ID A0A016UIP7_9BILA Unreviewed; 271 AA.
AC A0A016UIP7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=inositol-polyphosphate 5-phosphatase {ECO:0000256|ARBA:ARBA00012997};
DE EC=3.1.3.56 {ECO:0000256|ARBA:ARBA00012997};
GN Name=Acey_s0039.g147 {ECO:0000313|EMBL:EYC14771.1};
GN ORFNames=Y032_0039g147 {ECO:0000313|EMBL:EYC14771.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC14771.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the inositol 1,4,5-trisphosphate 5-phosphatase
CC type I family. {ECO:0000256|ARBA:ARBA00023599}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC14771.1}.
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DR EMBL; JARK01001375; EYC14771.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016UIP7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0052659; F:inositol-1,3,4,5-tetrakisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0052658; F:inositol-1,4,5-trisphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0004445; F:inositol-polyphosphate 5-phosphatase activity; IEA:UniProtKB-EC.
DR GO; GO:0046856; P:phosphatidylinositol dephosphorylation; IEA:InterPro.
DR Gene3D; 3.60.10.10; Endonuclease/exonuclease/phosphatase; 1.
DR InterPro; IPR036691; Endo/exonu/phosph_ase_sf.
DR InterPro; IPR039737; INPP5A.
DR InterPro; IPR000300; IPPc.
DR PANTHER; PTHR12997:SF2; INOSITOL POLYPHOSPHATE-5-PHOSPHATASE A; 1.
DR PANTHER; PTHR12997; TYPE I INOSITOL-1,4,5-TRISPHOSPHATE 5-PHOSPHATASE; 1.
DR SMART; SM00128; IPPc; 1.
DR SUPFAM; SSF56219; DNase I-like; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 3..241
FT /note="Inositol polyphosphate-related phosphatase"
FT /evidence="ECO:0000259|SMART:SM00128"
SQ SEQUENCE 271 AA; 30983 MW; EDA5729C713BA08E CRC64;
MYPAVQTYLD LDHEAPNFTA LGCVILINAG SIGSVSQFNF TTRSYSPVSK GLNILLNGLE
NSPHIVKRKF PQHFWPTFKW GRKGYMQTRW KVNNRTLDFV NVHLFHDESN LALIHENPFL
YSSNRKRALD YVLEQLMASG NWESSPCFIF GDLNFRLDST SFLNNVVYDI LRSILLSQFD
CFFKAERDDN TAVKINCSQR KTPRKSLVSA PYAIYLGASA EEEIRVCRPH HSREIRRTVA
LSILETAPCR KSRAIASLVA LVRALLEIKS F
//
