ID A0A016VA95_9BILA Unreviewed; 549 AA.
AC A0A016VA95;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE RecName: Full=Ig-like domain-containing protein {ECO:0000259|PROSITE:PS50835};
GN Name=Acey_s0013.g1965 {ECO:0000313|EMBL:EYC24549.1};
GN ORFNames=Y032_0013g1965 {ECO:0000313|EMBL:EYC24549.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC24549.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC24549.1}.
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DR EMBL; JARK01001349; EYC24549.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VA95; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR Gene3D; 2.60.40.10; Immunoglobulins; 5.
DR InterPro; IPR013162; CD80_C2-set.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR013106; Ig_V-set.
DR PANTHER; PTHR45889; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45889:SF8; IG-LIKE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF08205; C2-set_2; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF07686; V-set; 1.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SUPFAM; SSF48726; Immunoglobulin; 5.
DR PROSITE; PS50835; IG_LIKE; 5.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..549
FT /note="Ig-like domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001493278"
FT DOMAIN 6..120
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 125..224
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 234..322
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 329..434
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 442..531
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
SQ SEQUENCE 549 AA; 60735 MW; 8E6CED4C9DF83024 CRC64;
MILVLPLLLS LITTSKAGFR EKPANQSILL GQDVVFRCAA AKSATSSELY SQWRSNTGSL
LGFHDAGQLA GHQGRYSYLK SSREELHLRI ERVNLEDDGQ FECQMLRPDE GPIRAAAYLN
VIVPPKHVHF ANYQSGAVID VNEEISLNLT CVVPNAKPEA SLTWYINGRK IEEGVQRWSS
YNLNKTVSSF AALQWRPRRS DYRKVLTCEA IHPESQTQIR TNLTLNVLYP PDQPKVSMVG
DPHVRAGDNV TLACVVTGGN PPPDVSWYLK DRLLSARFQY DLQTQESRNT YSFLAEPEDN
LANYECRASN RKGQAPKTRS IHVKVAYAPQ GVEMTGESNI RQGSVTVVQC RTKENIQEMS
NCRPSNPVSK ISWLVNGHPV PASLQSEHQQ AHGTVSISNL TINTNEVMIG KHRMTVECNA
RNDEGSASKQ HVIKILAPPL PPRISGLEEG VHLEGNVLNV TCEAHGGNPL ADISWYRGYD
KLPGARSSVS GDSAISFLSL TLERTMNGQR LKCEAMNAAL DEPLIDSKQL TVLCEFALTW
YLGGCACIK
//
