ID   A0A016T5F4_9BILA        Unreviewed;       600 AA.
AC   A0A016T5F4;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Carboxylesterase type B domain-containing protein {ECO:0000259|Pfam:PF00135};
GN   Name=Acey_s0135.g1884 {ECO:0000313|EMBL:EYB97912.1};
GN   ORFNames=Y032_0135g1884 {ECO:0000313|EMBL:EYB97912.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB97912.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYB97912.1}.
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DR   EMBL; JARK01001471; EYB97912.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016T5F4; -.
DR   ESTHER; 9bila-a0a016t5c5; Carb_B_Nematoda.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR002018; CarbesteraseB.
DR   PANTHER; PTHR44590; CARBOXYLIC ESTER HYDROLASE-RELATED; 1.
DR   PANTHER; PTHR44590:SF3; COESTERASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00135; COesterase; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          50..568
FT                   /note="Carboxylesterase type B"
FT                   /evidence="ECO:0000259|Pfam:PF00135"
FT   REGION          86..107
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        87..101
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   600 AA;  67794 MW;  375365E7DBE3FF3D CRC64;
     MGVYELDDVG VDELDEMDSD EVSYCNEHFA ETWSTMGISS SSHHQSQGDS RMVKTQYGAV
     IGRRFVFENK QVDAFQGIPF AKPPIGELRF RKPEPPEPWD GVKETKAFGP RGIQKDNTFL
     DKMKHGRTSE DNLYLNVFSP TWNPSTPSGF AVLVFVHGGG FLSDSSVKYG DADICEHLCT
     KDVVVVTVQY RLGHLGFFTT GDDTCRGNFA LWDQTMALRW IQDNITFFNG DPRNVTVMGQ
     SAGGASVDLL SICPPSRDLF HRVIPMAGNA SCRWSTHNNL VEVCRKFAEA NDIHDFLHSE
     KMIEKLREVP ASKFAMSLMD TLSDSKADLC PVAPRIDGEF ITKPISELRK EAPGMPMLIG
     CCASEGLIML MGKRSSLGGI MEEISKLVPE DEYPSNFMQL RQEIFWKLIK KEDIEDSDEV
     TRAYVEILGD VFTNIGVQKA VLETVEAHNV PVYFYSFDYF NPKSWGPLGL RMPFKDATHC
     TELAYIFAHG IIWSYDFNEE DKQMLEMTTR MWTNFAKYGD PNGVPTDESS IVPSLHEKPL
     KWEPATTECP QRHLSISLNP QMRDEYKTIV HSGDATDQKG RQHSLTEYLQ IISEYPQIYS
//