ID A0A016WSQ7_9BILA Unreviewed; 412 AA.
AC A0A016WSQ7;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Fork-head domain-containing protein {ECO:0000259|PROSITE:PS50039};
GN Name=Acey_s0514.g2766 {ECO:0000313|EMBL:EYC42864.1};
GN Synonyms=Acey-fkh-9 {ECO:0000313|EMBL:EYC42864.1};
GN ORFNames=Y032_0514g2766 {ECO:0000313|EMBL:EYC42864.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC42864.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC42864.1}.
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DR EMBL; JARK01000114; EYC42864.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WSQ7; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR CDD; cd00059; FH_FOX; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR001766; Fork_head_dom.
DR InterPro; IPR030456; TF_fork_head_CS_2.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11829; FORKHEAD BOX PROTEIN; 1.
DR PANTHER; PTHR11829:SF399; FORKHEAD TRANSCRIPTION FACTOR FKH-9; 1.
DR Pfam; PF00250; Forkhead; 1.
DR PRINTS; PR00053; FORKHEAD.
DR SMART; SM00339; FH; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00658; FORK_HEAD_2; 1.
DR PROSITE; PS50039; FORK_HEAD_3; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 111..206
FT /note="Fork-head"
FT /evidence="ECO:0000259|PROSITE:PS50039"
FT DNA_BIND 111..206
FT /note="Fork-head"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT REGION 199..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 391..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 412 AA; 46538 MW; 8F83EE64F95E0D0F CRC64;
MSRSAQQHCL PSICECINIY YFVDAPNKVK DVLQKWTLPS LTSFWRAVVP SKVVVLTRRM
VLSRILVGDW FRNGMMDFLN SNPTLQLPQS LSKDEELVTT AEAPRLENIE RPSLSYKDLI
IEAIESSPEK RLKLNEIYQV IRLLHPYYRH RPDQWGWQNS IRHNLSLHDC FVKLPLKQTS
ASGVVGHFWT VVPELSDKQT LRRRNRAPNR GGNRSKPSDP ARETAPVRED PACSGSGETS
PCPSQPSISP PSDLPKPTAS YGGMENILGD SYKAYGQSLL NAYLYQHEDV REYEYKRTKP
CQWSRVIYSF FNLANANYPE SHSSNPGKRC FRPKIRPVSA LSVLFSGLLN SLQQQLVELS
RGNFPSHLLC LNPLLLLSQL KSQVAATSIT NSPPISTSAP TSSIKQETPF LL
//
