ID A0A016UD05_9BILA Unreviewed; 473 AA.
AC A0A016UD05;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=PHD-finger {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0044.g1034 {ECO:0000313|EMBL:EYC13204.1};
GN Synonyms=Acey-dpff-1 {ECO:0000313|EMBL:EYC13204.1};
GN ORFNames=Y032_0044g1034 {ECO:0000313|EMBL:EYC13204.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC13204.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the requiem/DPF family.
CC {ECO:0000256|ARBA:ARBA00010539}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC13204.1}.
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DR EMBL; JARK01001380; EYC13204.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UD05; -.
DR STRING; 53326.A0A016UD05; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15526; PHD1_MOZ_d4; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR025750; DPF1-3_N.
DR InterPro; IPR013087; Znf_C2H2_type.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45888; HL01030P-RELATED; 1.
DR PANTHER; PTHR45888:SF13; ZINC FINGER PROTEIN UBI-D4; 1.
DR Pfam; PF14051; DPF1-3_N; 1.
DR Pfam; PF00628; PHD; 2.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS50016; ZF_PHD_2; 2.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 1.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 1.
PE 3: Inferred from homology;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 308..336
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 350..410
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 407..457
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 1..68
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 229..287
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..278
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 473 AA; 50808 MW; 3A501E1215008333 CRC64;
MSRTSSCKSA KSSSRSSSSK VRVSSARSSE KVGNVSSSVS LRSSSSRTTA SIDTLSSKSG
GTCSDAARSK SDVSCDRLDA ESGCVLGAVW PPPENMISEG AYIELMKNCS KWNERACNER
KARLRYPFFD QQTGTAHRFN PVFYRLPSQR CNATDAHTIV QYVTQRWRRR QSANSSDAIE
MKMFLRDNPA LDAALNTTAA SAPSGNGWNT SVSDVLDANF DYGQGKGTPK GLFDYNEEGD
DDASNDDGGS DEDDWGSKRK SRKAQGGSSG GGGSSKNKKK ASDSGRAARA SAAAASAAQD
AADEANNYHC TLCSAAYKSL AGLAYHKAFQ HNDPLPTGTS IEISPLLETS SICDLCLGSK
NMNKKTMKPE DLVVCHDCGR SAHPSCLSFN ENVPVIIKRY GWQCIECKSC TICGTSENDD
KLLFCDDCDR GYHTYCFTPK MKSLPENEYS CALCIGTFGA RASAVPKKTG SAN
//
