ID A0A011RMU5_9LACT Unreviewed; 328 AA.
AC A0A011RMU5;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 24-JAN-2024, entry version 23.
DE SubName: Full=Branched-chain alpha-keto acid dehydrogenase, E1 component, beta subunit {ECO:0000313|EMBL:EXJ23233.1};
DE EC=1.2.4.4 {ECO:0000313|EMBL:EXJ23233.1};
GN ORFNames=ADIAL_1380 {ECO:0000313|EMBL:EXJ23233.1};
OS Alkalibacterium sp. AK22.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alkalibacterium.
OX NCBI_TaxID=1229520 {ECO:0000313|EMBL:EXJ23233.1, ECO:0000313|Proteomes:UP000020164};
RN [1] {ECO:0000313|EMBL:EXJ23233.1, ECO:0000313|Proteomes:UP000020164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK22 {ECO:0000313|Proteomes:UP000020164};
RA Singh A., Pinnaka A.K.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=thiamine diphosphate; Xref=ChEBI:CHEBI:58937;
CC Evidence={ECO:0000256|ARBA:ARBA00001964};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ23233.1}.
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DR EMBL; JANL01000032; EXJ23233.1; -; Genomic_DNA.
DR RefSeq; WP_034301671.1; NZ_JANL01000032.1.
DR AlphaFoldDB; A0A011RMU5; -.
DR STRING; 1229520.ADIAL_1380; -.
DR PATRIC; fig|1229520.3.peg.1345; -.
DR eggNOG; COG0022; Bacteria.
DR OrthoDB; 9771835at2; -.
DR Proteomes; UP000020164; Unassembled WGS sequence.
DR GO; GO:0003863; F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity; IEA:UniProtKB-EC.
DR CDD; cd07036; TPP_PYR_E1-PDHc-beta_like; 1.
DR Gene3D; 3.40.50.920; -; 1.
DR Gene3D; 3.40.50.970; -; 1.
DR InterPro; IPR029061; THDP-binding.
DR InterPro; IPR009014; Transketo_C/PFOR_II.
DR InterPro; IPR005475; Transketolase-like_Pyr-bd.
DR InterPro; IPR033248; Transketolase_C.
DR PANTHER; PTHR42980:SF1; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA, MITOCHONDRIAL; 1.
DR PANTHER; PTHR42980; 2-OXOISOVALERATE DEHYDROGENASE SUBUNIT BETA-RELATED; 1.
DR Pfam; PF02779; Transket_pyr; 1.
DR Pfam; PF02780; Transketolase_C; 1.
DR SMART; SM00861; Transket_pyr; 1.
DR SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 1.
DR SUPFAM; SSF52922; TK C-terminal domain-like; 1.
PE 4: Predicted;
KW Oxidoreductase {ECO:0000313|EMBL:EXJ23233.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000020164}.
FT DOMAIN 4..180
FT /note="Transketolase-like pyrimidine-binding"
FT /evidence="ECO:0000259|SMART:SM00861"
SQ SEQUENCE 328 AA; 36047 MW; 22DE1BF8B515E0AE CRC64;
MAMMTYLEAI KKGIEEEMAR DERVVIFGED VGGVKGGVFG VTKGLAEKFG EERCFNTPLT
EGQIGGLAVG LGLVGYRPIG EFQFADYILP AVNQLISEAS RMRYRTKGDW TAPVVYRAPY
GGGVRGGLYH SQSTEKVLFG QPGLRIVTPS SPHDAKGLIK AAIRCDDPVL FYEHKRLYRL
LKEDVPEEDY TVPLDKANVV REGEDLTVIA YGMVLNHALK AAETLSEEGI EAEIVDVRSL
YPLDKETLVK AAKKTGKVLL VTEDNLEGSI MSEISAVIAE EALFDLDAPI RRLAGPDSPS
MPYAIALERA FLVDEDKVRT AMRELAEF
//
