KEGG T03271: 103680750

Ursus maritimus (polar bear): 103680750

Entry

103680750         CDS       T03271

Symbol

PFKL

Name

(RefSeq) ATP-dependent 6-phosphofructokinase, liver type isoform X1

K00850

6-phosphofructokinase 1 [EC:2.7.1.11]

Organism

umr Ursus maritimus (polar bear)

Pathway

umr00010

Glycolysis / Gluconeogenesis

umr00030

Pentose phosphate pathway

umr00051

Fructose and mannose metabolism

umr00052

Galactose metabolism

umr01100

Metabolic pathways

umr01200

Carbon metabolism

umr01230

Biosynthesis of amino acids

umr03018

RNA degradation

umr04066

HIF-1 signaling pathway

umr04152

AMPK signaling pathway

umr04919

Thyroid hormone signaling pathway

umr04922

Glucagon signaling pathway

umr05230

Central carbon metabolism in cancer

Module

umr_M00001

Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate

Brite

KEGG Orthology (KO) [BR:umr00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    103680750 (PFKL)
   00030 Pentose phosphate pathway
    103680750 (PFKL)
   00051 Fructose and mannose metabolism
    103680750 (PFKL)
   00052 Galactose metabolism
    103680750 (PFKL)
09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   03018 RNA degradation
    103680750 (PFKL)
09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    103680750 (PFKL)
   04152 AMPK signaling pathway
    103680750 (PFKL)
09150 Organismal Systems
  09152 Endocrine system
   04922 Glucagon signaling pathway
    103680750 (PFKL)
   04919 Thyroid hormone signaling pathway
    103680750 (PFKL)
09160 Human Diseases
  09161 Cancer: overview
   05230 Central carbon metabolism in cancer
    103680750 (PFKL)
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:umr01009]
    103680750 (PFKL)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:umr03019]
    103680750 (PFKL)
Enzymes [BR:umr01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.11  6-phosphofructokinase
     103680750 (PFKL)
Protein phosphatases and associated proteins [BR:umr01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     103680750 (PFKL)
Messenger RNA biogenesis [BR:umr03019]
Prokaryotic type
  Bacterial mRNA degradation factors
   RNA degradosome components
    Other RNA degradosome components
     103680750 (PFKL)

SSDB

Motif

Pfam:

PFK

Other DBs

NCBI-GeneID:

103680750

NCBI-ProteinID:

XP_040477760

UniProt:

A0A8M1F6I9

Position

Unknown

AA seq 780 aa
MATVDLEKLRMSGAGKAIGVLTSGGDAQGMNAAVRAVTRMGLYVGAKVFLIYEGYEGLVE
GGENIKQANWLSVSNIIQLGGTVIGSARCKAFTTREGRLAAAYNLVQRGITNLCVIGGDG
SLTGANIFRSEWGSLLEELVGAGKISESTAQTYSHLSIAGLVGSIDNDFCGTDMTIGTDS
ALHRIMEVIDAITTTAQSHQRTFVLEVMGRHCGYLALVSALASGADWLFIPEAPPEDGWE
NFMCERLGETRSRGSRLNIIIIAEGAIDRNGKPISSRYVKDLVVQRLGFDTRVTVLGHVQ
RGGTPSAFDRILSSKMGMEAVMALLEATPDTQACVVSLSGNQSVRLPLMECVQVTKEVQK
AMDEKRFDEAIQLRGRSFENNWNIYKLLAHQKVSKEKTNFSLAILNVGAPAAGMNAAVRS
AVRSGISQGHTVYVVHDGFEGLAKGQVQEVSWHDVAGWLGRGGSMLGTKRTLPKSYMEKI
VGNIRTHNIHALLVIGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGTDYSLG
SDTAVNAAMESCDRIKQSASGTKRRVFIVETMGGYCGYLATVTGIAVGADAAYVFEDPFN
IQDLKANVEHMTEKMKTEIQRGLVLRNEKCHEHYTTEFLYNLYSSEGKGVFDCRTNVLGH
LQQGGAPTPFDRNYGTKLGVKAMLWMSEKLRAVYRNGRVFANAPDSACVIGLQKKAVAFS
PVTELKKDTDFEHRMPREQWWLNLRLMLKMLAHYRISMADYVSGELEHVTRRSLSIDKGF

NT seq 2343 nt +upstreamnt +downstreamnt
atggccaccgtggacctggagaagctgcgaatgtccggggccggcaaggccatcggcgtg
ctgaccagcggcggagatgctcaaggtatgaatgcggctgtcagagctgtgacgcgcatg
ggcctttatgtgggagccaaagtcttcctcatctacgagggctatgagggtctcgtggaa
ggaggcgagaacatcaagcaggccaattggctcagtgtctccaacatcatccagctgggt
ggcaccgtcatcggcagcgcgcgctgcaaggccttcaccactcgggagggacgcctggca
gcggcctacaacctcgtacagcgtggcatcaccaacctgtgcgtcatcggcggggacggc
agcctcacgggcgccaacatcttccgtagcgagtggggcagcctgctggaggagctggtg
ggggcaggcaagatctcggagagcacggcacagacgtactcgcatctgagcatcgcgggg
ctggtgggctccatcgacaatgacttctgcggcactgacatgaccatcggcacggactcg
gccctgcaccgcatcatggaggtcattgacgccatcaccaccactgcccagagccaccag
aggacctttgtgctggaggtgatgggacggcactgcgggtacctggcgctggtgtccgcc
ctggcctcaggggccgactggctgttcattcctgaggcgccccccgaggatggctgggag
aacttcatgtgcgagcggctgggggagactcggagcagggggtcccgacttaacatcatc
atcattgccgagggcgccattgaccgcaacgggaagcccatctcctcccgctacgtgaag
gatctggttgtccagaggctgggtttcgacacgcgtgtgactgtgctgggccacgtgcag
aggggagggaccccttcggcgttcgaccgcatcctgagcagcaagatgggcatggaggcg
gtcatggcgctgctggaggccacaccggacacgcaggcctgcgtggtcagcctctcgggg
aaccagtccgtgcggctgcccctcatggagtgtgtgcaggtgacaaaggaggtgcagaag
gccatggatgagaagaggttcgacgaggccatccagctccgcggcaggagctttgagaac
aactggaacatttacaagctgcttgcacaccagaaggtctccaaagagaagaccaacttc
tccctggccatcctgaacgtgggggccccggcggctggcatgaacgcggcggtgcgctcg
gcggtgcggtccggcatctcccagggccacacagtgtatgtcgtgcacgatggcttcgaa
ggcctggccaagggtcaggtacaagaagttagttggcatgacgtggctggctggcttggc
cgcggcggctccatgctggggaccaagaggacgctgcccaagagctacatggagaaaatc
gtgggaaacatccgtacccacaatatccacgccctgctggtcatcggtggctttgaggcc
tacgagggggtgctgcagctggtggaggcgcgcgggcgctacgaggagctgtgcattgtc
atgtgcgtcatccccgccaccatcagcaacaacgtcccgggcaccgactatagcctgggt
tccgacaccgccgtcaacgccgccatggagagctgtgaccgcatcaagcagtcagcctcg
gggactaagcgccgtgtgttcatcgtggagaccatggggggctactgcggctacctggcc
acggtgaccggcatcgcggtgggcgccgacgccgcctacgtctttgaggaccctttcaat
atccaagacttaaaagccaacgtggagcacatgacggagaagatgaagacggagatccag
aggggcctcgtgctccgaaacgagaagtgccacgaacactacaccacggagttcctgtat
aacctgtactcctccgaggggaagggcgtgtttgactgtcgcaccaacgtcctgggccac
ctgcagcagggcggggctccgaccccctttgaccggaactatgggaccaagctcggggtg
aaggccatgctctggatgtcggagaagctgcgggcggtctaccgcaatgggcgtgtgttt
gccaacgcccccgattcggcctgcgtcatcggcctgcagaagaaggcggtggccttcagc
cccgtcaccgagctcaagaaggacacggactttgagcaccgcatgccccgggagcagtgg
tggctgaacctgcggctcatgctgaagatgctggcgcattaccgcatcagcatggccgac
tacgtgtccggggagctggagcacgtcacccgccgcagcctcagcatcgacaagggcttc
tga

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