ID A0A016U9P0_9BILA Unreviewed; 300 AA.
AC A0A016U9P0;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=Glycoside hydrolase family 38 N-terminal domain-containing protein {ECO:0000259|Pfam:PF01074};
GN Name=Acey_s0050.g1963 {ECO:0000313|EMBL:EYC11537.1};
GN ORFNames=Y032_0050g1963 {ECO:0000313|EMBL:EYC11537.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC11537.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC11537.1}.
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DR EMBL; JARK01001386; EYC11537.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016U9P0; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0004559; F:alpha-mannosidase activity; IEA:InterPro.
DR GO; GO:0006013; P:mannose metabolic process; IEA:InterPro.
DR Gene3D; 3.20.110.10; Glycoside hydrolase 38, N terminal domain; 1.
DR InterPro; IPR011330; Glyco_hydro/deAcase_b/a-brl.
DR InterPro; IPR000602; Glyco_hydro_38_N.
DR InterPro; IPR027291; Glyco_hydro_38_N_sf.
DR PANTHER; PTHR11607; ALPHA-MANNOSIDASE; 1.
DR PANTHER; PTHR11607:SF69; ALPHA-MANNOSIDASE; 1.
DR Pfam; PF01074; Glyco_hydro_38N; 1.
DR SUPFAM; SSF88713; Glycoside hydrolase/deacetylase; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..31
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 132..258
FT /note="Glycoside hydrolase family 38 N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01074"
SQ SEQUENCE 300 AA; 33956 MW; 6A9A32684CDC684D CRC64;
MFHRYGRRKG QLILALVLTL STTAFFIYTI GIQKNTTSWS EKAVKANVQQ EIAVPLSKGT
CRSAPDSNTA AEFDMFNVYR DLPESVKTEK SESRRRPSAE KLKVFVLPFT HVDPGIDMDR
KLPGCSVLLL PTGWLKTFDS YSEDTDSILD NMHRFMVSHR NMTFMWAELI FFEKWWAKQN
SSVRNDVRRL VESGRLEIAS GSWVMTDEAN VYYPVTVDNI IEGHQFLEQE FGVSPTVVWS
NDPFGYSNSI QYLFTQAGPA DGGVRKAPGH ESTEGGWVHA DPAVRMTSGY WSADAEVRES
//
