ID   A0A016W4S1_9BILA        Unreviewed;       416 AA.
AC   A0A016W4S1;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=SUEL-type lectin domain-containing protein {ECO:0000259|PROSITE:PS50228};
GN   Name=Acey_s0001.g347 {ECO:0000313|EMBL:EYC34302.1};
GN   Synonyms=Acey-eva-1 {ECO:0000313|EMBL:EYC34302.1};
GN   ORFNames=Y032_0001g347 {ECO:0000313|EMBL:EYC34302.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC34302.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC34302.1}.
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DR   EMBL; JARK01001337; EYC34302.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016W4S1; -.
DR   STRING; 53326.A0A016W4S1; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0030246; F:carbohydrate binding; IEA:InterPro.
DR   CDD; cd22828; Gal_Rha_Lectin_EVA1_EVA1C_rpt1; 1.
DR   CDD; cd22829; Gal_Rha_Lectin_EVA1_EVA1C_rpt2; 1.
DR   Gene3D; 2.60.120.740; -; 2.
DR   InterPro; IPR000922; Lectin_gal-bd_dom.
DR   InterPro; IPR043159; Lectin_gal-bd_sf.
DR   PANTHER; PTHR46780:SF22; MIP32738P1; 1.
DR   PANTHER; PTHR46780; PROTEIN EVA-1; 1.
DR   Pfam; PF02140; Gal_Lectin; 2.
DR   PROSITE; PS50228; SUEL_LECTIN; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        331..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          12..106
FT                   /note="SUEL-type lectin"
FT                   /evidence="ECO:0000259|PROSITE:PS50228"
FT   DOMAIN          115..205
FT                   /note="SUEL-type lectin"
FT                   /evidence="ECO:0000259|PROSITE:PS50228"
SQ   SEQUENCE   416 AA;  46422 MW;  7226132AF739E011 CRC64;
     MDASLRSHRV QACDGEKVTL HCPRNTHIMI ETGFYGRVVP ESQLCPGRIP GRKGYDATCD
     VIQAKSRLSE LCDKKRKCTV YVDTTTFEDD PCPSTSKYLQ MSYKCRPILF DGESFCEGAE
     MQLECREGRR LAMYSATYGR SARGQAAHCT APVHFDRECS RDVLPTLLSK CHAQPGCSLM
     VNSETLGSPC PKDVPSYLSI LFMCVNEEVF SEDAIKGDFE SLQKFIKEME EATSAPVLDD
     GWEKLSEKHI ASEPKVVGPS LSPTNPEPMF SNDAGYVTED RYSLSQGSSK DLDERREELD
     HEQTVEVDAN LVGITHDIMV AVSFVKQNKE KALVCVILSA SLALILLLIA CILQQFCGGR
     RKDKRVPYSI ERSQLIAKSN PILDGPPSLM EMGDFESETF LRYSLSTPPR SSHYDF
//