ID A0A016SB03_9BILA Unreviewed; 690 AA.
AC A0A016SB03;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Immunoglobulin I-set domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0256.g374 {ECO:0000313|EMBL:EYB87863.1};
GN ORFNames=Y032_0256g374 {ECO:0000313|EMBL:EYB87863.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB87863.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB87863.1}.
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DR EMBL; JARK01001592; EYB87863.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SB03; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR CDD; cd00063; FN3; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR45842:SF12; KEKKON 5, ISOFORM A; 1.
DR PANTHER; PTHR45842; SYNAPTIC ADHESION-LIKE MOLECULE SALM; 1.
DR Pfam; PF00041; fn3; 1.
DR Pfam; PF07679; I-set; 4.
DR SMART; SM00060; FN3; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR SUPFAM; SSF48726; Immunoglobulin; 4.
DR PROSITE; PS50853; FN3; 1.
DR PROSITE; PS50835; IG_LIKE; 4.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 30..122
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 144..235
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 272..368
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 407..498
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 501..590
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..32
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 690 AA; 77484 MW; 75ED69A3DB248B82 CRC64;
MLSCYISSGS DRSLTSRPRD EPTEPEESKP RIRRGLYNQS IHQGSVVDMI VCATGWPTPT
VKWFKDGEEL TSDGPTGRRV IFTDDLGIHH LVILNLSPED EGDYSLVATN KLGEARTEGA
LSVIRPRQVE GYGPEDKGGM PFPPGFVRQL KNKHVFSRMP TIFDCLVVGH PAPEVEWLHN
GKRVTPGGRI KIQSCGGGSH ALIILGTRVE DAGEYVAVAR NIHGTASSSA ILDVTVPHLD
TIKFDGGIDV TPYLTEEYGF KKLNYASLPT PPDRGPFIKE VTGHYLTLSW IPTKRAPPRY
PQVSYVIEIR ELPEKEWTLL DYNIPEPVCK VRNLELGKSY QFRVRAENIY GISDPSPASP
PSRLMAPPQP VLDKKTKKVI PLLDPYAEKA LDLAHAEQYA CAPWFAPGVV DKRYCAENDV
LTITLNVAGY PDPEIKWKFR GWDIDTTSPM SKCKVFTIGG TETTLMISAF SKDNVGQYQC
FATNPYGEAQ QNIMVDLAIR PNFIQPLYNR TFSDAQPMRL DVRVEGQPFP ELKWLKEWRP
IVESTRVKFV QEGPYLCSLI VTDPMWRDSG IYTCIAVNDA GQATTSCSIT VEADGDFNDV
ELRKKRVVVE ARKIREIYEI AEEDETLAAS GAPFRVRERR TAHEFLAQLK PLNDALQRDV
DMYNSVDHEN IVRFHEVIKD DNLALVVYEE
//
