KEGG   Ursus maritimus (polar bear): 103672113Help
Entry
103672113         CDS       T03271                                 

Gene name
ATP1A2
Definition
(RefSeq) ATPase Na+/K+ transporting subunit alpha 2
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04022  cGMP-PKG signaling pathway
umr04024  cAMP signaling pathway
umr04260  Cardiac muscle contraction
umr04261  Adrenergic signaling in cardiomyocytes
umr04911  Insulin secretion
umr04918  Thyroid hormone synthesis
umr04919  Thyroid hormone signaling pathway
umr04925  Aldosterone synthesis and secretion
umr04960  Aldosterone-regulated sodium reabsorption
umr04961  Endocrine and other factor-regulated calcium reabsorption
umr04964  Proximal tubule bicarbonate reclamation
umr04970  Salivary secretion
umr04971  Gastric acid secretion
umr04972  Pancreatic secretion
umr04973  Carbohydrate digestion and absorption
umr04974  Protein digestion and absorption
umr04976  Bile secretion
umr04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    103672113 (ATP1A2)
   04022 cGMP-PKG signaling pathway
    103672113 (ATP1A2)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    103672113 (ATP1A2)
   04918 Thyroid hormone synthesis
    103672113 (ATP1A2)
   04919 Thyroid hormone signaling pathway
    103672113 (ATP1A2)
   04925 Aldosterone synthesis and secretion
    103672113 (ATP1A2)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    103672113 (ATP1A2)
   04261 Adrenergic signaling in cardiomyocytes
    103672113 (ATP1A2)
  09154 Digestive system
   04970 Salivary secretion
    103672113 (ATP1A2)
   04971 Gastric acid secretion
    103672113 (ATP1A2)
   04972 Pancreatic secretion
    103672113 (ATP1A2)
   04976 Bile secretion
    103672113 (ATP1A2)
   04973 Carbohydrate digestion and absorption
    103672113 (ATP1A2)
   04974 Protein digestion and absorption
    103672113 (ATP1A2)
   04978 Mineral absorption
    103672113 (ATP1A2)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    103672113 (ATP1A2)
   04961 Endocrine and other factor-regulated calcium reabsorption
    103672113 (ATP1A2)
   04964 Proximal tubule bicarbonate reclamation
    103672113 (ATP1A2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103672113 (ATP1A2)
Enzymes [BR:umr01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     103672113 (ATP1A2)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   103672113 (ATP1A2)
  Exosomal proteins of other body fluids (saliva and urine)
   103672113 (ATP1A2)
  Exosomal proteins of colorectal cancer cells
   103672113 (ATP1A2)
  Exosomal proteins of bladder cancer cells
   103672113 (ATP1A2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Hydrolase Cation_ATPase_N Hydrolase_3 Sigma70_r4
Motif
Other DBs
NCBI-GeneID: 103672113
NCBI-ProteinID: XP_008699006
UniProt: A0A384CW35
Position
Un
AA seq 1062 aa AA seqDB search
MGVLFEVGEARGHGSQVTKRFRHWLSGRPFFLSSRAATTAENGGGKKKQKEKELDELKKE
VAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDILARDGPNALTPPPTTPEWVKFCRQLFG
GFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIVTGCFSYYQEAKSSKIM
DSFKNMVPQQALVVREGEKMQINAEEVVVGDLVEVKGGDRVPADLRIISSHGCKVDNSSL
TGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATGDRTVMGRIATLASGLE
VGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVIFLIGIIVANVPEGLLA
TVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIH
EADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISVSKRDTAGDASESALLK
CIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHEREDSPQSHVLVMKGAPERILDRCS
TILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFPQLNLPSGKFPRGFRFDTDELNFP
TEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNE
TVEDIAARLNIPVSQVNPREAKACVVHGSDLKDMTSEQLDEILKNHTEIVFARTSPQQKL
IIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAADMILLDDNFASIV
TGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPLGTVTILCIDLGTDMVPA
ISLAYEAAESDIMKRQPRNPQTDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFL
PSRLLGIRLDWDDRSMNDLEDSYGQEWTYEQRKVVEFTCHTAFFASIVVVQWADLIICKT
RRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYPLKVTWWFCDQNSSSWQF
CPFFKPGREGVGKFLQRDTQMGQVRAPPKEPRRPKAERKEAR
NT seq 3189 nt NT seq  +upstreamnt  +downstreamnt
atgggggtcctgtttgaggttggagaggccagggggcatggctcccaagtcaccaagcgg
ttccgacactggctctcaggccggccgttttttttgtcctcacgtgcagccaccactgcg
gagaatgggggcggcaagaagaagcagaaagagaaggagctggatgagctgaagaaggag
gtggccatggatgaccacaagctgtccttggatgagctgggccgcaagtaccaagtggac
ctctccaagggcctcaccaaccagcgggcccaggacattctggctcgggatggacccaat
gccctcaccccgcccccgacaacccccgagtgggtcaagttctgtcgccagctcttcggg
ggcttctccatcctgctgtggatcggggccatcctctgcttcctggcctatggcatccag
gctgccatggaggatgaaccatccaacgacaacctctatctgggcgtggtgctggcagcg
gtggtcatcgtcaccggctgcttctcctactatcaggaggccaagagctccaagatcatg
gattccttcaagaacatggtgcctcagcaagcccttgtggtgcgggaaggagagaagatg
cagatcaacgcggaggaggttgtggtgggagacctggtggaggtgaagggtggggaccgc
gtgcctgcggacctccgcatcatctcttctcacggctgcaaggtggataactcatccctc
acgggcgagtcggagccccagacccgctcccccgagttcacccacgagaaccccctggag
acccgcaacatctgcttcttctccaccaactgtgtggaaggcacggccaggggcatcgtg
atcgccacaggtgaccggacggtgatgggccgcatagccaccctggcctcgggcctggag
gtggggcggacacccatcgccatggagatcgagcacttcatccagctgatcacaggggtg
gccgtgttcctgggggtctctttcttcgtgctctccctcatcctgggctacagctggctg
gaggccgtcatcttcctcatcggcatcatcgtggccaatgtgcctgaggggctgctggcc
actgtcaccgtgtgtctgaccctgacggccaagcgcatggcccggaagaactgcctggtg
aagaatctggaggcagtggagacgctgggctccacctccaccatctgctccgacaagacg
ggcaccctcacccagaaccgcatgaccgtcgcccacatgtggtttgacaaccagatccac
gaagccgacaccactgaggatcagtctggggccacttttgacaaacgatcccccacgtgg
acggccctgtctcggatcgctggtctctgcaaccgcgctgtcttcaaggccgggcaggag
aacatctctgtgtctaagcgggacacagccggcgacgcctcggagtcagctctgctcaag
tgcattgagctgtcctgcggctccgtgaggaagatgagggacagaaaccccaaggtggca
gagatccctttcaattccaccaacaagtaccagctgtccatccacgagcgagaagacagc
ccccagagccacgtgctggtgatgaagggggccccggagcgcatcctggaccggtgctcc
accatcttggtgcagggcaaggagatccctctggacaaggagatgcaagacgccttccag
aacgcctacatggagctgggcgggctgggggagcgcgtgctggggtttcctcaactgaat
ctgccctctgggaagtttccccggggcttcaggtttgacacagacgagctgaactttccc
acggagaagctctgcttcgtggggctcatgtctatgatcgaccctccccgggctgctgtg
ccggacgccgtgggcaagtgccgcagcgccggcatcaaggtaatcatggtgaccggggac
caccccatcacagccaaggccatcgccaaaggtgtgggcattatatcagaaggcaacgag
acggtggaggacattgcggcccggctcaacattcctgtcagccaggtcaaccccagagaa
gccaaggcgtgcgtggtgcacggctcggacctgaaggacatgacatcggagcagctggac
gagatcctgaagaaccacacggagatcgtgttcgcgcggacgtccccacagcagaagctc
atcatcgtggagggctgccagaggcagggggccatcgtggcggtgaccggggatggcgtg
aacgactcccctgcactgaagaaggccgacatcggcatcgccatgggcatctcgggctcc
gacgtgtcgaagcaggcggccgacatgatcctcctggacgacaacttcgcctccatcgtc
acgggcgtggaggagggccgcctcatctttgacaacctgaagaaatccatcgcatacaca
ctgaccagcaacatccccgagatcacccccttcctgcttttcatcattgccaacatcccc
ctgcctctgggtaccgtgaccatcctctgcatcgacctgggcacggacatggtccccgcc
atctccttggcctacgaggccgcggagagtgacatcatgaagcggcagccgaggaaccca
cagacggacaagctggtgaatgagaggctcatcagcatggcctacggacagatcggaatg
atccaggcgctgggcggcttcttcacctacttcgtcatcctggcagagaacggtttcctg
ccatcgcggctgctgggaatccgcctggactgggacgaccggtccatgaacgatctggag
gacagctacgggcaggagtggacctatgagcagcgcaaggtggtggagttcacctgccac
acggccttcttcgccagcatcgtggtcgtgcagtgggctgacctcatcatctgcaagacc
cgacgcaactcggtcttccaacagggcatgaagaacaagattctgattttcgggctgctg
gaggagacggcgctggcggccttcctgtcctactgcccgggcatgggcgtggccctccgc
atgtacccgctcaaggtcacctggtggttctgtgatcagaacagttcctcctggcagttc
tgccccttctttaagcccggccgagaaggcgttgggaagttcctgcagagagacacccag
atgggccaagtgagagcgccacctaaggaacccaggagacctaaggcagaaaggaaggag
gcccgctaa

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