ID A0A016T529_9BILA Unreviewed; 356 AA.
AC A0A016T529;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE RecName: Full=SAM domain-containing protein {ECO:0000259|SMART:SM00454};
GN Name=Acey_s0137.g2028 {ECO:0000313|EMBL:EYB97797.1};
GN Synonyms=Acey-ZC190.4 {ECO:0000313|EMBL:EYB97797.1};
GN ORFNames=Y032_0137g2028 {ECO:0000313|EMBL:EYB97797.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB97797.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the SMAUG family.
CC {ECO:0000256|ARBA:ARBA00008232}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB97797.1}.
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DR EMBL; JARK01001473; EYB97797.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016T529; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0030371; F:translation repressor activity; IEA:InterPro.
DR GO; GO:0043488; P:regulation of mRNA stability; IEA:InterPro.
DR CDD; cd09557; SAM_Smaug; 1.
DR Gene3D; 1.25.40.170; Smaug, PHAT domain; 1.
DR Gene3D; 1.10.150.50; Transcription Factor, Ets-1; 1.
DR InterPro; IPR037093; PHAT_dom_sf.
DR InterPro; IPR001660; SAM.
DR InterPro; IPR013761; SAM/pointed_sf.
DR InterPro; IPR037634; Smaug_SAM.
DR PANTHER; PTHR12515:SF5; PROTEIN SMAUG; 1.
DR PANTHER; PTHR12515; STERILE ALPHA MOTIF DOMAIN CONTAINING PROTEIN 4-RELATED; 1.
DR Pfam; PF00536; SAM_1; 1.
DR SMART; SM00454; SAM; 1.
DR SUPFAM; SSF47769; SAM/Pointed domain; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repressor {ECO:0000256|ARBA:ARBA00022491};
KW RNA-binding {ECO:0000256|ARBA:ARBA00022884}.
FT DOMAIN 132..195
FT /note="SAM"
FT /evidence="ECO:0000259|SMART:SM00454"
SQ SEQUENCE 356 AA; 40082 MW; 302E7D0D6A27711E CRC64;
MLHRHTAISA DVFCEGPPER TSVCGERFSV ELRLFQLTRN ETVMQPGSST VACFADLQSS
FSTTLSTPPA PSLPNNSSQC LISADGFYCK PAEQFFSQLE VPAPQQYQQR RLDVAPSTVS
CSPPLTPPAL ELLKPGMRDV PAWLKSLRLH KYTSLFAELS YEEMMTLDEA ELERRNVTKG
ARTKILQSIQ KLYSRSADLR TMHERLSISH PQRCLRCAIA TLRQMIATPM IPYTPSPGES
SDSVDGFVCI SYISDQNVPG LIFNVLRDVQ QAVFISGRQP LDLEYEYLLM LFTVFDRLCN
NEAFTAAQKQ RVHQWKRLAR KAIRPADVRR QRIGLPHSGK CELCHYKVSS SGPFTS
//
