ID A0A016WPX8_9BILA Unreviewed; 388 AA.
AC A0A016WPX8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=USP domain-containing protein {ECO:0000259|PROSITE:PS50235};
GN Name=Acey_s0573.g165 {ECO:0000313|EMBL:EYC41337.1};
GN ORFNames=Y032_0573g165 {ECO:0000313|EMBL:EYC41337.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC41337.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC41337.1}.
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DR EMBL; JARK01000173; EYC41337.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WPX8; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0004843; F:cysteine-type deubiquitinase activity; IEA:InterPro.
DR Gene3D; 3.90.70.10; Cysteine proteinases; 1.
DR InterPro; IPR038765; Papain-like_cys_pep_sf.
DR InterPro; IPR001394; Peptidase_C19_UCH.
DR InterPro; IPR018200; USP_CS.
DR InterPro; IPR028889; USP_dom.
DR PANTHER; PTHR21646; UBIQUITIN CARBOXYL-TERMINAL HYDROLASE; 1.
DR PANTHER; PTHR21646:SF39; UBIQUITINYL HYDROLASE 1; 1.
DR Pfam; PF00443; UCH; 1.
DR SUPFAM; SSF54001; Cysteine proteinases; 1.
DR PROSITE; PS00972; USP_1; 1.
DR PROSITE; PS50235; USP_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 106..388
FT /note="USP"
FT /evidence="ECO:0000259|PROSITE:PS50235"
FT REGION 74..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 312..341
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 75..93
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 388 AA; 43446 MW; 41CA61A93D9F0A1B CRC64;
MAVCQACNVQ LNPLDDPQDL VKLFSNEYRS FSKTRVEPKV NRKPYEQKSS CNGVIPTQNG
SKVELACVQS SDESVERRTV NDDRPKQVKK ERSSDVMPNN TMIPAKGLAN LGNTCFFNSV
MQCMMHTHHL TYYFHRFGKV SSLNFRQTQT VVVNEEKIEL EPATISVPAD STPLNSVLRG
FIAEFHCGAS PSPGSVFSQI SCKTPRFKGY QQQDAHELLR YLLDGLRSEE LERYKSGIAS
YFGVSPKISK KKVDSETVKL AKGYLQAAGR PLLDMVFGGT LLQTILCSEC GHVSERHEQF
LDLSIPVTLA GSGRSRPGRS VTVNDKRQTQ VKKRGRGKRR VSVQNDNVNE DDIVTPSGPC
IAYEEYEEFT DDEMERLVAG VNRLDFTV
//
