ID A0A016TM52_9BILA Unreviewed; 409 AA.
AC A0A016TM52;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=XK-related protein {ECO:0000256|RuleBase:RU910716};
GN Name=Acey_s0093.g2679 {ECO:0000313|EMBL:EYC03593.1};
GN Synonyms=Acey-ced-8 {ECO:0000313|EMBL:EYC03593.1};
GN ORFNames=Y032_0093g2679 {ECO:0000313|EMBL:EYC03593.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC03593.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU910716}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- SIMILARITY: Belongs to the XK family. {ECO:0000256|ARBA:ARBA00008789,
CC ECO:0000256|RuleBase:RU910716}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC03593.1}.
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DR EMBL; JARK01001429; EYC03593.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TM52; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR InterPro; IPR018629; XK-rel.
DR PANTHER; PTHR16024:SF6; CELL DEATH ABNORMALITY PROTEIN 8; 1.
DR PANTHER; PTHR16024; XK-RELATED PROTEIN; 1.
DR Pfam; PF09815; XK-related; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU910716};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|RuleBase:RU910716};
KW Transmembrane helix {ECO:0000256|RuleBase:RU910716}.
FT TRANSMEM 55..80
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 86..112
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 139..157
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 232..253
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 359..378
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
FT TRANSMEM 390..407
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU910716"
SQ SEQUENCE 409 AA; 47533 MW; 59AC13E707275335 CRC64;
MNFYYWLRYD VGMFEKHNAK LIYLTENGYA SDQEDGGVAG EQLDRIPRHL FVRRFDLFCF
CFAMVTYCFD IISDVITAAF HYYDDRAVAC LFILLLSVVP SVVLNAVSFA WICDDNYSKA
KAVKSRGNQP NGEDERESYF NHALLCIFQI GPLWWYYKAL VHGIHFRMES DPIKRRKHFC
RMIEAERDAT LLRFFEGFLE SAPQLIIQGN ILSEYLWWHF NEANSIFELP RWVYVQLISM
ALSLLSVCWS ISIQHRSLRM VRPDKVNMHP HESVLQLIWR FSTVASRFIV IVLSVSSYEF
KVVPPLVLHF LVSMAHIKAL QALNIPSRGL EEGLTLINAA IHTFTPFNMA DGPTRWRYAA
AYTVEAIEAI LFFTFWMRDN SIQFPYKKEA AVLSGVLFVI GTYLSMIHI
//
