ID A0A010SWS0_PSEFL Unreviewed; 122 AA.
AC A0A010SWS0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 33.
DE RecName: Full=Cyclic diguanosine monophosphate-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE Short=c-di-GMP-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE AltName: Full=Pilz domain-containing protein {ECO:0000256|PIRNR:PIRNR028141};
GN ORFNames=HK44_026875 {ECO:0000313|EMBL:EXF95248.1};
OS Pseudomonas fluorescens HK44.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=1042209 {ECO:0000313|EMBL:EXF95248.1, ECO:0000313|Proteomes:UP000022611};
RN [1] {ECO:0000313|EMBL:EXF95248.1, ECO:0000313|Proteomes:UP000022611}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HK44 {ECO:0000313|EMBL:EXF95248.1,
RC ECO:0000313|Proteomes:UP000022611};
RX PubMed=21742869; DOI=10.1128/JB.05530-11;
RA Chauhan A., Layton A.C., Williams D.E., Smartt A.E., Ripp S.,
RA Karpinets T.V., Brown S.D., Sayler G.S.;
RT "Draft genome sequence of the polycyclic aromatic hydrocarbon-degrading,
RT genetically engineered bioluminescent bioreporter Pseudomonas fluorescens
RT HK44.";
RL J. Bacteriol. 193:5009-5010(2011).
CC -!- FUNCTION: Binds the second messenger bis-(3'-5') cyclic dimeric
CC guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per
CC monomer. May play a role in bacterial second-messenger regulated
CC processes. Binding to c-di-GMP induces a conformational change of the
CC C- and N-termini resulting in the exposure of a highly negative surface
CC on one side of the protein to a possible effector protein.
CC {ECO:0000256|PIRNR:PIRNR028141}.
CC -!- SUBUNIT: Monomer in both c-di-GMP-bound and free forms.
CC {ECO:0000256|PIRNR:PIRNR028141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXF95248.1}.
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DR EMBL; AFOY02000008; EXF95248.1; -; Genomic_DNA.
DR RefSeq; WP_019691595.1; NZ_AFOY02000008.1.
DR AlphaFoldDB; A0A010SWS0; -.
DR PATRIC; fig|1042209.11.peg.1944; -.
DR eggNOG; ENOG5032YUI; Bacteria.
DR HOGENOM; CLU_146776_0_1_6; -.
DR OrthoDB; 5298508at2; -.
DR Proteomes; UP000022611; Unassembled WGS sequence.
DR GO; GO:0035438; F:cyclic-di-GMP binding; IEA:InterPro.
DR Gene3D; 2.40.10.220; predicted glycosyltransferase like domains; 1.
DR InterPro; IPR027021; C-di-GMP_BP_PA4608.
DR InterPro; IPR009875; PilZ_domain.
DR Pfam; PF07238; PilZ; 1.
DR PIRSF; PIRSF028141; C-di-GMP_BP_PA4608; 1.
DR SUPFAM; SSF141371; PilZ domain-like; 1.
PE 4: Predicted;
KW c-di-GMP {ECO:0000256|PIRNR:PIRNR028141};
KW Nucleotide-binding {ECO:0000256|PIRNR:PIRNR028141};
KW Reference proteome {ECO:0000313|Proteomes:UP000022611}.
FT DOMAIN 7..103
FT /note="PilZ"
FT /evidence="ECO:0000259|Pfam:PF07238"
SQ SEQUENCE 122 AA; 14243 MW; 277DDC857AF14D14 CRC64;
MRDHPANRRR FKRIAFDAIT ELSQGEHRWP VKLLDLSLKG LLIERPEPWL GDKEKMFSVD
IHLSKDTEIR MDVQLSHDNN RQLGFVCRYI GLESVSSLRR LIELNTGDQA ELERELGALI
HI
//