ID A0A016VLH1_9BILA Unreviewed; 583 AA.
AC A0A016VLH1;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=KQT-like 1 {ECO:0008006|Google:ProtNLM};
GN Name=Acey_s0007.g3231 {ECO:0000313|EMBL:EYC28454.1};
GN Synonyms=Acey-kqt-3 {ECO:0000313|EMBL:EYC28454.1};
GN ORFNames=Y032_0007g3231 {ECO:0000313|EMBL:EYC28454.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC28454.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC28454.1}.
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DR EMBL; JARK01001343; EYC28454.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VLH1; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
DR GO; GO:0005249; F:voltage-gated potassium channel activity; IEA:InterPro.
DR Gene3D; 1.10.287.70; -; 1.
DR Gene3D; 6.10.140.1910; -; 2.
DR Gene3D; 1.20.120.350; Voltage-gated potassium channels. Chain C; 1.
DR InterPro; IPR005821; Ion_trans_dom.
DR InterPro; IPR003937; K_chnl_volt-dep_KCNQ.
DR InterPro; IPR013821; K_chnl_volt-dep_KCNQ_C.
DR InterPro; IPR027359; Volt_channel_dom_sf.
DR PANTHER; PTHR47735:SF6; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 1; 1.
DR PANTHER; PTHR47735; POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY KQT MEMBER 4; 1.
DR Pfam; PF00520; Ion_trans; 1.
DR Pfam; PF03520; KCNQ_channel; 1.
DR PRINTS; PR00169; KCHANNEL.
DR PRINTS; PR01459; KCNQCHANNEL.
DR SUPFAM; SSF81324; Voltage-gated potassium channels; 1.
PE 4: Predicted;
KW Calmodulin-binding {ECO:0000256|ARBA:ARBA00022860};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..79
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 91..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 134..152
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 198..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 231..251
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 263..289
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 60..294
FT /note="Ion transport"
FT /evidence="ECO:0000259|Pfam:PF00520"
FT DOMAIN 406..544
FT /note="Potassium channel voltage dependent KCNQ C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03520"
FT REGION 366..407
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 552..583
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 386..407
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 583 AA; 66665 MW; AA0B8A7F8528C3C9 CRC64;
MPVEPPAPNK GFQENRISER QAKMFDSRYR TQKERKAAKP TLQSKVYNCL ERPAGWRCFV
YHFSVFVVVL VCLILSVLST VEQHSRFAGE LLFILEIFLV IFFAIEYCVR LWAAGCRSKY
LGFWGRMRFA KKPISFIDLC VVVASITVIL FGNEGQVFAA SAIRGVRFLQ ILRMLHVDRQ
GGTWRLLGSV VFIHRQELIT TLYIGFLGLI FSSYFVYLAE KDHISPDGKQ AFTSYADALW
WGVITMTTIG YGDVVPQTWL GRIVASCFSI FAISFFALPA GILGSGFALK VQQKQRQKHF
NRQIPAAATL IQCLWRCHAA DKDIAATWRV HVDPLAGESN EHHRKQNGSA NDDSISYRRK
LFRKQHSKTS MQLNPKRVRN SAASVDLEMG ERKKEKERNS DVEDDRVFRG ASDSRLDVME
ADEGEDNSLR RISHICELTK QYKDAIRAIR KIKYFVARRR FQQARKPYDV RDVIEQYSQG
HLNMMVRIKE LQRRLDQTLG KPGQDRASRP SVGSSVTIGA RLSRIEMQMM SLERQMNTTL
NLLTTLCRQH SASRRASNVS PSPPFDRPPS ARDSYSPTLS VIQ
//
