KEGG   Ursus maritimus (polar bear): 103663192
Entry
103663192         CDS       T03271                                 
Symbol
SYK
Name
(RefSeq) tyrosine-protein kinase SYK isoform X1
  KO
K05855  spleen tyrosine kinase [EC:2.7.10.2]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04064  NF-kappa B signaling pathway
umr04072  Phospholipase D signaling pathway
umr04151  PI3K-Akt signaling pathway
umr04380  Osteoclast differentiation
umr04611  Platelet activation
umr04613  Neutrophil extracellular trap formation
umr04625  C-type lectin receptor signaling pathway
umr04650  Natural killer cell mediated cytotoxicity
umr04662  B cell receptor signaling pathway
umr04664  Fc epsilon RI signaling pathway
umr04666  Fc gamma R-mediated phagocytosis
umr05152  Tuberculosis
umr05167  Kaposi sarcoma-associated herpesvirus infection
umr05168  Herpes simplex virus 1 infection
umr05169  Epstein-Barr virus infection
umr05171  Coronavirus disease - COVID-19
umr05203  Viral carcinogenesis
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    103663192 (SYK)
   04072 Phospholipase D signaling pathway
    103663192 (SYK)
   04151 PI3K-Akt signaling pathway
    103663192 (SYK)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103663192 (SYK)
   04613 Neutrophil extracellular trap formation
    103663192 (SYK)
   04625 C-type lectin receptor signaling pathway
    103663192 (SYK)
   04650 Natural killer cell mediated cytotoxicity
    103663192 (SYK)
   04662 B cell receptor signaling pathway
    103663192 (SYK)
   04664 Fc epsilon RI signaling pathway
    103663192 (SYK)
   04666 Fc gamma R-mediated phagocytosis
    103663192 (SYK)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103663192 (SYK)
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    103663192 (SYK)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    103663192 (SYK)
   05168 Herpes simplex virus 1 infection
    103663192 (SYK)
   05167 Kaposi sarcoma-associated herpesvirus infection
    103663192 (SYK)
   05169 Epstein-Barr virus infection
    103663192 (SYK)
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    103663192 (SYK)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:umr01001]
    103663192 (SYK)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     103663192 (SYK)
Protein kinases [BR:umr01001]
 Non-receptor tyrosine kinases
  SYK family
   103663192 (SYK)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase SH2 Kdo ABC1 RIO1
Other DBs
NCBI-GeneID: 103663192
NCBI-ProteinID: XP_040476268
UniProt: A0A8M1EYT3
Position
Unknown
AA seq 635 aa
MAGNTADSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKA
HHYTIEREMNGTYAIAGGRTHSSPAELCLYHSQESDGLVCVLKKPLHRPPGVQPKTGPFE
DLKESLIREYVKQTWNLQGQALEQAIISQKPQLEKLIATTAHEKMPWFHGKISRVESEQI
VMIGSKTNGKFLIRDRNDNGSYALCLLHEGKVLHYRIDKDKTGKLSIPDGKKFDTLWQLV
EHYSYKPDGLLRVLTVPCQKIGGQTGNINFGARAPLPGAHPATWSAGAIISRIKSYSFPK
PGHRKASSSTGNRPESSVTFNPYEPDRGPWATDRDAQREAMPMDTEVYESPYADPEEIRP
KEVYLDRKLLTLEDSELGSGNFGTVKKGYYQMKKVVKTVAVKILKNEANDPALKDELLAE
ANVMQQLDNPYIVRMIGICEAESWMLVMEMAELGPLNKYLQQNRHVKDKNIIELVHQVSM
GMKYLEECNFVHRDLAARNVLLVTQHYAKISDFGLSKALRADESYYKAQTHGKWPVKWYA
PECINYYKFSSKSDVWSFGVLMWEAFSYGQKPYRGMKGSEVSAMLEKGERMGCPAGCPRE
MYELMKLCWTYEVEKRPGFENVELRLRNYYYDVVN
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggcgggaaacacggccgacagcgccaaccacctgccattcttcttcggcaacatcacg
cgggaggaggcggaggactacctggtgcaggggggcatgagcgacgggctgtacctgctg
cgtcagagccgcaattacctgggcggcttcgcgctgtcggtggcgcacgggaggaaggcg
caccactacaccatcgagcgcgagatgaacggcacctacgccatcgcgggcggcaggacg
cacagcagcccggccgagctgtgcctctaccactcccaggagtccgacggcctcgtctgc
gtcctcaagaagcccctccaccggccgcccggggtgcagcccaagaccggcccgttcgag
gacctgaaggagagcctcatcagggagtacgtgaagcagacctggaacctgcagggtcag
gctctggagcaggccatcatcagccagaagcctcagctggagaagctgatcgccaccacg
gcccacgagaaaatgccctggttccacgggaaaatctcacgggttgaatctgagcaaatt
gtcatgataggatccaagacaaacggaaaatttttgatcagggacaggaacgacaacggg
tcttacgccctgtgcctgctgcacgaggggaaggtgctgcactatcgcatcgacaaggac
aaaaccgggaagctctccatccccgacgggaagaagttcgacacgctctggcagctcgtg
gagcattactcttacaaaccggacgggctgttgagagttcttacggttccgtgccagaaa
attggcgggcagacaggaaacatcaactttggagcccgcgcgcccctgccaggtgcccac
cctgcgacgtggtcagcgggcgcgataatctccagaatcaaatcctactccttcccaaag
cccggccacagaaaggcctcctcgtccacagggaaccggcccgagagctccgtgaccttc
aatccttatgagccagaccgggggccctgggccacggacagagacgcgcagagagaagcc
atgcccatggacaccgaggtgtacgaaagcccctacgccgaccccgaggagatcaggccc
aaggaggtctacctggaccgcaagctgctgaccctggaggacagtgagctgggctctggg
aacttcgggaccgtgaagaagggctactaccagatgaaaaaagtcgtgaagacagtggct
gtgaagattctgaagaacgaggccaatgaccctgctcttaaagacgagttattagcagag
gcgaacgtcatgcagcagctcgataacccttacatcgtgcgcatgatcgggatatgtgaa
gccgagtcctggatgctggtcatggagatggcggaactggggccactcaataaatactta
cagcagaacaggcacgtcaaggataagaacatcatagagctggttcatcaggtttctatg
ggaatgaaatatctggaggagtgcaattttgtgcacagagatctggctgcaagaaacgta
ttgctggttactcaacattatgccaagattagtgatttcggactttccaaagcactccgt
gctgacgaaagctactataaggcccagacccacgggaagtggccggtgaagtggtacgct
ccggagtgcattaactactacaagttctccagcaagagcgacgtctggagctttggcgtg
ctgatgtgggaggcgttctcctacggccagaagccctaccggggcatgaaaggaagtgaa
gtttcggctatgctggagaaaggggagaggatggggtgccccgcgggatgtccgagggag
atgtacgagctgatgaagctgtgctggacatatgaggtggagaagaggcccggcttcgaa
aacgtggagctgcgtctgcgcaattactactatgacgtggtgaactaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (17)   
   KEGG PATHWAY (17)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
Protein domain (6)   
   Pfam (6)   
All databases (41)   

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