KEGG   Ursus maritimus (polar bear): 103674633
Entry
103674633         CDS       T03271                                 
Symbol
PIK3CG
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform isoform X1
  KO
K21289  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma [EC:2.7.1.153]
Organism
umr  Ursus maritimus (polar bear)
Pathway
umr00562  Inositol phosphate metabolism
umr01100  Metabolic pathways
umr04022  cGMP-PKG signaling pathway
umr04062  Chemokine signaling pathway
umr04072  Phospholipase D signaling pathway
umr04151  PI3K-Akt signaling pathway
umr04261  Adrenergic signaling in cardiomyocytes
umr04371  Apelin signaling pathway
umr04611  Platelet activation
umr04725  Cholinergic synapse
umr04921  Oxytocin signaling pathway
umr05132  Salmonella infection
umr05145  Toxoplasmosis
umr05167  Kaposi sarcoma-associated herpesvirus infection
Brite
KEGG Orthology (KO) [BR:umr00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    103674633 (PIK3CG)
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    103674633 (PIK3CG)
   04072 Phospholipase D signaling pathway
    103674633 (PIK3CG)
   04022 cGMP-PKG signaling pathway
    103674633 (PIK3CG)
   04151 PI3K-Akt signaling pathway
    103674633 (PIK3CG)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    103674633 (PIK3CG)
   04062 Chemokine signaling pathway
    103674633 (PIK3CG)
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    103674633 (PIK3CG)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    103674633 (PIK3CG)
  09156 Nervous system
   04725 Cholinergic synapse
    103674633 (PIK3CG)
 09160 Human Diseases
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    103674633 (PIK3CG)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    103674633 (PIK3CG)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    103674633 (PIK3CG)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:umr04131]
    103674633 (PIK3CG)
Enzymes [BR:umr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     103674633 (PIK3CG)
Membrane trafficking [BR:umr04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    103674633 (PIK3CG)
SSDB
Motif
Pfam: PIK3CG_ABD PI3_PI4_kinase PI3Ka PI3K_rbd PI3K_C2 DUF3244 DUF4135 Myc-LZ
Other DBs
NCBI-GeneID: 103674633
NCBI-ProteinID: XP_008701762
UniProt: A0A384D4P5 A0A452UV78
Position
Unknown
AA seq 1102 aa
MELENYEQPVVLREDNRRRRRRMKPRSSAASLSSMELIPIEFVLPTSQRHSKTPETALLH
VAGHGNVEQMKAQVWLRALETSVAADFYHRLGPDHFLLLYQKKGQWYEIYDKHQVVQTLD
CLRYWQVLHRSPGQIHVVQRRAPSDETLAFQRQLTALIGYDVTDVSNVHDNELEFTRRRL
VTPRMVEVAGRDPKLYAMHPWVTSKPLPEYLLKKITNNCIFIVIHRSTTSQTIKVSADDT
PGTILQSFFTKMAKKKSLLDIPESQNEQDFVLRVCGRDEYLVGETPIKNFQWVRHCLKNG
EEIHLVLDSPPDPALDEVRKEEWPLVDDCTGVTGYHEQLTIHGKDHESVFTVSLWDCDRK
FRVKIRGIDIPVLPRNADLTVFVEANIQHGQQVLCQRRTSPKPFTEEVLWNVWLEFSIQI
KDLPRGALLNLQIYCSKAPAPTGKGSADTPGSEGKGKAQLLYYVNLLLIDHRFLLRHGEY
VLHMWQISGKGEDQGSFNADKLTSATNPDKENSMSISILLDNYCHPIALPKHRPTPDPEG
DRVRAEMPNQLRKQLEAIIATDPLNPLTAEDKELLWHFRYESLKHPKAYPKLFSSVKWGQ
QEIVAKTYQLLARREVWDQSALDVGLTMQLLDCNFSDENVRAIAVQKLESLEDDDVLHYL
LQLVQAVKFEPYHDSALARFLLKRGLRNKRIGHFLFWFLRSEIAQSRHYQQRFAVLLEAY
LRGCGTAMLHDFSQQVHVIEMLQKVTIDIKSLSAEKYDVSSQVISQLKQKLENLQNSNLP
KSFRVPYDPGLKAGALVIEKCKVMASKKKPLWLEFKCADPTALSNETIGIIFKHGDDLRQ
DMLILQILRIMESIWETESLDLCLLPYGCISTGDKIGMIEIVKDATTIAKIQQSTVGNTG
AFKDEVLNHWLKEKCPIEEKFQAAVERFVYSCAGYCVATFVLGIGDRHNDNIMITETGNL
FHIDFGHILGNYKSFLGINKERVPFVLTPDFLFVMGTSGKKTSLHFQKFQDVCVKAYLAL
RHHTNLLIILFSMMLMTGMPQLTSKEDIEYIRDALTVGKNEEEAKKYFLDQIEVCRDKGW
TVQFNWFLHLVLGIKQGEKHSA
NT seq 3309 nt   +upstreamnt  +downstreamnt
atggagctggagaactatgagcagcccgtggttctgagagaggacaaccgccgccggcgc
cggaggatgaagccgcgcagctccgcggccagcctgtcctccatggagctcatccccatc
gagttcgtgctgcccaccagccagcgccacagcaagacccccgagacggcgctgctgcac
gtggccggccacggcaacgtggagcagatgaaggcccaagtgtggctgcgcgcgctggag
acgagcgtggcggcagacttctaccaccggctcggtccggaccacttcctcctgctctac
cagaagaagggccagtggtacgagatctacgacaagcaccaggtggtacagaccctggac
tgcctgcgctactggcaggtgctgcaccggagcccgggccagatccacgtggtgcagcgg
cgcgcgccctcggacgagacgctggccttccagcgccagctcaccgccctgattggctac
gacgtcaccgacgtcagcaacgtgcacgacaacgagctcgagttcacgcgccgccgcctg
gtcactccgcgcatggtcgaggtggccggccgcgaccccaagctctacgccatgcaccca
tgggtgacctccaagcccctcccggagtacctgctgaagaagattaccaacaactgcatc
ttcatcgtcattcaccgcagcaccaccagccagaccatcaaggtctcggccgacgacacc
ccgggcaccatcctccagagcttcttcaccaagatggccaagaagaagtctctgctggat
atccccgagagccaaaacgaacaggattttgtgctgcgcgtctgcggccgggacgagtac
ctggtaggcgaaacgcccatcaagaacttccagtgggtgaggcattgcctcaagaacgga
gaagagattcacctggtgctggactcgcctccagacccggccctggacgaggtgaggaaa
gaagagtggccgctggtggatgactgcacgggagtcaccggctaccacgagcagctgacc
atccacgggaaggaccacgagagtgtgttcaccgtgtccctgtgggactgcgaccggaag
ttcagggtcaaaatcagaggcattgatatccctgtgctgccccggaatgctgacctcaca
gtttttgtggaggccaacatccagcacgggcagcaggtcctgtgccaaaggagaaccagc
cccaaacccttcacggaggaggtgctctggaacgtgtggcttgagttcagtatccaaatc
aaagacttacccaggggggctctgctgaacctccagatctactgcagcaaagctccggcg
ccaaccggcaagggctccgcagacactccgggctcggagggcaaaggcaaagctcagctg
ctctattacgtgaacctgctgctgatcgaccaccgcttcctgctgcgccacggggagtac
gtgctccacatgtggcagatctcgggaaagggagaagaccaggggagcttcaatgccgac
aagctcacgtcggcgaccaacccagacaaggagaactccatgtccatctccattcttctg
gacaattactgtcacccaatcgccttgcccaagcatcggcccacccctgaccccgaaggg
gaccgggtgcgagcagagatgcccaatcagcttcggaagcaactggaggcgatcatagcc
acggatccacttaaccccctcacggcagaggacaaagaattgctctggcattttagatat
gaaagtcttaagcacccaaaggcctatcctaagctgtttagctccgtaaaatggggacag
caagaaattgtagccaaaacataccaactgttagccagacgggaggtctgggaccaaagt
gctttggatgttgggttaacgatgcaacttctggactgcaacttttcagacgaaaacgta
agagccatcgcagttcagaagctggagagcttggaggacgatgatgtcctgcattacctg
ctacagctggtccaggccgtgaaattcgagccatatcatgacagcgccctggcccgattt
ctgctgaaacgaggcttaaggaacaaaagaattggccatttcttgttttggttcttgaga
agtgagatagcccagtccagacactatcagcagaggttcgccgtgctcctggaggcctat
ctgaggggctgcggcacggccatgctgcacgacttctcccaacaagttcacgtgatcgag
atgctgcagaaggtcaccattgatattaaatcgctctctgcagaaaagtatgacgtcagt
tcccaagttatttcacaacttaagcaaaagctcgaaaacctgcagaattcaaatctccca
aagagctttagagtgccgtacgatcctggactgaaggcaggagcgctagtgattgaaaaa
tgtaaagtgatggcctccaagaaaaagcccctgtggcttgagtttaaatgtgctgaccct
acagccctatccaatgaaacgatcggaattatctttaaacacggtgatgatctgcgccaa
gacatgctcattttacagattctgcgaatcatggaatccatttgggagactgaatctttg
gatctgtgcctcctgccatatggttgcatttcaactggggacaaaataggaatgatcgag
atcgtgaaagatgccacaacaattgccaaaattcagcaaagcacagtgggcaacacgggc
gcgttcaaagatgaagtcctgaatcactggctcaaagaaaaatgccctattgaagaaaag
tttcaggcagcagtggagagatttgtttattcctgtgctggctactgtgtggctaccttt
gttcttggaataggcgacaggcacaacgacaatattatgatcacagagacaggaaaccta
tttcatattgactttggacacattcttgggaattacaaaagtttcctgggcattaataaa
gaaagagtgccgtttgtgctaaccccagacttcctgtttgtgatgggaacttctggaaag
aagacaagcctacacttccagaaatttcaggacgtctgcgtcaaggcttacctagccctt
cgtcaccacacaaatctgctcatcatcctgttctccatgatgctgatgacgggaatgccc
cagttaacaagcaaagaagacatcgaatatattcgggatgccctcacagtggggaagaac
gaggaggaagctaagaagtattttcttgatcagatcgaagtttgcagggacaaaggatgg
accgtgcagtttaactggttcctgcaccttgttctgggcatcaaacaaggagagaaacat
tcagcctaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (14)   
   KEGG PATHWAY (14)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (7)   
   UniProt (2)   
   RefSeq(pep) (5)   
DNA sequence (5)   
   RefSeq(nuc) (5)   
Protein domain (8)   
   Pfam (8)   
All databases (48)   

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