ID A0A016RWT1_9BILA Unreviewed; 341 AA.
AC A0A016RWT1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 38.
DE RecName: Full=K+ channel tetramerisation domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0351.g3231 {ECO:0000313|EMBL:EYB82766.1};
GN Synonyms=Acey-C32C4.1 {ECO:0000313|EMBL:EYB82766.1};
GN ORFNames=Y032_0351g3231 {ECO:0000313|EMBL:EYB82766.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB82766.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB82766.1}.
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DR EMBL; JARK01001687; EYB82766.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016RWT1; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0008076; C:voltage-gated potassium channel complex; IEA:InterPro.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR CDD; cd18317; BTB_POZ_Kv; 1.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003971; K_chnl_volt-dep_Kv9.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR InterPro; IPR003131; T1-type_BTB.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR11537:SF121; BTB DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11537; VOLTAGE-GATED POTASSIUM CHANNEL; 1.
DR Pfam; PF02214; BTB_2; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01494; KV9CHANNEL.
DR SUPFAM; SSF54695; POZ domain; 1.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Potassium {ECO:0000256|ARBA:ARBA00022958};
KW Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 198..220
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 274..294
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 315..336
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 51..148
FT /note="Potassium channel tetramerisation-type BTB"
FT /evidence="ECO:0000259|Pfam:PF02214"
FT DOMAIN 202..327
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT REGION 15..39
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 341 AA; 39569 MW; 4029181F47CE3756 CRC64;
MNVFIQRHPG ADAVTKMKNA SRHSRSLRDR HRQEGTEKDD ATVADATDLY LRLNIGGKSY
CIRKELYTEE RTLMHDIVEA THEQRLAIVD GCDPITGEYY IERNSRIADH IIDFFATGSL
HKPQNMCIEK FKEELAYWRI SHDHLSTCCA FPREASLLKP HLQQSTTFDE YETDFDGAYL
YSFRLSTWRF LEDPQSSVPA AIFAILSVLF VFASVFGLIL GSMPEFQEDP TNASAYHTMH
AKTSELEKLN KFRPAHTRNE EFPDFVYRPT DNPAFVLVVL EYVCIGWFTF EYFIRLIIYP
KRGEFIRKTL NVIDMLTILP FYLELCLPLV GIQSHFKEFT G
//
