ID A0A011NSC3_9PROT Unreviewed; 738 AA.
AC A0A011NSC3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 28.
DE SubName: Full=Bicarbonate transporter BicA {ECO:0000313|EMBL:EXI67425.1};
GN Name=bicA_1 {ECO:0000313|EMBL:EXI67425.1};
GN ORFNames=AW08_01981 {ECO:0000313|EMBL:EXI67425.1};
OS Candidatus Accumulibacter adjunctus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=1454001 {ECO:0000313|EMBL:EXI67425.1, ECO:0000313|Proteomes:UP000020218};
RN [1] {ECO:0000313|EMBL:EXI67425.1, ECO:0000313|Proteomes:UP000020218}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-12 {ECO:0000313|Proteomes:UP000020218};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXI67425.1}.
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DR EMBL; JFAX01000010; EXI67425.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A011NSC3; -.
DR STRING; 1454001.AW08_01981; -.
DR PATRIC; fig|1454001.3.peg.2021; -.
DR Proteomes; UP000020218; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd00038; CAP_ED; 1.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 2.60.120.10; Jelly Rolls; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR000595; cNMP-bd_dom.
DR InterPro; IPR018490; cNMP-bd_dom_sf.
DR InterPro; IPR014710; RmlC-like_jellyroll.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR PANTHER; PTHR43310; SULFATE TRANSPORTER YBAR-RELATED; 1.
DR PANTHER; PTHR43310:SF1; SULFATE TRANSPORTER YBAR-RELATED; 1.
DR Pfam; PF00027; cNMP_binding; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SMART; SM00100; cNMP; 1.
DR SUPFAM; SSF51206; cAMP-binding domain-like; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50042; CNMP_BINDING_3; 1.
DR PROSITE; PS50801; STAS; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000020218};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 45..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 74..93
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 99..120
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 132..154
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 174..196
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 203..221
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 267..292
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..377
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 397..428
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 457..574
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
FT DOMAIN 599..703
FT /note="Cyclic nucleotide-binding"
FT /evidence="ECO:0000259|PROSITE:PS50042"
SQ SEQUENCE 738 AA; 79248 MW; 7668E0929FE2FF91 CRC64;
MELAMTVKND KLVGDFWGGL AAMLVALPSA IAFGVTIYAS IGPAYAGLGA LAGILGATAL
GLVAPALGGT NRLITAPCAP AAAVLSAFAI ELVRQDVDPV FIVLMLTALG LVAGVIQLLL
GFMGIGSLIK YIPFPVVSGY LTGVGLIIIG SQIPKFLGVF GNVPLWRTLI SPDSWQWQSA
LIGGVTALVM VGAPVLTRAV PAAILGLLAG IATYFGLAHF VDESLLVLEG NKMIIGPLGG
SASSMLDAIT GRWRDIGELK LSQIGNLMGT ALTLAVLLSI DTLKTAVVLD ALTRSRHDSN
RELVAQGAAN VVSACAGGMP GAGQMGATLV NLASGGQTRV SGIIEGVLAL VAFLALGAFI
AWIPVAALAG ILLVVGVRMI DRHSLHLLQS PWTMLDFVVI VVVVIVALAY SLIAASAVGI
ALAMFLFIRE QLGSTIIRNK VDGGNRFSKR VRLGHEMDLL ERRGEQTIML ELQGSLFFGT
KDQLFSALEP ELGKRQYVLL DMRRVQSVDV TAVHLLSQIR DSLSERGAFL LFSSLTHTLP
NGRNIAELFA QMDLTNDNPQ VKVFQEMDDA VEWIEDQVLG ETAQRSAELP PLEVWEMEIF
RDVKEDALVD LVERLERRVV PRDERLFSIG DAADQLFLIR KGAVRISVPV PGTSLSRHRL
TYGRGDFVGG MSFITHAARF STDATATEDS EVYVLRREDF EILREQHRRL AFQLIEGVAR
VLAFRLGYAD RELLAMQE
//
