ID A0A016TZT6_9BILA Unreviewed; 611 AA.
AC A0A016TZT6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=Sodium:neurotransmitter symporter family protein {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0065.g3601 {ECO:0000313|EMBL:EYC08534.1};
GN ORFNames=Y032_0065g3601 {ECO:0000313|EMBL:EYC08534.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC08534.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC08534.1}.
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DR EMBL; JARK01001401; EYC08534.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016TZT6; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015293; F:symporter activity; IEA:UniProtKB-KW.
DR InterPro; IPR000175; Na/ntran_symport.
DR InterPro; IPR037272; SNS_sf.
DR PANTHER; PTHR11616:SF317; PROTEIN CBG07071; 1.
DR PANTHER; PTHR11616; SODIUM/CHLORIDE DEPENDENT TRANSPORTER; 1.
DR Pfam; PF00209; SNF; 1.
DR SUPFAM; SSF161070; SNF-like; 1.
DR PROSITE; PS50267; NA_NEUROTRAN_SYMP_3; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Symport {ECO:0000256|ARBA:ARBA00022847};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 29..52
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 179..202
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 214..238
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 269..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 301..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 365..388
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 400..422
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 434..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 485..506
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 535..558
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 611 AA; 68629 MW; A321DB15A382558B CRC64;
MFGYDDSYGY STALLAVAPY ATQLAMGPVA WLLFFPLFAL PAVSLMLSIG SLSTHGPVLT
YKRLAPIAAG IGWALTWHVS ERLYVEGLRA AQNLLYLVFS LRFNLDWAVE CGHQYNSRFC
VNFDEQNVTV PSEYHHSPEN HWPAQEFNSY VIRGNEPITS IPAVWEPNEW LLGNSKSQFF
FTFPSLPLMV AHALIWTTIY FVLIKCSSNL GTVLSRLCVI VPCALYIFLI VGMSISGFRF
GVKNEMEKEI NQKERDGDPF DYWADIRGFY RTSILTVDYS GAFSGLLLFA TSRLRPGAKS
LNALLLVPLM MLVPMLLSIL RNGCEGHVAE QQPAYTIYAS TDETISFDLL PVCFATSKAG
SLWAIIYYVA QFLYTSLGPM IVYVSFIYQS FVDDVPTVQN FAPIFFALIV TFFAVPSVLL
YMPLGTKITT LFRYTSQSSI VQILCYIIIY FVYGWQTIES DIITTANEPS SVSLLVYLTR
PTSPLYTVLM FTLVPALLCT KFTAVFDLLL RGNDVLQHID AGTCFIPGPI WMRRIVGYGI
MFAPTLIVTV FASYTMYVMM VRHKLPFRDL LKPTSDWMAH TAVNTVGVKE PEILLLTVKE
KGMDSCISQA N
//
