ID   A0A017H290_9FUSO        Unreviewed;       467 AA.
AC   A0A017H290;
DT   11-JUN-2014, integrated into UniProtKB/TrEMBL.
DT   11-JUN-2014, sequence version 1.
DT   24-JAN-2024, entry version 30.
DE   SubName: Full=Sodium:alanine symporter {ECO:0000313|EMBL:KID48126.1};
GN   ORFNames=C095_12130 {ECO:0000313|EMBL:KID48126.1};
OS   Fusobacterium necrophorum subsp. funduliforme B35.
OC   Bacteria; Fusobacteriota; Fusobacteriia; Fusobacteriales; Fusobacteriaceae;
OC   Fusobacterium.
OX   NCBI_TaxID=1226633 {ECO:0000313|EMBL:KID48126.1, ECO:0000313|Proteomes:UP000031184};
RN   [1] {ECO:0000313|EMBL:KID48126.1, ECO:0000313|Proteomes:UP000031184}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=B35 {ECO:0000313|EMBL:KID48126.1,
RC   ECO:0000313|Proteomes:UP000031184};
RA   Benahmed F.H., Rasmussen M., Harbottle H., Soppet D., Nagaraja T.G.,
RA   Davidson M.;
RT   "An opportunistic ruminal bacterium that causes liver abscesses in
RT   cattle.";
RL   Submitted (AUG-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|RuleBase:RU363064};
CC       Multi-pass membrane protein {ECO:0000256|RuleBase:RU363064}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the alanine or glycine:cation symporter (AGCS)
CC       (TC 2.A.25) family. {ECO:0000256|ARBA:ARBA00009261,
CC       ECO:0000256|RuleBase:RU363064}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:KID48126.1}.
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DR   EMBL; AUZI01000032; KID48126.1; -; Genomic_DNA.
DR   RefSeq; WP_039122682.1; NZ_AOJP01000014.1.
DR   AlphaFoldDB; A0A017H290; -.
DR   PATRIC; fig|1226633.4.peg.2431; -.
DR   OrthoDB; 9804874at2; -.
DR   Proteomes; UP000031184; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005283; F:amino acid:sodium symporter activity; IEA:InterPro.
DR   Gene3D; 1.20.1740.10; Amino acid/polyamine transporter I; 1.
DR   InterPro; IPR001463; Na/Ala_symport.
DR   NCBIfam; TIGR00835; agcS; 1.
DR   PANTHER; PTHR30330; AGSS FAMILY TRANSPORTER, SODIUM-ALANINE; 1.
DR   PANTHER; PTHR30330:SF1; AMINO-ACID CARRIER PROTEIN ALST; 1.
DR   Pfam; PF01235; Na_Ala_symp; 1.
DR   PRINTS; PR00175; NAALASMPORT.
DR   PROSITE; PS00873; NA_ALANINE_SYMP; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475,
KW   ECO:0000256|RuleBase:RU363064};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU363064};
KW   Symport {ECO:0000256|RuleBase:RU363064};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU363064};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU363064}.
FT   TRANSMEM        12..29
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        148..167
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        179..200
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        212..233
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        239..263
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        297..321
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        350..369
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        390..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
FT   TRANSMEM        414..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU363064"
SQ   SEQUENCE   467 AA;  49973 MW;  FB32B245AA1F75E3 CRC64;
     MELVNTINGY LWSYILIGLL LISGIFYTVR TGFAQIFLFG DMVRLVTGKL SALKDGEKRE
     GHQVSAFQAF CISVSSHVGT GNLAGVAIAV VLGGPGALFW MWVTSLIGCA TSLIENTLAQ
     VYKEHDGKGG YRGGPAYYME KALGWKSMAK FFSVIVIITF AFAFNTVQAN TIAQAFEGSF
     GFSPMVVGIV ITILAALVIF GGLQRIANFA GLVVPVMALG YVIVALIVLL MNITHIPALI
     VLIVKSAFGV QAMAGGAMGV AMLQGVKRGL YSNEAGMGSA PNAAATSKVS HPVKQGLLQA
     FGVFIDTIVI CSATGFIVLL LPDYANIGET GIKLTQIALS REVGAWGNPF ITACLFLFAF
     SSVIGNYYYG ETNVEFLSGG NKQVMLVFRL ISVAIIYIGS VAKLSTVWDL ADLSMGIMAI
     MNIVAIAILS PKALHVLQDY RAKRKEGKNP EFHVKDTPEI INTETWE
//