ID A0A016SBD0_9BILA Unreviewed; 637 AA.
AC A0A016SBD0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=Acey_s0254.g284 {ECO:0000313|EMBL:EYB87950.1};
GN Synonyms=Acey-syg-1 {ECO:0000313|EMBL:EYB87950.1};
GN ORFNames=Y032_0254g284 {ECO:0000313|EMBL:EYB87950.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB87950.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB87950.1}.
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DR EMBL; JARK01001590; EYB87950.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SBD0; -.
DR STRING; 53326.A0A016SBD0; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR11640:SF153; IRREGULAR CHIASM C-ROUGHEST PROTEIN-RELATED; 1.
DR PANTHER; PTHR11640; NEPHRIN; 1.
DR Pfam; PF08205; C2-set_2; 1.
DR Pfam; PF13895; Ig_2; 1.
DR Pfam; PF13927; Ig_3; 2.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 4.
DR SMART; SM00408; IGc2; 4.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..637
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001489260"
FT TRANSMEM 590..611
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 18..110
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 124..247
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 254..339
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 342..418
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 481..573
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 637 AA; 70418 MW; 65C4AF9008086A02 CRC64;
MFSFLLVLCL VVFVEGEQTI VEGPQESFVF LGQTVVLRCK VSNQKGAVQW MKNGFGLGVD
RQLKFFPRYS MIGSASRGEY NLQITNTTVG DDDIYACQIN EAASEPSVIS NPAKLTVLIR
PTPPKLQKTS HFMNAVAGEA VTQSCLSRKG KPPPRLGWAL SNDAEGRNIS TWLGETRVKF
SHLFKTSGVT QESLQAEVEE EIQKDGYGYI VSSNISFVPR PDDDRKYILC LSQHDTFPGK
SESDSLKLIL QYAPRVNLTL ASQQQLREGG SALLACNVDA KPLDNIRISW YKNGNQLLPH
TTDTFFLETL KMEDHRTEYT CQASNSIGTS HASLRIDVSF GPRIMSTPQE KEVSEGESVS
FRCDAVGNPT PTVLWTRAGD DQIVAKGDTI TISNARNWQQ GEYICTAIVD GFKHASVSHF
LHIRGEIKNY LVFLATITKC VCKIHSRPVL IRAQNEAVLN VACKGSARTQ AAIWKRDIYG
PPLITVPAEL SANLGESIEM SCHISGRPKP LEVHWKRNGE ELDYASGKMQ VHQIPRSYGV
ESRLIIRDLR EIDMGVYNCT ANNGIGHDAR TVTLKARGVT DVFASLGTTA LVALSAGILA
LLMLICCCLI CRRHSLPEKG ARFLGQQLFR YIIRGSP
//
