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Database: UniProt
Entry: A0A010SWS0_PSEFL
LinkDB: A0A010SWS0_PSEFL
Original site: A0A010SWS0_PSEFL 
ID   A0A010SWS0_PSEFL        Unreviewed;       122 AA.
AC   A0A010SWS0;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 33.
DE   RecName: Full=Cyclic diguanosine monophosphate-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE            Short=c-di-GMP-binding protein {ECO:0000256|PIRNR:PIRNR028141};
DE   AltName: Full=Pilz domain-containing protein {ECO:0000256|PIRNR:PIRNR028141};
GN   ORFNames=HK44_026875 {ECO:0000313|EMBL:EXF95248.1};
OS   Pseudomonas fluorescens HK44.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1042209 {ECO:0000313|EMBL:EXF95248.1, ECO:0000313|Proteomes:UP000022611};
RN   [1] {ECO:0000313|EMBL:EXF95248.1, ECO:0000313|Proteomes:UP000022611}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HK44 {ECO:0000313|EMBL:EXF95248.1,
RC   ECO:0000313|Proteomes:UP000022611};
RX   PubMed=21742869; DOI=10.1128/JB.05530-11;
RA   Chauhan A., Layton A.C., Williams D.E., Smartt A.E., Ripp S.,
RA   Karpinets T.V., Brown S.D., Sayler G.S.;
RT   "Draft genome sequence of the polycyclic aromatic hydrocarbon-degrading,
RT   genetically engineered bioluminescent bioreporter Pseudomonas fluorescens
RT   HK44.";
RL   J. Bacteriol. 193:5009-5010(2011).
CC   -!- FUNCTION: Binds the second messenger bis-(3'-5') cyclic dimeric
CC       guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per
CC       monomer. May play a role in bacterial second-messenger regulated
CC       processes. Binding to c-di-GMP induces a conformational change of the
CC       C- and N-termini resulting in the exposure of a highly negative surface
CC       on one side of the protein to a possible effector protein.
CC       {ECO:0000256|PIRNR:PIRNR028141}.
CC   -!- SUBUNIT: Monomer in both c-di-GMP-bound and free forms.
CC       {ECO:0000256|PIRNR:PIRNR028141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EXF95248.1}.
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DR   EMBL; AFOY02000008; EXF95248.1; -; Genomic_DNA.
DR   RefSeq; WP_019691595.1; NZ_AFOY02000008.1.
DR   AlphaFoldDB; A0A010SWS0; -.
DR   PATRIC; fig|1042209.11.peg.1944; -.
DR   eggNOG; ENOG5032YUI; Bacteria.
DR   HOGENOM; CLU_146776_0_1_6; -.
DR   OrthoDB; 5298508at2; -.
DR   Proteomes; UP000022611; Unassembled WGS sequence.
DR   GO; GO:0035438; F:cyclic-di-GMP binding; IEA:InterPro.
DR   Gene3D; 2.40.10.220; predicted glycosyltransferase like domains; 1.
DR   InterPro; IPR027021; C-di-GMP_BP_PA4608.
DR   InterPro; IPR009875; PilZ_domain.
DR   Pfam; PF07238; PilZ; 1.
DR   PIRSF; PIRSF028141; C-di-GMP_BP_PA4608; 1.
DR   SUPFAM; SSF141371; PilZ domain-like; 1.
PE   4: Predicted;
KW   c-di-GMP {ECO:0000256|PIRNR:PIRNR028141};
KW   Nucleotide-binding {ECO:0000256|PIRNR:PIRNR028141};
KW   Reference proteome {ECO:0000313|Proteomes:UP000022611}.
FT   DOMAIN          7..103
FT                   /note="PilZ"
FT                   /evidence="ECO:0000259|Pfam:PF07238"
SQ   SEQUENCE   122 AA;  14243 MW;  277DDC857AF14D14 CRC64;
     MRDHPANRRR FKRIAFDAIT ELSQGEHRWP VKLLDLSLKG LLIERPEPWL GDKEKMFSVD
     IHLSKDTEIR MDVQLSHDNN RQLGFVCRYI GLESVSSLRR LIELNTGDQA ELERELGALI
     HI
//
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