KEGG   Ursus maritimus (polar bear): 103672390
Entry
103672390         CDS       T03271                                 
Symbol
F2
Name
(RefSeq) prothrombin
  KO
K01313  coagulation factor II (thrombin) [EC:3.4.21.5]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr04072  Phospholipase D signaling pathway
umr04080  Neuroactive ligand-receptor interaction
umr04610  Complement and coagulation cascades
umr04611  Platelet activation
umr04810  Regulation of actin cytoskeleton
umr05171  Coronavirus disease - COVID-19
umr05200  Pathways in cancer
Brite
KEGG Orthology (KO) [BR:umr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04072 Phospholipase D signaling pathway
    103672390 (F2)
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    103672390 (F2)
 09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    103672390 (F2)
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    103672390 (F2)
   04611 Platelet activation
    103672390 (F2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    103672390 (F2)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    103672390 (F2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:umr01002]
    103672390 (F2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:umr04147]
    103672390 (F2)
   00536 Glycosaminoglycan binding proteins [BR:umr00536]
    103672390 (F2)
Enzymes [BR:umr01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.21  Serine endopeptidases
    3.4.21.5  thrombin
     103672390 (F2)
Peptidases and inhibitors [BR:umr01002]
 Serine peptidases
  Family S1: chymotrypsin family
   103672390 (F2)
Exosome [BR:umr04147]
 Exosomal proteins
  Exosomal proteins of hepatic cells
   103672390 (F2)
Glycosaminoglycan binding proteins [BR:umr00536]
 Heparan sulfate / Heparin
  Coagulation and fibrinolysis
   103672390 (F2)
SSDB
Motif
Pfam: Trypsin Kringle Thrombin_light Gla DUF1986 Trypsin_2
Other DBs
NCBI-GeneID: 103672390
NCBI-ProteinID: XP_040494981
UniProt: A0A8M1GH29
Position
Unknown
AA seq 623 aa
MAHIRGLWVPGCLALAVLFSLVHSQHAVFLAPQQALSLLQRVRRANSGFLEELRKGNLER
ECVEEKCSYEEAFEALESSIATDVFWTKYTACESVRKPREKLTECLEGSCAEGLGMNYRG
NVSFTRSGIECQLWRSRYPHKPEINTTTHPGADLRENFCRNPDGSTTGPWCYTTDPTVRR
EECSIPVCGGGGVTVQLTPRSRGPTVNLPPSSEHCVPERGRYYQGRQAVTAHGSTCLAWA
SSQAKALSKDQDFNPAVPLVENFCRNPDGDEEGAWCYVSEGPGGFEYCDLDYCEEPVEEV
GDGLAEDPDAAIEGRTGDEEFQPFFNEKTFGAGEADCGLRPLFEKSLVKDKTEHELLESY
IDGRVVEGWDAEIGLAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE
NDLLVRIGKHSRTRYERSIEKISMLEKIYIHPRYNWRENLDRDIALLRLKKPIAFSNYIH
PVCLPDKDTAVRLLRAGYKGRVTGWGNLKEMWTSSVTEVQPSVLQVVNLPIVERPVCKAS
TRIRITDNMFCAGFKPNEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGEGCDRDGK
YGFYTHVFRLKKWIQKVIDQSGS
NT seq 1872 nt   +upstreamnt  +downstreamnt
atggcgcacatccgaggcctgtgggtacctggctgcctggccctagctgtcctgtttagc
cttgtgcacagccagcatgcagtgttcctggcccctcagcaagcattatcgttgctccag
cgggtccgacgcgccaacagtggcttcctggaggagttgcgcaaggggaacctggagcga
gagtgtgtggaagagaagtgcagctacgaagaggcctttgaggccctggagtcttccatc
gccacggatgtattctggaccaagtacacagcttgtgagtcggtgaggaaacctcgagaa
aagctcactgaatgtctggaaggtagctgtgctgaaggtctgggtatgaattaccgaggg
aacgtgagcttcacccggtcaggcatcgagtgtcagctctggaggagtcgctacccacat
aagcctgaaatcaacactaccacccaccctggggcggacctgcgggagaatttctgccgt
aacccggatggcagcaccactgggccctggtgctatacgacagaccccactgtgaggagg
gaggagtgcagcatccctgtctgcggcggggggggcgtcactgtgcagctgaccccacgc
tccagaggccccacggtgaatctgccaccttcatctgagcactgcgtccctgagcgtggc
cggtactaccagggtcgccaggcagtgaccgcacatgggtccacctgcctggcctgggcc
agcagtcaggctaaggcgctgagcaaggaccaggacttcaaccctgcggtgccgctggtg
gagaatttctgccgcaaccccgacggggacgaggagggcgcgtggtgttatgtgtcggag
gggcccggtggcttcgagtactgcgacctggactactgcgaggagcctgtggaagaggtg
ggcgacgggctggccgaggacccggacgcggccatcgagggacgcaccggcgacgaggag
ttccagcccttcttcaacgagaagactttcggcgccggggaggcagactgtgggctgcgg
cctctgtttgagaagtcgttggtgaaggacaaaacggaacacgagcttctggagtcctac
atcgacgggcgcgtcgtggagggttgggacgccgagattggcctcgcgccctggcaggtg
atgcttttccggaagagtccccaggagctgctttgtggggccagcctcatcagtgaccgc
tgggtccttactgctgcccactgtctcctgtacccaccttgggacaagaacttcaccgag
aatgatcttctggtgcgcattggcaagcactcccgcaccaggtatgagcgaagcattgag
aagatctccatgctggaaaagatctacatccaccccaggtacaactggagggagaacttg
gaccgtgacatagccctgctgaggctcaagaagcccatcgccttcagcaactacatccac
cctgtgtgcctgcctgacaaggacaccgcagtcagactgctccgcgcgggatacaaagga
cgggtgaccggttggggcaacctgaaggagatgtggacgtccagcgtgacagaggtgcag
cccagcgtcctgcaggtggtgaacctccccatcgtggagcggccggtgtgcaaggcctcc
actcggatccgcatcaccgacaacatgttctgtgctggtttcaagcccaatgaagggaaa
cgaggggatgcttgtgaaggcgacagcgggggaccgtttgtcatgaagagcccttttaac
aaccgctggtatcaaatgggcatcgtctcatggggtgaaggctgtgacagggatggaaaa
tatggcttctacacacacgtgttccgcctgaagaagtggatacagaaggtcattgatcag
tctggaagctag

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Ontology (5)   
   KEGG BRITE (5)   
Pathway (7)   
   KEGG PATHWAY (7)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (6)   
   Pfam (6)   
All databases (27)   

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