ID   A0A016SGD0_9BILA        Unreviewed;      1436 AA.
AC   A0A016SGD0;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=Fanconi anemia group D2 protein {ECO:0008006|Google:ProtNLM};
GN   Name=Acey_s0232.g3035 {ECO:0000313|EMBL:EYB89406.1};
GN   Synonyms=Acey-fcd-2 {ECO:0000313|EMBL:EYB89406.1};
GN   ORFNames=Y032_0232g3035 {ECO:0000313|EMBL:EYB89406.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB89406.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYB89406.1}.
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DR   EMBL; JARK01001568; EYB89406.1; -; Genomic_DNA.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR029448; FANCD2.
DR   PANTHER; PTHR32086; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   PANTHER; PTHR32086:SF0; FANCONI ANEMIA GROUP D2 PROTEIN; 1.
DR   Pfam; PF14631; FancD2; 2.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   REGION          1..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          858..888
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1403..1436
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..44
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1403..1418
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1436 AA;  161848 MW;  928DA50238F41213 CRC64;
     MWSDAEDDLF DDFADPGAAA GDAQGDVGSS FSSQKSQPSQ RSFAGKDLRA NEFQDTQRRD
     RVVVNYNNDT GEAVEPSNEF EKMLLRDGIE VRSDENYKKY MYIGDTTSDL LVAKLDKNMN
     VRRYRDDLLS AFEEALQQRN NFVTYLEPSH STCGVQEAIF RVLILCRSSQ AKAFDLLMNQ
     LQNLQKEGQS SLNLSHLCIA QIRFINRIYD SRPLFCSIFE REIEHWIPEI RNSLISSIPE
     VLTDVSVQLE AVQELQSLLL RDVKTDPTGC KLAVIAALSL LNSDAETTKK LQTRVVQSLS
     SFDVELLPSL IELLLRRLDN SSKNAFADLL CQFSSNLQIE KLRLSRRGKP RRTLDDIVGE
     VFDKLSQFVV LGGDTRWKEV NRFLRAMGPS EKGALDVASQ ESVIAPEADT PHTLGLFDVM
     LSITLLSLRT CPLNVATSIK QRFVQSQDNI ECMYRLFSDA LKFKQFCERN VNPIISVAQQ
     CLWSAKPEAQ KLGAKLFKEL VLALPKRREV ILKTMLSHAV QSETESEAVL SEFTALIDES
     PEAVEPYVGL VSEYFFILDR MTIDNVKRFF RAVFRLYAAK PSTVSQKDNL NVMIPLLLRS
     ADNVQPVFGV LAALMKLETA LLLEESSTRE VDVQNSLKFL DEARTSASYV RICCFSGLAE
     VLRVCFGTKK CTAMHEWLTV FVEEFRSDFF TDCYEASSEL ESERYVYQDS NLWLKCSDSQ
     NLGEAIPLLE AVMEAIRLQE TWPTADTMEA TQRDRWSRIF YALSANISVQ GVDDNSKSSC
     DTLFRTIQWI RTLFNVFSEE QTCPGVDSAT LDELWTKKFL LMFECQKELA FRAKFLGQWL
     IPDQTPLAPI TVIASEAKKK PPKKAPKRKR NAPAEEAEPA EDVLPSTQPP VISDCEKKRF
     VGKSVPLAKL ASCMKTLKLS AVVKLMELTQ GRRRASILLI DHLQNILKQV CPRIGKKSLP
     WAKGVASAAS IHGDIGRILA EVDKMLPLLW NTFSKTVSYF RDQLNSSAVV TTETDVSDQL
     ADLLRLCLGI LEHLFSWNHV TPLPSDPDAV ATRKKSRRDK LMEALEHAIL QEDSERSAGS
     EAEKSVYEFL IDTCEVVPNV NVAVALLDCA ATIRSSREEL SNKLARHTLG FLKKEWVDKE
     GKPIKGASLT SAVKKLLSHY LNLRPVNYRL CAIQWILAKK LADLVPHDER RKSKVYDQES
     DDPDLNERDT KQIFACFTRA TFGTIYKVLF VAMNDALASE VVLPSGNVLR RRVVQECLRT
     WNIAAGCVSL FGLMLRVREL RNTSLLVAAI KEGRRFLAMM CNKNSSFMYL LEDKSRLASV
     TEHVVEIIKS VQIGNRNFQN ICVHAKANRS NILLKLVPDF RVTNEQWMRA IQAKLTGINC
     QDAFEIGLLK PRDINGEEIV YSADDRSSST CSESEAEQAG EEAQSDSDDG NASEVY
//