ID A0A016TTQ8_9BILA Unreviewed; 439 AA.
AC A0A016TTQ8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE RecName: Full=WW domain protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0078.g1202 {ECO:0000313|EMBL:EYC06121.1};
GN Synonyms=Acey-sav-1 {ECO:0000313|EMBL:EYC06121.1};
GN ORFNames=Y032_0078g1202 {ECO:0000313|EMBL:EYC06121.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC06121.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC06121.1}.
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DR EMBL; JARK01001414; EYC06121.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TTQ8; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0060090; F:molecular adaptor activity; IEA:InterPro.
DR GO; GO:0006915; P:apoptotic process; IEA:InterPro.
DR GO; GO:0035329; P:hippo signaling; IEA:InterPro.
DR GO; GO:0042127; P:regulation of cell population proliferation; IEA:InterPro.
DR CDD; cd21433; SARAH_Sav; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 2.
DR InterPro; IPR011524; SARAH_dom.
DR InterPro; IPR030030; Sav.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR47522:SF2; PROTEIN SALVADOR HOMOLOG 1; 1.
DR PANTHER; PTHR47522; SALVADOR FAMILY WW DOMAIN-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00397; WW; 1.
DR SMART; SM00456; WW; 2.
DR SUPFAM; SSF51045; WW domain; 2.
DR PROSITE; PS50951; SARAH; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 256..289
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 291..324
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 384..431
FT /note="SARAH"
FT /evidence="ECO:0000259|PROSITE:PS50951"
FT REGION 134..154
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 176..198
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 439 AA; 49589 MW; 03F563AE17BA520C CRC64;
MLKLTVQSQR GFVNLWIRFC QESKLLLEFI TGYLLCGGKG LCWMFSRSKK QQLPSYIEGT
QGLYVKRASP PPVPSLSSHT HTLAKKTSSA TVDVSASNNN VTCTNKTSVT VSQPAHVESR
ALKTESVALY TDSSAVRPHS DSALSTASTY SLPPSHGHLA VNHLDAVNER KSPIANLSSQ
SFSDPSKREH LRKPLTSSHS IGNVESFMDQ LSTEHSTPVQ QRFVSLQSLP GQGRQFGSSI
IGDNCLVSGT PQQDDLPLPP NWSISVTSQG YRYYVDHNTC RTHWIHPLAR ENLPPGWNKI
FQPSSGVIYY NEMDGRSQVE HPGLAQPLTQ QINQPIVPIN RTESMMVASR RAESAVEHLN
IIHHEEVPEW LMMYSQADTS LDHLLEWDLF NTMQLEQYEE MMLKLYKQEV IDTVRRYERM
RTVLNKEIVR RTQPHPRNE
//
