ID A0A016T661_9BILA Unreviewed; 491 AA.
AC A0A016T661;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=G-protein coupled receptors family 1 profile domain-containing protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0131.g1641 {ECO:0000313|EMBL:EYB98463.1};
GN ORFNames=Y032_0131g1641 {ECO:0000313|EMBL:EYB98463.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYB98463.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYB98463.1}.
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DR EMBL; JARK01001467; EYB98463.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016T661; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:InterPro.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 1.
DR InterPro; IPR019424; 7TM_GPCR_Srsx.
DR InterPro; IPR047130; 7TM_GPCR_Srsx_nematod.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR PANTHER; PTHR23360:SF37; G_PROTEIN_RECEP_F1_2 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23360; UNCHARACTERIZED; 1.
DR Pfam; PF10320; 7TM_GPCR_Srsx; 1.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..19
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 20..491
FT /note="G-protein coupled receptors family 1 profile domain-
FT containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001487138"
FT TRANSMEM 341..364
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 385..409
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 421..438
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 34..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 114..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 266..285
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 121..146
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 268..285
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 491 AA; 56256 MW; 56A2D25AB30BB131 CRC64;
MQLTTFLPCL AALFTAVHGQ YYPQQASQQY YPQQQYAPQP QYPGQWRQWD QPQSYQSQPQ
FLPQQPVQAN YQQNFAFPPQ QQQQRFPLPQ YQQQVPPPPQ QFVPTLQQFQ QQVPQFAQQQ
YQQRPPPPPP VVFNQPPPPP PPQPVQQAVF KPRPVYREGP KIYEQQFKIN KAVPVEGFMP
QLVEPQLPIQ QRIRVPPPPE RFHPHLADIY GQPSLPDRPS SSTRPTIILI GESLPEGAYG
AEERLIDGNH PSYIEDTAKT TPVDQPQVVI PKPAPRRPSV PRPQPPVRYR ACPTAPYITV
IFVLCSLFAI PTVVWGFVAQ DDEVIPYCNP PLGLAPNVSH FWSVSNVVVN CIVLLVYATI
IGFVHFRAKS RACHEQRKVV RRLQVIVIVF IFSWFMAILG VNVGILLGFP PDIFQLWQSN
MGFFAMICYS QTFYVCIWRS KEYRSAFIEQ LQLMVCRKPQ VKIEVSTSRS QVTRVITVQA
QTKTALRSTC T
//
