ID A0A016UFX9_9BILA Unreviewed; 168 AA.
AC A0A016UFX9;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=TIL domain-containing protein {ECO:0000259|Pfam:PF01826};
GN Name=Acey_s0042.g554 {ECO:0000313|EMBL:EYC13826.1};
GN ORFNames=Y032_0042g554 {ECO:0000313|EMBL:EYC13826.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC13826.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC13826.1}.
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DR EMBL; JARK01001378; EYC13826.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UFX9; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:UniProtKB-KW.
DR CDD; cd19941; TIL; 1.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR036084; Ser_inhib-like_sf.
DR InterPro; IPR002919; TIL_dom.
DR PANTHER; PTHR23259; RIDDLE; 1.
DR PANTHER; PTHR23259:SF77; TIL DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01826; TIL; 2.
DR SUPFAM; SSF57567; Serine protease inhibitors; 1.
PE 4: Predicted;
KW Protease inhibitor {ECO:0000256|ARBA:ARBA00022690};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease inhibitor {ECO:0000256|ARBA:ARBA00022900}.
FT DOMAIN 41..90
FT /note="TIL"
FT /evidence="ECO:0000259|Pfam:PF01826"
FT DOMAIN 100..162
FT /note="TIL"
FT /evidence="ECO:0000259|Pfam:PF01826"
SQ SEQUENCE 168 AA; 19027 MW; 1D145E0EC13B1FDD CRC64;
MSFTTYPCEN PHVILVLVAT VFHCVARRRL PPFLLEYKQE CGENEEWTNC GSVCQPSCGK
PSFNVCTSRC FMGCKCKDGF YRDSLGKCIA DCSSERCVFS NEVRKKCGVR SICQPTCLDS
PSDDFLRENC NEAKCVPFEC ECKPGYIRMG GQDEHCIPLA TCEKLRRR
//