ID A0A016U8T6_9BILA Unreviewed; 597 AA.
AC A0A016U8T6;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Nucleolar protein 10 {ECO:0000256|ARBA:ARBA00015517};
GN Name=Acey_s0051.g2164 {ECO:0000313|EMBL:EYC11356.1};
GN Synonyms=Acey-nol-10 {ECO:0000313|EMBL:EYC11356.1};
GN ORFNames=Y032_0051g2164 {ECO:0000313|EMBL:EYC11356.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC11356.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus
CC {ECO:0000256|ARBA:ARBA00004604}.
CC -!- SIMILARITY: Belongs to the WD repeat NOL10/ENP2 family.
CC {ECO:0000256|ARBA:ARBA00005264}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC11356.1}.
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DR EMBL; JARK01001387; EYC11356.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016U8T6; -.
DR STRING; 53326.A0A016U8T6; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR040382; NOL10/Enp2.
DR InterPro; IPR012580; NUC153.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR14927:SF0; NUCLEOLAR PROTEIN 10; 1.
DR PANTHER; PTHR14927; UNCHARACTERIZED; 1.
DR Pfam; PF08159; NUC153; 1.
DR SMART; SM00320; WD40; 3.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 42..83
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT DOMAIN 362..385
FT /note="NUC153"
FT /evidence="ECO:0000259|Pfam:PF08159"
FT REGION 388..479
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 388..403
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 446..479
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 597 AA; 68303 MW; CF0570E8BAE52945 CRC64;
MRMPRYGRDM AFSLERSDLY LVGASSEVYR LNLELGEWLS PLQTNSTALN CCQFADAHQL
FVCGTTDGQV EAWDHRDKSR VGVLDCVYSL NGSNRNVEIT ALSFRDALRL GVGTSSGQVL
VYDIRSSKPL IVKDHINELP IKKIDFVPRE SENLILSMDS RVLKMWSEND GKPFAAIETE
NGLNDFCRYP NSGLIFFANE APRMQQFFIP ALGPAPKWCS YLEAITEELE ENQSAAVYDD
YKFVTKEELD SLSLSHLIGS SVLRAYMHGY FVDRRLYEKA QLITQPFAYE KYKDRKIRDL
LHEERENKLI KIKVESSQAK VNKELAARLQ EEAATQVQAA SSAKKKKNDK KKAMSAAAIL
EDDRFKRLFN DEDFEVDQDS EQFKRSVLAQ QKEKSAKAMD YAEDDDHVDE EQDMPQSELP
IMDEAEDTLD RSGDDSSSGT NSDTDEEMLP SKKKLEREKA RRKQEQKERH YQQYEEKMKE
REAERAARLV NKPKKFVFHE LDSAESTRKF LDEHVKESND LEEYSSLAAK KSLMQEQGEF
EKHEDVFGGR SMTFTLAKKG AQGREARAAE ERVNSELSAC AYGALAFHVP EKTRKGT
//
