ID A0A016V0B7_9BILA Unreviewed; 1012 AA.
AC A0A016V0B7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=Phlebovirus glycoprotein G2 fusion domain-containing protein {ECO:0000259|Pfam:PF07245};
GN Name=Acey_s0020.g216 {ECO:0000313|EMBL:EYC21079.1};
GN Synonyms=Acey-R05G6.7 {ECO:0000313|EMBL:EYC21079.1};
GN ORFNames=Y032_0020g216 {ECO:0000313|EMBL:EYC21079.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC21079.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the eukaryotic mitochondrial porin family.
CC {ECO:0000256|ARBA:ARBA00007780}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC21079.1}.
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DR EMBL; JARK01001356; EYC21079.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016V0B7; -.
DR SMR; A0A016V0B7; -.
DR STRING; 53326.A0A016V0B7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-KW.
DR GO; GO:0046930; C:pore complex; IEA:UniProtKB-KW.
DR GO; GO:0015288; F:porin activity; IEA:UniProtKB-KW.
DR GO; GO:0008308; F:voltage-gated monoatomic anion channel activity; IEA:InterPro.
DR CDD; cd07306; Porin3_VDAC; 1.
DR Gene3D; 2.60.40.3770; -; 1.
DR Gene3D; 2.40.160.10; Porin; 1.
DR InterPro; IPR009878; Phlebovirus_G2_fusion.
DR InterPro; IPR023614; Porin_dom_sf.
DR InterPro; IPR001925; Porin_Euk.
DR InterPro; IPR027246; Porin_Euk/Tom40.
DR PANTHER; PTHR11743:SF70; GH26960P-RELATED; 1.
DR PANTHER; PTHR11743; VOLTAGE-DEPENDENT ANION-SELECTIVE CHANNEL; 1.
DR Pfam; PF07245; Phlebovirus_G2; 1.
DR Pfam; PF01459; Porin_3; 1.
DR PRINTS; PR00185; EUKARYTPORIN.
PE 3: Inferred from homology;
KW Ion transport {ECO:0000256|ARBA:ARBA00023114};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Mitochondrion {ECO:0000256|ARBA:ARBA00022787};
KW Mitochondrion outer membrane {ECO:0000256|ARBA:ARBA00022787};
KW Porin {ECO:0000256|ARBA:ARBA00023114};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane beta strand {ECO:0000256|ARBA:ARBA00022452};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Transport {ECO:0000256|ARBA:ARBA00023114}.
FT TRANSMEM 25..49
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 148..173
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 232..533
FT /note="Phlebovirus glycoprotein G2 fusion"
FT /evidence="ECO:0000259|Pfam:PF07245"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1012 AA; 110812 MW; 3195A3429B514204 CRC64;
MSVVERSNKG SRNQKSLERR PQRSGIANVA LGSMQNVILI ALIVVGLVAP TTAKYPICDR
GTVEITEING TYELCFNEEC REFIGNETVR TYELLPSPTH NETRVTVRYG AGDKPIEFTT
ICLNPDICII SSSIFSTSLL GNPHCWPVGA VITTAMILYL ATTMMFLSLY LLITIIRIAS
KRPAQVVQNT CTITGQQVNV QLHSLRPTPL SGGMFITLCV AILVGNGTVA ACQHGFTRHA
TNIVCNQDGN CSYEFSRKLL FNRIQTEHCV EIRHRNKTVG LLKMKLAPTN LVCSKVSKFF
TKSTEIRVFS RVRCPQAGSC FDNVCDKIRP NETIPELTRG SKYPGYSGCQ YTCGGLSCGC
FLPAPSCTFH RVAHVPISDA VYEVVERSEW VPSIHVEVES TLYQETQKED VLLQPYVTYR
FHNFNITATS VQKPALSILN SRFALSENEL LILAVPVECA TRNETLENFR NCINKVVCDC
NTGWTKHHCH CPYNSLRAVA NDSLNHLPLV IPHLEIHTSN GGIIAFTEDV ETVITVQSQL
LVSSTELVYD EKCDIKLTNL SGCYDCLHGA TMGATCTSVN SAKITILCDH NVFAVECGPT
SPKTNVHLRF DSSVAQQKCY TVCGNEKWTL PLNGTLFNHP MKHNSVFKFN EDKYTGTSLL
NLVSEIHMPD LNPLFKVVRL HWKAFTAAGI AALAAAGLTY LFDPVLLIGL VGLCGCSSCA
SSSKSFRCTM SPPTFADLGK SAKDLFNKGY NHGFLKVDST TKAGDSKEVE FKTSASHNLG
SGKLGGNLDV KYKIPAYGLT LTEKWNTENQ LGTIIEVNEQ FGRGLKLTFD SLYAPHAGKR
TGKLKADWSL QTARITAEVG LTSAPVINAA GVFSREGWLF GAAASFDTST NKLASTSLAF
GHQTSNYTLH SFVVNSTDFG ASLFHKVAHN VEIGTILGWK VGGSGADFGL ATKYSPTRDL
VLRAKLNNSS QIAMAATHSL SPDLKMTLST QFNLTSNDHH KFGMGLEYEP SQ
//
