ID   A0A016X1B7_9BILA        Unreviewed;       560 AA.
AC   A0A016X1B7;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   RecName: Full=GIY-YIG domain-containing protein {ECO:0000259|PROSITE:PS50164};
GN   Name=Acey_s0421.g1170 {ECO:0000313|EMBL:EYC45631.1};
GN   ORFNames=Y032_0421g1170 {ECO:0000313|EMBL:EYC45631.1};
OS   Ancylostoma ceylanicum.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC   Ancylostomatinae; Ancylostoma.
OX   NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC45631.1, ECO:0000313|Proteomes:UP000024635};
RN   [1] {ECO:0000313|Proteomes:UP000024635}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX   PubMed=25730766; DOI=10.1038/ng.3237;
RA   Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA   Aroian R.V.;
RT   "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT   ceylanicum identify infection-specific gene families.";
RL   Nat. Genet. 47:416-422(2015).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:EYC45631.1}.
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DR   EMBL; JARK01000021; EYC45631.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A016X1B7; -.
DR   STRING; 53326.A0A016X1B7; -.
DR   Proteomes; UP000024635; Unassembled WGS sequence.
DR   Gene3D; 3.30.497.10; Antithrombin, subunit I, domain 2; 1.
DR   Gene3D; 3.40.1440.10; GIY-YIG endonuclease; 1.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR000305; GIY-YIG_endonuc.
DR   InterPro; IPR035901; GIY-YIG_endonuc_sf.
DR   InterPro; IPR023796; Serpin_dom.
DR   InterPro; IPR036186; Serpin_sf.
DR   InterPro; IPR042178; Serpin_sf_1.
DR   PANTHER; PTHR21301; REVERSE TRANSCRIPTASE; 1.
DR   PANTHER; PTHR21301:SF12; REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00079; Serpin; 1.
DR   SUPFAM; SSF82771; GIY-YIG endonuclease; 1.
DR   SUPFAM; SSF56574; Serpins; 1.
DR   PROSITE; PS00018; EF_HAND_1; 1.
DR   PROSITE; PS50164; GIY_YIG; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT   DOMAIN          266..360
FT                   /note="GIY-YIG"
FT                   /evidence="ECO:0000259|PROSITE:PS50164"
SQ   SEQUENCE   560 AA;  63121 MW;  7D5B86ECDCE0DF36 CRC64;
     MCGFAVNDIE ILLEATLACN VFRFNNNFYA QRRGLAMGIR IAPLLAIVYL DHIEKASLTN
     GIILYKRYID DVFAIGSSSS ELAATLANLN AKDENIEFTV EEPDRDGFLP FLNVNVRICD
     DTTEIRWYKK RSSKNIILHS RSAHPAYMKA NVVRNLIGTS ERIAARTSET VDTIKRILFE
     NGYISGNMAT WRPYSAPDGI TLVLPYLNER LAQQVNAIVK RSQLPVRLVF KPPPTLKEIL
     TSSRVYENRC DEEECRYCTD KKICHLRGTV YLIKCNGCGQ RYVGESGRPL RKRLDEHRRA
     FNRPQAYPRN SFSRHRTTVH TRDSPPEFEV TVLHRHLDNP VDRKIMEARE IKRYQPEINN
     LILHNFAVHS LLLLSPHTRM FLAAETDFGL KMLQHAPANE SVVVSPLSVI FAMSMIQAGA
     KGTTKSQIND VISKGASDED TADHYSKLSQ QVLTATDGVQ TRIANAFFLN KGYEVEKDYE
     EAITKKFSAK VESHDFDNAD ETAKQCLCGC VTKGALLGCD WSTPVRVAAA TFTDTSSDGE
     LDRQDFLVRV GQSTIEANKP
//