ID A0A011NW20_9PROT Unreviewed; 351 AA.
AC A0A011NW20;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=DNA ligase {ECO:0000313|EMBL:EXI68820.1};
DE EC=6.5.1.2 {ECO:0000313|EMBL:EXI68820.1};
GN Name=ligA {ECO:0000313|EMBL:EXI68820.1};
GN ORFNames=AW07_04318 {ECO:0000313|EMBL:EXI68820.1};
OS Candidatus Accumulibacter sp. SK-11.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Candidatus Accumulibacter.
OX NCBI_TaxID=1454000 {ECO:0000313|EMBL:EXI68820.1, ECO:0000313|Proteomes:UP000020226};
RN [1] {ECO:0000313|EMBL:EXI68820.1, ECO:0000313|Proteomes:UP000020226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SK-11 {ECO:0000313|Proteomes:UP000020226};
RA Skennerton C.T., Barr J.J., Slater F.R., Bond P.L., Tyson G.W.;
RT "Expanding our view of genomic diversity in Candidatus Accumulibacter
RT clades.";
RL Submitted (FEB-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXI68820.1}.
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DR EMBL; JFAW01000046; EXI68820.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A011NW20; -.
DR STRING; 1454000.AW07_04318; -.
DR PATRIC; fig|1454000.3.peg.3504; -.
DR Proteomes; UP000020226; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0003911; F:DNA ligase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0006260; P:DNA replication; IEA:InterPro.
DR CDD; cd17748; BRCT_DNA_ligase_like; 1.
DR Gene3D; 6.20.10.30; -; 1.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 2.
DR Gene3D; 3.40.50.10190; BRCT domain; 1.
DR Gene3D; 2.40.50.140; Nucleic acid-binding proteins; 1.
DR InterPro; IPR001357; BRCT_dom.
DR InterPro; IPR036420; BRCT_dom_sf.
DR InterPro; IPR041663; DisA/LigA_HHH.
DR InterPro; IPR033136; DNA_ligase_CS.
DR InterPro; IPR013840; DNAligase_N.
DR InterPro; IPR003583; Hlx-hairpin-Hlx_DNA-bd_motif.
DR InterPro; IPR012340; NA-bd_OB-fold.
DR InterPro; IPR004150; NAD_DNA_ligase_OB.
DR InterPro; IPR010994; RuvA_2-like.
DR InterPro; IPR004149; Znf_DNAligase_C4.
DR PANTHER; PTHR23389; CHROMOSOME TRANSMISSION FIDELITY FACTOR 18; 1.
DR PANTHER; PTHR23389:SF9; DNA LIGASE; 1.
DR Pfam; PF00533; BRCT; 1.
DR Pfam; PF03120; DNA_ligase_OB; 1.
DR Pfam; PF03119; DNA_ligase_ZBD; 1.
DR Pfam; PF12826; HHH_2; 1.
DR Pfam; PF14520; HHH_5; 1.
DR SMART; SM00292; BRCT; 1.
DR SMART; SM00278; HhH1; 4.
DR SMART; SM00532; LIGANc; 1.
DR SUPFAM; SSF52113; BRCT domain; 1.
DR SUPFAM; SSF50249; Nucleic acid-binding proteins; 1.
DR SUPFAM; SSF47781; RuvA domain 2-like; 1.
DR PROSITE; PS50172; BRCT; 1.
DR PROSITE; PS01056; DNA_LIGASE_N2; 1.
PE 4: Predicted;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW Ligase {ECO:0000313|EMBL:EXI68820.1};
KW Magnesium {ECO:0000256|ARBA:ARBA00022842};
KW Manganese {ECO:0000256|ARBA:ARBA00023211};
KW Reference proteome {ECO:0000313|Proteomes:UP000020226}.
FT DOMAIN 268..351
FT /note="BRCT"
FT /evidence="ECO:0000259|PROSITE:PS50172"
SQ SEQUENCE 351 AA; 37588 MW; 1D4B5BCD6EB2AB10 CRC64;
MLDISLQVGR TGALTPVARL APVFVGGVTV TNATLHNEDE IRRKDVRVGD TVVVRRAGDV
IPEVVRVLPE KRPPAASAFV MAATCPVCGS QVVRQQDEAV ARCSGGLYCP AQRRQALLHF
ASRRAMDIEG LGERLVEQLV EHDVVRTPAD LYRLGLLALV QLERMAEKSA GNLLLAIERS
RQTTLARFIY ALGIRNVGEA TARDLARHFG SLDRLLAADE AQLLQVPDVG PIVAQSIRQF
LGEPHNREVI EQLRAAGVAW SEDEVPAAAL GAVAGRTFVL TGTLPSLSRD AARQMLEAAG
GKVSAAVSKK TDFVVAGADA GSKLQRAQEL GVPIIDETQM LALLDGRQVA P
//
