ID A0A016S7P0_9BILA Unreviewed; 242 AA.
AC A0A016S7P0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Thiamin pyrophosphokinase catalytic domain-containing protein {ECO:0000259|Pfam:PF04263};
GN Name=Acey_s0275.g1070 {ECO:0000313|EMBL:EYB86685.1};
GN ORFNames=Y032_0275g1070 {ECO:0000313|EMBL:EYB86685.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB86685.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB86685.1}.
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DR EMBL; JARK01001611; EYB86685.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016S7P0; -.
DR STRING; 53326.A0A016S7P0; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR GO; GO:0004788; F:thiamine diphosphokinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR GO; GO:0009229; P:thiamine diphosphate biosynthetic process; IEA:InterPro.
DR Gene3D; 3.40.50.10240; Thiamin pyrophosphokinase, catalytic domain; 1.
DR InterPro; IPR007371; TPK_catalytic.
DR InterPro; IPR036759; TPK_catalytic_sf.
DR PANTHER; PTHR13622; THIAMIN PYROPHOSPHOKINASE; 1.
DR PANTHER; PTHR13622:SF8; THIAMIN PYROPHOSPHOKINASE 1; 1.
DR Pfam; PF04263; TPK_catalytic; 1.
DR SUPFAM; SSF63999; Thiamin pyrophosphokinase, catalytic domain; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 34..108
FT /note="Thiamin pyrophosphokinase catalytic"
FT /evidence="ECO:0000259|Pfam:PF04263"
SQ SEQUENCE 242 AA; 26720 MW; 2A6D8D9FE896D5F3 CRC64;
MVRHLSPLDC LLKPASNVCI WLNGAVEAER PSWARLWNVA QKRYSTDGGA NRIVGREPEL
APPDVVLGDM DSILSIVAEG LKSRCLLVHA PDQDKTDLTK CLEYIAQDFK KGLQLGFLFH
ISSFKHVGVG ALARKLLALY GRSDSFAVKM CHVPNVGPTT LLENVHENQL FNPKAFLSSI
SVSLGKVTQA LVGFDPSTKR FSPAHCCGRS DVLLVPNVLC SSPRVLTHFW WFAIGERQRA
KM
//
