ID A0A016SNB7_9BILA Unreviewed; 1189 AA.
AC A0A016SNB7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN Name=Acey_s0198.g1618 {ECO:0000313|EMBL:EYB92070.1};
GN ORFNames=Y032_0198g1618 {ECO:0000313|EMBL:EYB92070.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB92070.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB92070.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; JARK01001534; EYB92070.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016SNB7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR InterPro; IPR002656; Acyl_transf_3_dom.
DR InterPro; IPR003392; Ptc/Disp.
DR InterPro; IPR043968; SGNH.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR23028; ACETYLTRANSFERASE; 1.
DR PANTHER; PTHR23028:SF115; ACYL_TRANSF_3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01757; Acyl_transf_3; 1.
DR Pfam; PF02460; Patched; 1.
DR Pfam; PF19040; SGNH; 1.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 1.
DR PROSITE; PS50156; SSD; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..39
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..265
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 277..304
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 310..331
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 351..371
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 377..398
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 446..466
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 609..628
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 720..736
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 748..767
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 779..799
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 806..827
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 246..404
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 1189 AA; 135426 MW; E6A59135A9EC890D CRC64;
MLLSSRFGQL GTTVGARPLT FFLSSVALFV ISVLLLIAVP PEVHLNFDEG YTTPHAPSIR
ELHTQMQFFG TKGKPWYMAL FAEPRDQENG SMIESTEFDE FKSFYKRIKS NVVIRQEGNR
TITYMDYCGK TCDVNDPIFK THALSFFGLQ WPETSIFMYK SNVGKYFFLR EMRGNEIVKS
RLTALYFIAF LNNTQAMEDL RHFEAIVSDH VAKHNADKTK VTTITQHSAR GMQMEIARGM
KFVFGKLIGG VFLAGIVMLL CFLVLNRIHE RCNGRVLLLS FGATFLPIMA LITAASFCSF
IGIHTNTLTI IAPALAFAIG IDGMLILYNA WISHHKTSNV KDHMTEVFSS CFPSITIASS
VALGLIFGGM YPTEEFAIFS FYLGLSVVFV YAYLIFYFPA LMVWCSSIET HLPLPQHCAK
SPKVVKQRPW YEAFLGQYAE CLSHSAWLKI FAVSLFCLCL ALPTYMGSSK IHANIDYRHL
LPPDSPNNKG VHFMSDVVWF EFFNVLYFIE KPPRFDDPQS YQRFKHLTHT IFGIVQHQSA
PEAQHAPVRS MLVHFECVRV RTRAARALSA SRLDQAGDLF THTWSLCVEM QFYLLVPTVF
LFYQIDHILF RWLYLSTVIA TSFCYYMVSG SNVSFNSVFS RIWQFGVGIS AYVISESESY
IKEEVEHQIL EESGESESMH RVPISFKWGM KCIRSETLFH CLLIAMGALT LSPFIFHSHF
LRISITLGMG IILALGSAHQ CGMLNQRWLV YLGDISYALY LVHWPVYVWT KFHYDRSSGA
VFFVACSCVV VAALISSTFE RYYLSLSYPG VLFLVTSMYA AIAFIMYNQE QISLFLEKQI
VGSPPTSELS KQIPTNLTIE EAIRMNAMFD RNEYKNLVPP RCHPNNTEHG FCVFESQGLK
GSLNMMIVGN SYAPNVAEII YDSFAGLAKN ISKYSRSRCE VLVIGGDNCR KSYLSYKKYV
EEVRPDVLFI ICRAFEMDTP ILGTVTMDPL FLEAKATLEK YNTLVRTKIF VLDSTPGVDA
DHIKKLNAWI RNGNITGVYT YVLLMGTQLY KFSMKLHRKN SANRVRRVIP RCEMKLIRFI
VTSLIVRLTP NDPASFKLAS LELLYIYSPL LSAGVPLTQQ WTRPSTFLYY WAPAHRFRSS
GPSPVISPTL VRAQPDNPRG VAIDPYLYYF GYHPHRQFIL LRVLLILES
//
