ID A0A016VW86_9BILA Unreviewed; 518 AA.
AC A0A016VW86;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EYC31670.1};
GN Name=Acey_s0003.g1177 {ECO:0000313|EMBL:EYC31670.1};
GN ORFNames=Y032_0003g1177 {ECO:0000313|EMBL:EYC31670.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC31670.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor
CC beta-D-glucuronoside + H(+) + UDP; Xref=Rhea:RHEA:21032,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:58052, ChEBI:CHEBI:58223,
CC ChEBI:CHEBI:132367, ChEBI:CHEBI:132368; EC=2.4.1.17;
CC Evidence={ECO:0000256|ARBA:ARBA00000301};
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004167}; Single-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004167}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC31670.1}.
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DR EMBL; JARK01001339; EYC31670.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016VW86; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015020; F:glucuronosyltransferase activity; IEA:UniProtKB-EC.
DR CDD; cd03784; GT1_Gtf-like; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR002213; UDP_glucos_trans.
DR PANTHER; PTHR48043; EG:EG0003.4 PROTEIN-RELATED; 1.
DR PANTHER; PTHR48043:SF23; UDP-GLUCURONOSYLTRANSFERASE; 1.
DR Pfam; PF00201; UDPGT; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 4: Predicted;
KW Glycosyltransferase {ECO:0000256|ARBA:ARBA00022676};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 18..518
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5001493988"
FT TRANSMEM 484..507
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 518 AA; 58973 MW; 4DF6E89C42987D0A CRC64;
MLKLQFLLLL HLQLADSYKI LIYSAPLGYS HIKFMGRIAD ILQEAGHDVT VLHQVQDQKY
IPAVSTLTKQ ILHDLPENLQ DKMRPKSFNL WSKESTSLLT HLSLIDTFTQ FHADACDLLL
GDNHTMDTLR NEHFDVGITE TIGACGFGLF ELVGVDHIVC TSAIGVTDSM VSLFDLPNLP
SIVPSIFTPH TDKMNFLERT INFVSTFITT TATTQWMAKY ERVWERHGSS LKARDYYDKV
NYLLSNSDEF LDFARPATPK IVHIGGVTIP EKTELPEELR VLMERKDREG VVYISFGSFV
PTSQMPGYFR DAIFHVAKTF PQITFIWKID ANDTVSTTIP NLHTFTWLPQ LSILDHPNLR
CFVSHGGLNS VLEVTRSGKP SILVPIFGDQ FRNARLVKAK NTTILITKED FNSETFEAAL
RQILSDDSFS VRAKRLASLM VNKPFPLKER LLSTIEFSTR HGKISNLDIN IRELNTLQYY
SIDVVTFLTT LVVLLVASFV QLCRFCFKVL FVRKLKRE
//
