ID A0A011SJW1_9LACT Unreviewed; 897 AA.
AC A0A011SJW1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 45.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ADIAL_0086 {ECO:0000313|EMBL:EXJ24347.1};
OS Alkalibacterium sp. AK22.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Carnobacteriaceae;
OC Alkalibacterium.
OX NCBI_TaxID=1229520 {ECO:0000313|EMBL:EXJ24347.1, ECO:0000313|Proteomes:UP000020164};
RN [1] {ECO:0000313|EMBL:EXJ24347.1, ECO:0000313|Proteomes:UP000020164}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=AK22 {ECO:0000313|Proteomes:UP000020164};
RA Singh A., Pinnaka A.K.;
RL Submitted (JAN-2014) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EXJ24347.1}.
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DR EMBL; JANL01000006; EXJ24347.1; -; Genomic_DNA.
DR RefSeq; WP_051503617.1; NZ_JANL01000006.1.
DR AlphaFoldDB; A0A011SJW1; -.
DR STRING; 1229520.ADIAL_0086; -.
DR PATRIC; fig|1229520.3.peg.86; -.
DR eggNOG; COG2205; Bacteria.
DR OrthoDB; 9806130at2; -.
DR Proteomes; UP000020164; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0034220; P:monoatomic ion transmembrane transport; IEA:UniProtKB-KW.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd01987; USP_OKCHK; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 1.20.120.620; Backbone structure of the membrane domain of e. Coli histidine kinase receptor kdpd; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.620; HUPs; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR038318; KdpD_sf.
DR InterPro; IPR025201; KdpD_TM.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014729; Rossmann-like_a/b/a_fold.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR InterPro; IPR003852; Sig_transdc_His_kinase_KdpD_N.
DR InterPro; IPR006016; UspA.
DR PANTHER; PTHR45569; SENSOR PROTEIN KDPD; 1.
DR PANTHER; PTHR45569:SF1; SENSOR PROTEIN KDPD; 1.
DR Pfam; PF13493; DUF4118; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF02702; KdpD; 1.
DR Pfam; PF00582; Usp; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF52402; Adenine nucleotide alpha hydrolases-like; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ion channel {ECO:0000313|EMBL:EXJ24347.1};
KW Ion transport {ECO:0000313|EMBL:EXJ24347.1};
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:EXJ24347.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000020164};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000313|EMBL:EXJ24347.1};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000313|EMBL:EXJ24347.1};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 392..414
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 420..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..461
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 467..487
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 675..892
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 897 AA; 100197 MW; B6C038CFC49CBB0F CRC64;
MRKESDNMHV YSDIRSRSSS GGGQLKIYLG YAAGVGKTYA MLKDAQDLIK EGVDIVAGYV
EPHDRPETSA LLEGLEHIPP LAVPYKTMTV KEFDLDAALQ RKPQVILVDE FAHTNVSGVR
HAKRYQDIQE LLRAGIDVYT TVNIQHIESL NDQIAAITGV SVRERIPDKI FDLAQQIEVV
DIEPKDLLDR LNKGRIYKEN QVPKALKNFF TLEKLIALRE IALRHAADHV NRIALDNIEL
ARKYNTATSE HILVCLSASP SNTKVIRTAS RMAKAFNAKF TALYVESTND QYQDSKKEAS
LRAAMHLADQ LGAEIVTVYG NDIVRQIFEY ARASRVTKIV VGRSVQSKRW PRKRSIVDKL
SDNEVDIDIH VIPDSQSTPQ TEKKNILSRI QFSLSETFLT LFILTITTLI GTLFDNLNFS
EANIITVYIL GVLLIAMLSR QRSTSLLSSG LAVLAFNFFF TEPRFTFVVY DLGYITTFII
MLAAGLVTST LTQQVQMQAE ESSRKAYYTE ILFQTSKKLQ SASTRQEIID RTAEQITKLL
DLPLIIYPSS NGALLEPLTY DTPRKATDWP TLLSPNELAV ARWAFTNNQQ AGSNTQTLSS
SQGSYLVIRG AQGPLGVLGI VADESKKLQK FEKNLLIAIL DECSLAWEKN DSNELQKELH
AQIQKEKLRS NLLRAISHDL RVPLTSISGN STLLINNHKQ LDEEKQLALY SNIYTDSIWL
INLVENLLSL TKLENGSLKL NLEAELIEEV IAEALDHADP NLANYKVNVS IDSDFLMLLM
DTQLIVQVIV NIVNNAVHYT PAGSSISISV KNEGRTARIE IADNGPGIPK KDKERIFDMF
YTSDSNSADG RRGMGLGLFL CKSILEAHGS SIYINNNYPN GTIIGFTLEV LEVSTHE
//
