ID   A0A016RTC4_9BILA        Unreviewed;       257 AA.
AC   A0A016RTC4;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   RecName: Full=Clc-like protein {ECO:0008006|Google:ProtNLM};
GN   Name=Acey_s0379.g319 {ECO:0000313|EMBL:EYB81558.1};
GN   ORFNames=Y032_0379g319 {ECO:0000313|EMBL:EYB81558.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB81558.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYB81558.1}.
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DR   EMBL; JARK01001715; EYB81558.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016RTC4; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   Gene3D; 1.20.140.150; -; 1.
DR   InterPro; IPR009545; Claudin-like.
DR   PANTHER; PTHR37446; CLAUDIN-LIKE IN CAENORHABDITIS; 1.
DR   PANTHER; PTHR37446:SF1; CLAUDIN-LIKE IN CAENORHABDITIS; 1.
DR   Pfam; PF06653; Claudin_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        9..27
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        90..114
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..146
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        229..251
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   257 AA;  28108 MW;  BA17882FE277CD52 CRC64;
     MCFSMCAQVI YGIVMFACLV LTLGAMFTSN WRLITETIEG SIRNRTLPGH MGLFPFGCQM
     PGEDTNGTHG GFNLKYCEEW WLNLQTWEKI VSAAMVVAAL AEAFALVWNC FTWCACCCKQ
     FLIHPLTLAS LLATIALGTA VAFYGINNQS AFESLPILID YGRLLSNTIK GNRSTISGIS
     GLNSTISTAA KIQKSRTWDL LEDKVNVSEG VNNWNDIKDK FETEVGYSFW LACGALVLAL
     ADTVVAVFAT CMGKACL
//