ID A0A016VW49_9BILA Unreviewed; 537 AA.
AC A0A016VW49;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Sema domain-containing protein {ECO:0000259|PROSITE:PS51004};
GN Name=Acey_s0003.g1152 {ECO:0000313|EMBL:EYC31620.1};
GN Synonyms=Acey-smp-2 {ECO:0000313|EMBL:EYC31620.1};
GN ORFNames=Y032_0003g1152 {ECO:0000313|EMBL:EYC31620.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC31620.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00352}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC31620.1}.
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DR EMBL; JARK01001339; EYC31620.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VW49; -.
DR STRING; 53326.A0A016VW49; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0030215; F:semaphorin receptor binding; IEA:InterPro.
DR Gene3D; 3.30.1680.10; ligand-binding face of the semaphorins, domain 2; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR002165; Plexin_repeat.
DR InterPro; IPR001627; Semap_dom.
DR InterPro; IPR036352; Semap_dom_sf.
DR InterPro; IPR027231; Semaphorin.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR11036:SF92; SEMA DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11036; SEMAPHORIN; 1.
DR Pfam; PF01437; PSI; 1.
DR Pfam; PF01403; Sema; 2.
DR SMART; SM00630; Sema; 1.
DR SUPFAM; SSF103575; Plexin repeat; 1.
DR SUPFAM; SSF101912; Sema domain; 1.
DR PROSITE; PS51004; SEMA; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..18
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 19..537
FT /note="Sema domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001493982"
FT DOMAIN 9..452
FT /note="Sema"
FT /evidence="ECO:0000259|PROSITE:PS51004"
SQ SEQUENCE 537 AA; 59118 MW; A47FCB5B163A3439 CRC64;
MIAFLVVVIA SLPPPAFAAS AVSVPFFDFT NATSRLRFST DDSLVLLHNY GLHVLLGGRN
AVFNVSVAPL HVEFRYEWAT SNHDRSECTK KTTSLHLCDN YIRTFYLAQR GFVVCGTHGL
NPTCANFLEG ERSPRRIFAG DGLAPHAPDV VAPFLFSGRY LYTANAPDYS STELLLMRKD
PLKVGTSDML RTGRGESQTD GAQFVKLTEN KNEVLAFFSE PPSESEGCGL RRVARIGRVC
RDDTGGTGKH QHEWTSFVKS RLDCAIEGKD QDTLYFNQLA SVTAGAHFLY GAFRSQLAGL
GSSAICAYSR ATVSQTMAGA FRNKKANCPR ANDTYEHTYI RNNPLLPNKL STSPLFVHYG
SDRFAEILTQ ENVVDLAGRH STVFFVATDQ GKVFKIIKNA VEAEARHVSS VKAVEASSPI
VSLTAHVERR PNLQTARKLL ILTPTQLILL PSSMCKQQQT CTDCLSMGDP ECAWVLHGAE
CVAVSENIFR REYLTQELGK CGHQVGEGKT TTEEPPQQRE FTVDWFIRLV SGSPGVA
//
