KEGG   Ursus maritimus (polar bear): 103672248Help
Entry
103672248         CDS       T03271                                 

Gene name
HSPA2
Definition
(RefSeq) heat shock protein family A (Hsp70) member 2
  KO
K03283  heat shock 70kDa protein 1/2/6/8
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr03040  Spliceosome
umr04010  MAPK signaling pathway
umr04141  Protein processing in endoplasmic reticulum
umr04144  Endocytosis
umr04213  Longevity regulating pathway - multiple species
umr04612  Antigen processing and presentation
umr04915  Estrogen signaling pathway
umr05134  Legionellosis
umr05145  Toxoplasmosis
umr05162  Measles
Brite
KEGG Orthology (KO) [BR:umr00001]
 09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    103672248 (HSPA2)
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    103672248 (HSPA2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    103672248 (HSPA2)
 09140 Cellular Processes
  09141 Transport and catabolism
   04144 Endocytosis
    103672248 (HSPA2)
 09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    103672248 (HSPA2)
  09152 Endocrine system
   04915 Estrogen signaling pathway
    103672248 (HSPA2)
  09149 Aging
   04213 Longevity regulating pathway - multiple species
    103672248 (HSPA2)
 09160 Human Diseases
  09171 Infectious disease: bacterial
   05134 Legionellosis
    103672248 (HSPA2)
  09172 Infectious disease: viral
   05162 Measles
    103672248 (HSPA2)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103672248 (HSPA2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:umr01009]
    103672248 (HSPA2)
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:umr03041]
    103672248 (HSPA2)
   03009 Ribosome biogenesis [BR:umr03009]
    103672248 (HSPA2)
   03110 Chaperones and folding catalysts [BR:umr03110]
    103672248 (HSPA2)
   04131 Membrane trafficking [BR:umr04131]
    103672248 (HSPA2)
   03051 Proteasome [BR:umr03051]
    103672248 (HSPA2)
   03029 Mitochondrial biogenesis [BR:umr03029]
    103672248 (HSPA2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103672248 (HSPA2)
Protein phosphatases and associated proteins [BR:umr01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-5
    PP5-interacting proteins
     103672248 (HSPA2)
Spliceosome [BR:umr03041]
 Complex B
  Other components
   Prp19 complex
    103672248 (HSPA2)
 Complex C
   Prp19-CDC5 complex
    103672248 (HSPA2)
Ribosome biogenesis [BR:umr03009]
 Eukaryotic type
  Pre-60S particles
   Export and cytoplasmic maturation factors
    103672248 (HSPA2)
Chaperones and folding catalysts [BR:umr03110]
 Heat shock proteins
  HSP70 / DNAK
   103672248 (HSPA2)
Membrane trafficking [BR:umr04131]
 Endocytosis
  Clathrin-mediated endocytosis
   Other core components
    103672248 (HSPA2)
 Autophagy
  Chaperone mediated autophagy (CMA)
   Chaperones
    103672248 (HSPA2)
Proteasome [BR:umr03051]
 Eukaryotic proteasome
  Assembling factors
   Other assembling factors
    103672248 (HSPA2)
Mitochondrial biogenesis [BR:umr03029]
 Mitochondrial protein import machinery
  Endoplasmic reticulum membrane and cytosol
   Other ER-memrane and cytosol factors
    103672248 (HSPA2)
Exosome [BR:umr04147]
 Exosomal proteins
  Proteins found in most exosomes
   103672248 (HSPA2)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: HSP70 MreB_Mbl FGGY_C BcrAD_BadFG DUF1464 DDR Zincin_2
Motif
Other DBs
NCBI-GeneID: 103672248
NCBI-ProteinID: XP_008699141
UniProt: A0A384CWF6
Position
Un
AA seq 636 aa AA seqDB search
MSARGPAIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQV
AMNPTNTIFDAKRLIGRKFEDATVQSDMKHWPFRVVSEGGKPKVQVEYKGEIKTFFPEEI
SSMVLTKMKEIAEAYLGGKVQSAVITVPAYFNDSQRQATKDAGTITGLNVLRIINEPTAA
AIAYGLDKKGCAGGEKNVLIFDLGGGTFDVSILTIEDGIFEVKSTAGDTHLGGEDFDNRM
VSHLAEEFKRKHKKDIGPNKRAVRRLRTACERAKRTLSSSTQASIEIDSLYEGVDFYTSI
TRARFEELNADLFRGTLEPVEKALRDAKLDKGQIQEIVLVGGSTRIPKIQKLLQDFFNGK
ELNKSINPDEAVAYGAAVQAAILIGDKSENVQDLLLLDVTPLSLGIETAGGVMTPLIKRN
TTIPTKQTQTFTTYSDNQSSVLVQVYEGERAMTKDNNLLGKFDLTGIPPAPRGVPQIEVT
FDIDANGILNVTAADKSTGKENKITITNDKGRLSKDDIDRMVQEAERYKSEDEANRDRVA
AKNAVESYTYNIKQTVEDEKLRGKISEQDKNKILDKCQEVINWLDRNQMAEKDEYEHKQK
ELERGCNPIISKLYQGGPGGGGGSGASGGPTIEEVD
NT seq 1911 nt NT seq  +upstreamnt  +downstreamnt
atgtctgcccgcggcccggctatcggcatcgacctgggcaccacctactcgtgcgtgggg
gtcttccaacatggcaaggtggagatcatcgccaacgaccagggcaaccgcaccaccccc
agctacgtggccttcaccgacaccgagcgcctgatcggcgacgccgccaagaaccaggtg
gccatgaaccccaccaacaccatcttcgacgccaagaggctgatcggacggaagttcgag
gacgccacggtgcagtcggacatgaaacactggccgttccgggtggtgagcgagggaggg
aagcccaaggtgcaggtggagtacaagggagagatcaagaccttcttcccagaggagatc
tcctccatggtcctcactaagatgaaagagatcgccgaagcctacctgggaggcaaggtg
cagagcgcggtcatcacggtgcctgcctatttcaatgactcgcagcgtcaggccaccaag
gacgcgggcaccatcacgggcctcaacgtgctgcgcatcatcaacgagcccaccgcggcg
gccattgcctacggtctggacaagaagggctgcgccggcggcgagaagaatgtgctcatc
tttgacttgggcggcggcaccttcgacgtgtccatcctgaccatcgaggacggcatcttc
gaggtgaagtccacggccggcgacacccacctgggcggcgaggacttcgacaaccgcatg
gtgagccacctggcggaggagttcaagcgcaagcacaagaaggacattgggcccaacaag
cgcgcagtgcggcgactgcgcaccgcctgcgagcgagccaagcgcaccttgagctcgtct
acgcaggcaagcatcgagatcgactcgctgtacgagggcgtggacttctacacgtccatc
acccgcgcccgcttcgaggagctcaatgctgacctgttccgcggaaccctggagccggtg
gagaaggcgctacgtgacgccaagctagacaagggccagatccaggagatcgtgctggtg
ggcggctccacccgcatccccaagatccagaagctgttgcaggattttttcaatggcaag
gagttgaacaagagcatcaaccccgacgaggcggtggcctacggggctgcggtgcaggcg
gccatcctcatcggggacaagtcagagaacgtgcaggacctgctgctgctcgacgtgacc
ccgttgtcgctgggcattgagacggctggcggcgtcatgaccccactcatcaagaggaac
accacgatccctaccaagcagacgcagaccttcaccacctactcagacaaccagagcagc
gtgctggtgcaggtgtacgagggcgaacgggccatgaccaaggacaataacctgctgggc
aagttcgacctgactgggattcccccggcgccccgcggggtcccccagatcgaggtcacc
ttcgatatcgacgccaatggcatcctcaacgtcaccgccgccgacaagagcaccggtaaa
gaaaacaaaatcaccattaccaacgacaagggtcgtctgagcaaggacgacattgatcga
atggtgcaggaggcagagcggtacaagtcggaagatgaggccaatcgcgaccgtgtcgcc
gccaaaaacgcggtggagtcctatacctacaacatcaagcagacggtggaagacgagaaa
ctgaggggcaagattagcgagcaggacaaaaacaagatcctcgacaagtgtcaggaggtg
atcaactggctcgaccgaaaccagatggcagagaaagatgagtatgaacacaagcagaaa
gagctcgaaagaggatgcaaccccatcatcagcaaactttaccaaggcggccctggcggc
ggtggcggttccggagcttccgggggaccgaccatcgaggaagtggactaa

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