ID A0A016S7B4_9BILA Unreviewed; 544 AA.
AC A0A016S7B4;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE RecName: Full=Major sperm protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0277.g1106 {ECO:0000313|EMBL:EYB86513.1};
GN Synonyms=Acey-hpo-28 {ECO:0000313|EMBL:EYB86513.1};
GN ORFNames=Y032_0277g1106 {ECO:0000313|EMBL:EYB86513.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB86513.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB86513.1}.
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DR EMBL; JARK01001613; EYB86513.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016S7B4; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00170; SEC14; 1.
DR Gene3D; 3.40.525.10; CRAL-TRIO lipid binding domain; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR001251; CRAL-TRIO_dom.
DR InterPro; IPR036865; CRAL-TRIO_dom_sf.
DR InterPro; IPR036273; CRAL/TRIO_N_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR46384; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR PANTHER; PTHR46384:SF1; MOTILE SPERM DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF00650; CRAL_TRIO; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SMART; SM00516; SEC14; 1.
DR SUPFAM; SSF52087; CRAL/TRIO domain; 1.
DR SUPFAM; SSF46938; CRAL/TRIO N-terminal domain; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50191; CRAL_TRIO; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 472..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 118..219
FT /note="CRAL-TRIO"
FT /evidence="ECO:0000259|PROSITE:PS50191"
FT DOMAIN 318..435
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT REGION 231..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 433..452
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 516..544
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..251
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..451
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 544 AA; 62410 MW; 59F01835842B37AC CRC64;
MQDLRARILQ DKLSRKCSEE DLKRLKSEDW WLSTFLRAHN YDVDVTYAVI AECVQWRKNF
QVENISILGI KPLLDRQVVY LHGKDLADFS ILWINLAQYR PGDTGFENVF VFWLERHTME
TKGQPLTILL DMTSTSMKNM DFNIFKFMLH ALKYYYPSIV QDMIVFESPT MLNASWRVVK
SWLDPAHPQI HQVTRQSISQ FVDSKYLPAH MGGEDTFKFT MDDLAKCLPA AGRQENGNNN
SDAEQSQEKN VLDSVVMKGA VTFDDDDEDA TRKAPLTLNA RKMSNGNGSV KRSIPQTLKP
AVDARLNSPE VDWIKNAFLY ISPRDVLTLH RVENLAEYLE VVAIRNTSTE SVMFKIKTTS
PEKFRVRPSM GVIPAGSTEI IRVYLQSEYK TSCSREKFLL MALETENNNL ETFTDLWKKV
DKDKKVEQKL RCRVSDDGSN DGSDKPERKI SASTQHGLID ELRTECGRLQ RVHYMLVMVV
LVLFLTQAAL LIYARSNYST LRASIEELAL KISATQCPEP TTEPTPSPIT PKYERPPDMY
EEDL
//
