KEGG   Ursus maritimus (polar bear): 103667123
Entry
103667123         CDS       T03271                                 
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1
  KO
K05853  P-type Ca2+ transporter type 2A [EC:7.2.2.10]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04020  Calcium signaling pathway
umr04022  cGMP-PKG signaling pathway
umr04024  cAMP signaling pathway
umr04148  Efferocytosis
umr04260  Cardiac muscle contraction
umr04261  Adrenergic signaling in cardiomyocytes
umr04380  Osteoclast differentiation
umr04919  Thyroid hormone signaling pathway
umr04972  Pancreatic secretion
umr05010  Alzheimer disease
umr05017  Spinocerebellar ataxia
umr05022  Pathways of neurodegeneration - multiple diseases
umr05410  Hypertrophic cardiomyopathy
umr05412  Arrhythmogenic right ventricular cardiomyopathy
umr05414  Dilated cardiomyopathy
umr05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    103667123 (ATP2A3)
   04024 cAMP signaling pathway
    103667123 (ATP2A3)
   04022 cGMP-PKG signaling pathway
    103667123 (ATP2A3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    103667123 (ATP2A3)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    103667123 (ATP2A3)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    103667123 (ATP2A3)
   04261 Adrenergic signaling in cardiomyocytes
    103667123 (ATP2A3)
  09154 Digestive system
   04972 Pancreatic secretion
    103667123 (ATP2A3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    103667123 (ATP2A3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    103667123 (ATP2A3)
   05017 Spinocerebellar ataxia
    103667123 (ATP2A3)
   05022 Pathways of neurodegeneration - multiple diseases
    103667123 (ATP2A3)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    103667123 (ATP2A3)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    103667123 (ATP2A3)
   05414 Dilated cardiomyopathy
    103667123 (ATP2A3)
   05415 Diabetic cardiomyopathy
    103667123 (ATP2A3)
Enzymes [BR:umr01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.10  P-type Ca2+ transporter
     103667123 (ATP2A3)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD TNP-like_RNaseH_N DUF3106
Other DBs
NCBI-GeneID: 103667123
NCBI-ProteinID: XP_040497116
UniProt: A0A8M1GN30
Position
Unknown
AA seq 999 aa
MEAAHLLPAADVLSRFSVTVESGLRPEQVSGARERYGPNELPTEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLACFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRSDRKGVQRVRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTDAIPDPRAVNQDKKNMVFSGTNIASGKALGVAVATGLHTELGKIRSQMA
AVEPERTPLQHKLDEFGRQLSRAISVICVAVWVINISHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEAEAGTCRLHEFTISGTTYAPEGEVRQAEQLVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTNLQTLSPVERASACNAVIKQLMR
KEFTLEFSRDRKSMSVYCTPTSPGLAAQGSKMFVKGAPESVIERCSSVRVGSHTVPLNAT
SREQILAKIRDWGSGSDMLRCLALATRDSPPRKEDMQLDNCSKFVQYEMDLTFVGCVGML
DPPRPEVAACITRCHQAGIRVVMITGDNKGTAVAICRRLGIFRDTEDVVGKAYTGREFDD
LSPEQQRHACRTACCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKMPRNPHEALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPHVTFYQLRNFLKCSEDNPLFADIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWLNPWLLAAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVLVLQISLPVILLDEALKYLSRNHMDEEKDQK
NT seq 3000 nt   +upstreamnt  +downstreamnt
atggaggcggcgcacctgctcccggctgcagacgtgctgagccgcttctcggtgacggtc
gagagcggactgaggccggagcaggtgtctggcgcgcgggagcgctacggccccaacgag
ctcccaactgaggaagggaagtccctgtgggagctggtgctggagcagtttgaggacctc
ctggtgcgcatcctgctgttggctgccctggtctccttcgtcctggcctgctttgaggag
ggcgaagagaccacgacagccttcgtggagcccctggtcatcatgttgatccttgtggcc
aatgctatcgtgggcgtatggcaggaacgcaatgctgagagtgccattgaggccttgaag
gagtatgagcctgagatgggcaaggtgatccgctcagaccgcaaaggtgtgcagagggtc
cgcgcccgggacatcgtccctggagacatcgtggaggtggcagtgggagacaaagtaccc
gctgacctccgcctcatcgagatcaagtccaccacactgagagtagaccagtccatcctg
acaggtgaatccgtgtctgtgaccaagcacacagatgccatcccagatcccagagctgtg
aaccaggacaagaagaacatggttttctctggcaccaatatcgcatcaggcaaggccctg
ggtgtggcagtggccacaggcctgcacacagagctgggtaagatccggagtcagatggcg
gcagtggagccggagcggacgccgctgcagcacaagctggatgagtttgggcggcagctg
tcccgtgccatctctgtgatctgtgtggctgtgtgggtcatcaacatcagccactttgct
gacccggcccatggtggctcctggctccgtggtgctgtctactacttcaagattgccgtg
gccctggcggtggctgccatccctgagggcctcccagccgttatcactacatgcctggct
ctgggcacacggcgcatggcacgcaagaatgccattgtgcgaagcctgccctctgtggag
accctgggctgcacctcagtcatctgctccgacaagacaggcacactcaccaccaatcag
atgtctgtctgccggatgttcgtggtagccgaggccgaagcaggcacctgccgtttgcac
gagttcaccatctcaggcaccacttatgccccggagggcgaagtgaggcaggcggagcag
cttgtgcgctgtgggcagtttgatgggctggtggagctggcgacaatctgtgccctgtgc
aatgactcagcgctggactacaacgaggctaagggcgtgtatgagaaggtgggagaggcc
acggagactgctctgacttgcctggtggagaaaatgaatgtgtttgacaccaacctacag
accctctccccggtggagcgagccagtgcctgcaatgcggtcatcaagcagctgatgcgg
aaggagtttactttggagttctcccgagaccggaagtccatgtcagtgtactgcacaccg
actagccctggcctggcagcccagggcagcaagatgtttgtgaagggggctcctgagagt
gtgatcgagcgctgtagctcagtccgagtgggaagccatacagtacccctgaatgccacc
tccagggagcagatcttggccaagattcgggattggggctcaggctcagacatgttgcgc
tgcctggcactggccactcgggattcacccccaaggaaggaggacatgcagctggacaac
tgcagcaagtttgtgcaatacgagatggacctcacttttgtgggctgcgtgggcatgctg
gaccctccaaggcccgaggtggctgcttgtatcacacgctgccaccaggccggcatccgt
gtggtcatgatcacaggggacaacaaaggcacagctgtggccatctgccgccggcttggc
atcttcagggacacagaggacgtggtggggaaggcctacacaggtcgcgaattcgatgac
ctcagccctgagcagcagcgccatgcctgccgcacagcatgctgttttgcccgtgtggaa
cctgcacacaagtcccgaatcgtagagaacctacagtccttcaacgagatcactgccatg
actggagacggggtgaatgatgccccagctttgaagaaagcagagattggcattgccatg
ggctctggcacagctgtagccaagtcagcagccgagatggtgctgtcagatgacaacttt
gcctccatcgtggctgcagtggaggagggccgggccatctacaacaacatgaagcaattc
atccgctacctcatctcctccaatgtaggcgaggttgtctgcatcttcctcacggcaatt
ctgggcctcccggaagccctgatccctgtgcagctgctctgggtgaacctggtgacagat
ggtctacctgccacagccctgggcttcaaccccccagacctggacatcatggagaagatg
ccgaggaaccctcatgaggccctcatcagtggctggctcttttttcgatatctggctatt
ggagtgtacgtaggcctggccacggtggctgccgccacctggtggttcctttatgatgcc
gagggacctcacgtcaccttctaccaactgaggaacttcctgaagtgctccgaggacaac
ccactctttgccgacattgactgcgaggtcttcgagtcacgctttcccacaaccatggcc
ttgtctgtgctggtgaccattgaaatgtgcaatgccctcaacagtgtctcagagaaccag
tcgctgctgcggatgccaccctggctgaacccttggctgctggcagctgtggccatgtcc
atggccctgcacttcctcatccttctggtgccacccctgcctcttattttccaggtgacc
ccactgagcgggcgccagtgggtgctggtgctccagatatctctgcctgtcatccttctt
gatgaagccctcaagtacctgtcccggaaccacatggatgaagaaaaggaccagaagtga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (16)   
   KEGG PATHWAY (16)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (5)   
   UniProt (1)   
   RefSeq(pep) (4)   
DNA sequence (8)   
   RefSeq(nuc) (4)   
   GenBank (2)   
   EMBL (2)   
Protein domain (9)   
   Pfam (9)   
All databases (46)   

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