ID A0A016UVP3_9BILA Unreviewed; 783 AA.
AC A0A016UVP3;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 39.
DE RecName: Full=PHD-finger {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0025.g1288 {ECO:0000313|EMBL:EYC19280.1};
GN Synonyms=Acey-phf-14 {ECO:0000313|EMBL:EYC19280.1};
GN ORFNames=Y032_0025g1288 {ECO:0000313|EMBL:EYC19280.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC19280.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC19280.1}.
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DR EMBL; JARK01001361; EYC19280.1; -; Genomic_DNA.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15562; PHD2_PHF14; 1.
DR Gene3D; 2.30.30.1150; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 2.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793:SF150; PHD FINGER PROTEIN 14; 1.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR Pfam; PF00628; PHD; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 3.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 2.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 2.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT DOMAIN 209..324
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT DOMAIN 604..657
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT REGION 68..132
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 705..783
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 358..385
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 69..84
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 85..109
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 746..761
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 766..783
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 783 AA; 87552 MW; 1E084BF7F3D52086 CRC64;
MTEAERKSFF NYTTGSLSVD DFIDQIGLHP SLLIDLCLYM VGRILSIGAR GPGKRQIKPT
AAVLDLVLPN AEDEEDDEDF VADNENGSNE GSDSDGSDSD GSEDSSNSSS STDVDDEEND
DVEKDGRNAV SVEGLAGDGK ELPRICALCL NLTQIAKTEE VMQCDKCGLT VHDSCYMSLD
VSEDNESTQS SSSMEPWFCE PCIYGFNEPP YCELCPSRYG AMKRSDVGGR WVHLICALYT
RGVTFGDIDH LTAISWQEMD HRNFGRKSCS GCTNVLEARS GVTTRCELGL CKQYYHATCA
QRLGLLVDHS ESSEHHMGSS QSHRFGDSQA VEPRYINCRQ HSNPDDVQIK KAAAARFLAQ
EERRLMMARK NVLSEREERK RLRARQKYEK QFQSLIGVTI CLPEAFHDKL EKKTRRARHL
TTSPEFFEWF QEKAELSGVE PEQFKKEFTY VSGDSLPLLT PGFSPQFFEY MAHREQVVIA
AEERKLNAIN ASKAAMKKQL DAHMTKLKLN EQSGQLGKER CERRKQLALA FHGALVKLGA
KKIASIVSLL DDAXFDLGAK KIASIVSLLD DASGSNTKRR SSQVIDAPVV SLGTPTKAKK
ERSINVCKEC RKSNDQHLMI GCDSCHEFYH IGCLDPPLEK VPKKVNCEWH CADCCENSEE
EEEHEENGEC SNDGYSTRRL RQRSEIAKAR RLAAAEEENR AYRAAILGST RSSTQKKSPD
KKPTKRASLD IPNRSSPKRQ RPEHANGQKT NGLSSTAHTS YLPEDEELGE DCFVILDDEE
VEL
//
