ID A0A016X1K8_9BILA Unreviewed; 269 AA.
AC A0A016X1K8;
DT 11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT 11-JUN-2014, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Major sperm protein {ECO:0000256|RuleBase:RU003425};
GN Name=Acey_s0416.g1077 {ECO:0000313|EMBL:EYC45795.1};
GN ORFNames=Y032_0416g1077 {ECO:0000313|EMBL:EYC45795.1};
OS Ancylostoma ceylanicum.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Strongyloidea; Ancylostomatidae;
OC Ancylostomatinae; Ancylostoma.
OX NCBI_TaxID=53326 {ECO:0000313|EMBL:EYC45795.1, ECO:0000313|Proteomes:UP000024635};
RN [1] {ECO:0000313|Proteomes:UP000024635}
RP NUCLEOTIDE SEQUENCE.
RC STRAIN=HY135 {ECO:0000313|Proteomes:UP000024635};
RX PubMed=25730766; DOI=10.1038/ng.3237;
RA Schwarz E.M., Hu Y., Antoshechkin I., Miller M.M., Sternberg P.W.,
RA Aroian R.V.;
RT "The genome and transcriptome of the zoonotic hookworm Ancylostoma
RT ceylanicum identify infection-specific gene families.";
RL Nat. Genet. 47:416-422(2015).
CC -!- FUNCTION: Central component in molecular interactions underlying sperm
CC crawling. Forms an extensive filament system that extends from sperm
CC villipoda, along the leading edge of the pseudopod.
CC {ECO:0000256|RuleBase:RU003425}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:EYC45795.1}.
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DR EMBL; JARK01000016; EYC45795.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A016X1K8; -.
DR Proteomes; UP000024635; Unassembled WGS sequence.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR000535; MSP_dom.
DR InterPro; IPR008962; PapD-like_sf.
DR PANTHER; PTHR22947; MAJOR SPERM PROTEIN; 1.
DR PANTHER; PTHR22947:SF12; MAJOR SPERM PROTEIN; 1.
DR Pfam; PF00635; Motile_Sperm; 1.
DR SUPFAM; SSF49354; PapD-like; 1.
DR PROSITE; PS50202; MSP; 1.
PE 4: Predicted;
KW Cytoplasm {ECO:0000256|RuleBase:RU003425};
KW Cytoskeleton {ECO:0000256|RuleBase:RU003425};
KW Reference proteome {ECO:0000313|Proteomes:UP000024635}.
FT DOMAIN 162..269
FT /note="MSP"
FT /evidence="ECO:0000259|PROSITE:PS50202"
FT REGION 62..101
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 269 AA; 28720 MW; 5259735F1FB770D2 CRC64;
MVECFIFACG GYSLCPQGQS LYSDVARRES RLASRSDRAG QAGRSARASH VRVALGAVGA
NEANRGAADP AREEAVEAGG LAKAGEESPS HEARARAGEA AKAQDLVVAN RSPNQGAEGQ
NRVEALGVLA LLLFQVSASS PPNYSGKTRC VRALHQMPKP SELRVEPAEL SYKAIGGLKG
VSVVNDTQER KFFKVKCSDN MLYRVNPVFG AVEPGKSARI DILRQNGGAK IDKIVLVTTK
AQEGEIPCRE VFNQGRSTEM MVLPLLVQE
//
