ID A0A016WWA2_9BILA Unreviewed; 376 AA.
AC A0A016WWA2;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Serpin domain-containing protein {ECO:0000259|SMART:SM00093};
GN Name=Acey_s0477.g2161 {ECO:0000313|EMBL:EYC43886.1};
GN ORFNames=Y032_0477g2161 {ECO:0000313|EMBL:EYC43886.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC43886.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- SIMILARITY: Belongs to the serpin family.
CC {ECO:0000256|RuleBase:RU000411}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC43886.1}.
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DR EMBL; JARK01000077; EYC43886.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016WWA2; -.
DR MEROPS; I04.081; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR GO; GO:0004867; F:serine-type endopeptidase inhibitor activity; IEA:InterPro.
DR Gene3D; 2.30.39.10; Alpha-1-antitrypsin, domain 1; 1.
DR Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR InterPro; IPR023795; Serpin_CS.
DR InterPro; IPR023796; Serpin_dom.
DR InterPro; IPR000215; Serpin_fam.
DR InterPro; IPR036186; Serpin_sf.
DR InterPro; IPR042178; Serpin_sf_1.
DR InterPro; IPR042185; Serpin_sf_2.
DR PANTHER; PTHR11461:SF211; ACCESSORY GLAND PROTEIN ACP76A-RELATED; 1.
DR PANTHER; PTHR11461; SERINE PROTEASE INHIBITOR, SERPIN; 1.
DR Pfam; PF00079; Serpin; 1.
DR SMART; SM00093; SERPIN; 1.
DR SUPFAM; SSF56574; Serpins; 1.
DR PROSITE; PS00284; SERPIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 23..376
FT /note="Serpin"
FT /evidence="ECO:0000259|SMART:SM00093"
SQ SEQUENCE 376 AA; 42473 MW; EC0E812337169E29 CRC64;
MSNYYYSSSQ SGMFLQAETD FGMKMLRQTS INETCVVSPV SVILALATIH IGAKGQTKSQ
ISRAISTGAT DTEIVKYYSH LSEEIVQHRK GTATTIANGF FMDKKFAVRK SYGSALIKRF
TTKVRSFQFK GNYTLSEKID SYVSRKTYGR IKHIHTPRNL NDALSLLVSA ASFASKWEYS
FVKTLNTRGI FYSRVSSERK VEYMNVVKEN RYYTETENMQ VLSLRYSDTS YALNIFLPRE
KFALETLRAS LTGSVIQTTL SQLKSTYMTI SIPKMRIKTE LKLKTVLRAL GVSELFSDHC
DLSGITKTSA FKISHAAHKA IIEIGEGGTT EKDYGNYYKP VIETEPTYAP TTFIADHPFL
FVLTKDNNPL FIGQYV
//
