking [BR:umr04131]
 Exocytosis
  Small GTPases and associated proteins
   Rab associated proteins
    103661071 (ACTN4)
Cytoskeleton proteins [BR:umr04812]
 Eukaryotic cytoskeleton proteins
  Actin filaments / Microfilaments
   Actin-binding proteins
    Cross-linking proteins
     103661071 (ACTN4)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   103661071 (ACTN4)
  Exosomal proteins of colorectal cancer cells
   103661071 (ACTN4)
  Exosomal proteins of bladder cancer cells
   103661071 (ACTN4)
SSDB
Motif
Pfam: Spectrin CH EFhand_Ca_insen EF-hand_1 EF-hand_6 EF-hand_7 EF-hand_8 XisI
Other DBs
NCBI-GeneID: 103661071
NCBI-ProteinID: XP_040489872
UniProt: A0A8M1G5J8
Position
Unknown
AA seq 911 aa
MVDYHAANQSYQYGPSSAGNGAGGGGSMGDYMAQEDDWDRDLLLDPAWEKQQRKTFTAWC
NSHLRKAGTQIENIDEDFRDGLKLMLLLEVISGERLPKPERGKMRVHKINNVNKALDFIA
SKGVKLVSIGAEEIVDGNAKMTLGMIWTIILRFAIQDISVEETSAKEGLLLWCQRKTAPY
KNVNVQNFHISWKDGLAFNALIHRHRPELIEYDKLRKDDPVTNLNNAFEVAEKYLDIPKM
LDAEDIVNTARPDEKAIMTYVSSFYHAFSGAQKAETAANRICKVLAVNQENEHLMEDYER
LASDLLEWIRRTIPWLEDRVPQKTIQEMQQKLEDFRDYRRVHKPPKVQEKCQLEINFNTL
QTKLRLSNRPAFMPSEGRMVSDINNGWQHLEQAEKGYEEWLLNEIRRLERLDHLAEKFRQ
KASIHEAWTDGKEAMLKHRDYETATLSDIKALIRKHEAFESDLAAHQDRVEQIAAIAQEL
NELDYYDSHNVNTRCQKICDQWDALGSLTQSRREALEKTEKQLETIDQLHLEYAKRAAPF
NNWMESAMEDLQDMFIVHTIEEIEGLISAHDQFKSTLPDADREREAILAIHKEAQRIAES
NHIKLSGSNPYTTVTPQIINSKWEKVQQLVPKRDHALLEEQSKQQSNEHLRRQFASQANI
VGPWIQTKMEEIGRISIEMNGTLEDQLNHLKRYERSIVDYKPNLDLLEQQHQLIQEALIF
DNKHTNYTMEHIRVGWEQLLTTIARTINEVENQILTRDAKGISQEQMQEFRASFNHFDKD
HGGALGPEEFKACLISLGYDVENDRQGDAEFNRIMSVVDPNHSGLVTFQAFIDFMSRETT
DTDTADQVIASFKVLAGDKNFITAEELRRELPPDQAEYCIARMAPYQGPDAVPGALDYKS
FSTALYGESDL
NT seq 2736 nt   +upstreamnt  +downstreamnt
atggtggactaccacgcggcgaaccagtcgtaccagtacggccccagcagcgcgggcaat
ggcgccggcggcgggggaagcatgggcgactacatggcccaggaggacgactgggaccgg
gacctgctgctggacccggcctgggagaagcagcagcgcaagacattcacagcctggtgc
aactcccacctgcggaaggctggcacgcagatagagaacatcgacgaggacttccgagac
gggctcaagctcatgctccttctagaggtcatttcaggagagcggttacctaagccagag
cggggcaagatgagagtgcacaagatcaacaatgtgaacaaagctctggacttcatcgcc
agcaaaggagtcaagctcgtctccatcggggcagaagagattgtggacggtaatgcaaag
atgaccctgggaatgatctggaccatcatcctcaggttcgccatccaggacatctccgtg
gaagagacctctgccaaggagggactgcttctgtggtgccagaggaagacggccccgtat
aagaacgtcaacgtgcagaacttccacatcagctggaaggacggtcttgccttcaatgca
ctgatccaccggcacagaccagagctgatcgagtatgacaagctgagaaaggatgacccc
gttaccaacctgaacaatgctttcgaagtggccgagaaatacctagacatccccaagatg
ttggatgctgaggacatcgtgaacacggcccggcccgacgagaaggccataatgacctat
gtgtccagcttctaccatgccttttcgggagcgcagaaggctgagactgcggccaaccgg
atctgcaaggtgctggccgtcaaccaagagaatgagcacctcatggaagattatgagagg
ctggccagtgatctcctggagtggatccggcgtaccatcccctggctggaggaccgggtg
ccgcagaagaccatccaggagatgcagcagaagctggaggacttccgggactaccggcgt
gtgcacaagccgcccaaggtgcaggagaagtgccagctggagatcaacttcaacacgctg
cagaccaaactgcgcctcagcaaccggcccgccttcatgccctccgagggcaggatggtc
tcggacatcaacaacggctggcagcacctggagcaggccgagaagggctacgaggagtgg
ctgctgaatgagatccgcaggctggagcggcttgaccacctggcagagaagttccggcag
aaggcctccatccacgaggcctggaccgacgggaaggaagccatgctgaagcaccgggac
tacgagacagccaccctgtcggatatcaaagccctcattcgcaagcacgaggcctttgag
agcgacctggccgcacaccaggaccgagtggagcagattgcggccattgctcaggagctc
aacgagctggactactacgactcccacaacgtcaacacccgctgccagaagatctgcgac
cagtgggatgccctcggctctctgacccagagtcgcagggaagctctggagaaaacggag
aagcagctggagaccattgaccagctgcacctggagtacgccaagcgggcggcgcccttc
aacaactggatggagagcgccatggaggacctgcaggacatgttcatcgtccacaccatt
gaggagatcgagggcctgatttcagctcacgaccagttcaagtcgacgctgccggacgcc
gacagggagcgggaggccatcctggccatccacaaggaggcgcagaggatcgctgagagc
aaccacatcaagctgtcgggcagcaacccctacaccaccgtcaccccacagatcatcaac
tccaagtgggagaaggtgcagcagctggtgcccaagcgggaccacgccctcctggaggag
cagagcaagcagcagtccaacgagcacctccgccgccagtttgccagccaggccaacatt
gtggggccctggatccagacgaagatggaggagatcgggcgcatctccatcgagatgaac
gggaccctggaggaccagctgaaccacttgaagcggtacgagcgcagcatcgtggactac
aagccgaacctcgacctgctcgagcagcagcaccagctcatccaggaggccctcatcttc
gacaacaagcacaccaactacaccatggagcacatccgcgtgggctgggagcagctgctc
accaccatcgcccgcaccatcaacgaggtcgagaaccagatcctcacccgtgatgccaag
ggcatcagccaggagcagatgcaggagttccgggcgtccttcaaccacttcgacaaggac
cacggcggggcgctggggccggaggagttcaaggcctgtctcatcagcctgggctacgac
gtggagaatgaccggcagggtgatgccgagttcaaccgcatcatgagcgtggttgacccc
aaccacagtgggctcgtgaccttccaagccttcattgacttcatgtcaagggagaccacc
gacacagatacggccgaccaggtcatcgcctccttcaaggtcctggcaggggacaagaac
ttcatcacagctgaggagctgcggagagagctgcccccggaccaggctgagtactgcatc
gcacgcatggcgccctatcagggccccgacgctgtgcccggcgccctcgactacaagtcc
ttctcgacagccctgtacggcgagagtgacctgtga

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (8)   
   KEGG PATHWAY (8)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (5)   
   RefSeq(nuc) (1)   
   GenBank (2)   
   EMBL (2)   
Protein domain (8)   
   Pfam (8)   
All databases (32)   

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