ID A0A016S8Z7_9BILA Unreviewed; 551 AA.
AC A0A016S8Z7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=FYVE-type domain-containing protein {ECO:0000259|PROSITE:PS50178};
GN Name=Acey_s0271.g898 {ECO:0000313|EMBL:EYB86926.1};
GN Synonyms=Acey-rabs-5 {ECO:0000313|EMBL:EYB86926.1};
GN ORFNames=Y032_0271g898 {ECO:0000313|EMBL:EYB86926.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB86926.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB86926.1}.
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DR EMBL; JARK01001607; EYB86926.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016S8Z7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 4.10.860.20; Rabenosyn, Rab binding domain; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR021565; Rbsn_Rab-bd.
DR InterPro; IPR036531; Rbsn_Rab-bd_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13510; FYVE-FINGER-CONTAINING RAB5 EFFECTOR PROTEIN RABENOSYN-5-RELATED; 1.
DR PANTHER; PTHR13510:SF44; RABENOSYN-5; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF11464; Rbsn; 1.
DR SMART; SM00064; FYVE; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF140125; Rabenosyn-5 Rab-binding domain-like; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 175..209
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT REGION 462..492
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 551 AA; 61995 MW; 801124F4F95FC331 CRC64;
MADTVRQGFI CPFCMTDLGD FPRLQSHVDT VHPERGQDLT ETVIDNVKGF FDKAKRGMRI
LDAKMSAELS QVNIGVSNSV ADLASMASAV HERVNEKARV ARPAAVIRPP PVRAEIGVTR
SNTEYFRKVR DSSINESAVR TNMLIIRLDR LINECPVDPT KRKEFEREVV PWSADSESLH
CTQCAAKFGL ARRRHHCRLC GRVMCHQCSK FLSFLSARKL TNPALAAEML SSDVPSTTAE
VSPSHRRRLL EMTQKTTGKV ISFIEGAVSK MQTTDGSEVS LGSLLQQDAN ECLRVCGSCM
ADLSRREQMM EQRNPPILAE QYETLDRMIA EASAMVPSYS RMADSINNGE TMYTLAAAEQ
LRCRLLQKQR DIDSLSQSIV AEAENERCGV KEAQLRKNIR FACLQTLQGM VSSMVSLPTE
QQYEKLVETH KREVARQIEE SRMRATNENV GVRACASLPS VVSRDRPTIS TSPDRPRKQT
EDGWTPQQTK TYNPFMEEED RLHPMFEQRD IIKGYLAQAA TAGRLEEVEM LERNLRDLEG
EMLKMGLISP T
//
